anti-Ubiquitin Protein Ligase E3B (UBE3B) 抗体

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. 再加上,我们可以发UBE3B 蛋白 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
UBE3B 89910 Q7Z3V4
UBE3B 117146 Q9ES34
UBE3B 687633  
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Showing 10 out of 15 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-UBE3B Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  293T cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 IHC, WB Immunohistochemical analysis of UBE3B staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated wi Western blot analysis of UBE3B expression in HEK293T (A), Jurkat (B) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
非结合性 ELISA, WB Western blot analysis of extracts from Jurkat cells, using UBE3B Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
Bat 非结合性 WB 50 μg Log in to see 7至9个工作日
$551.83
详细
非结合性 ELISA, ICC, IF, IHC, WB ABIN6272453 at 1/100 staining Human liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis UBE3B using Jurkat whole cell lysates 100 μL Log in to see 11至12个工作日
$390.77
详细
非结合性 ELISA, IHC, WB   100 μL Log in to see 16 Days
$181.73
详细
非结合性 ELISA, WB 50 μg Log in to see 2至3个工作日
$446.88
详细
非结合性 ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: UBE3B Antibody  - Immunofluorescent staining of human cell line A-431 shows localization to nuclear speckles. 0.1 mL Log in to see 10至13个工作日
$491.63
详细
非结合性 IHC, WB 100 μL Log in to see 11至16个工作日
$312.70
详细
非结合性 WB UBE3B antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 2至3个工作日
$473.93
详细

引用最多的anti-UBE3B 抗体

  1. Cow (Bovine) Polyclonal UBE3B Primary Antibody for WB - ABIN2781245 : Szafranski, Schindler, Taudien, Hiller, Huse, Jahn, Schreiber, Backofen, Platzer: Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns. in Genome biology 2008 (PubMed)

更多抗UBE3B的相互作用对抗体

Human Ubiquitin Protein Ligase E3B (UBE3B) interaction partners

  1. we present four patients with five novel UBE3B mutations and propose the inclusion of clinical features to the characteristics of Kaufman oculocerebrofacial syndrome, including prominence of the cheeks and limb anomalies.

  2. The E3 ligase activity of UBE3B is regulated by its interaction with calmodulin via the N-terminal IQ domain.

  3. Sanger sequencing was negative for the DOORS syndrome gene TBC1D24 (显示 TBC1D24 抗体) but exome sequencing identified a homozygous deletion in UBE3B (NM_183415:c.3139_3141del, p.1047_1047del) located within the terminal portion of the HECT domain

  4. UBE3B encodes a widely expressed protein ubiquitin ligase E3B, which, when mutated in both alleles, causes Kaufman oculocerebrofacial syndrome.

  5. UBE3B mutations cause a clinically recognizable and possibly underdiagnosed syndrome named the Kaufman oculocerebrofacial syndrome

  6. data provide evidence that Kaufman oculocerebrofacial syndrome is caused by UBE3B loss of function, and further demonstrate the impact of misregulation of protein ubiquitination on development and growth.

  7. Our data reveal the pleiotropic effects of UBE3B deficiency and reinforce the physiological importance of ubiquitination in neuronal development and function in mammals.

  8. UBE3B is a novel E3 ligase, with a HECT-domain which constitutes the active site for ubiquitin transfer

Mouse (Murine) Ubiquitin Protein Ligase E3B (UBE3B) interaction partners

  1. Our data reveal the pleiotropic effects of UBE3B deficiency and reinforce the physiological importance of ubiquitination in neuronal development and function in mammals.

UBE3B 抗原简介

蛋白简介

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin-protein ligases. This gene encodes a member of the E3 ubiquitin-conjugating enzyme family which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme and transfers the ubiquitin to the targeted substrates. A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases. Shorter isoforms of this protein which lack the C-terminal HECT domain are therefore unlikely to bind E2 enzymes. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Gene names and symbols associated with UBE3B

  • ubiquitin protein ligase E3B (UBE3B) 抗体
  • ubiquitin protein ligase E3B (ube3b) 抗体
  • ubiquitin-protein ligase E3B (LOC581811) 抗体
  • ubiquitin protein ligase E3B L homeolog (ube3b.L) 抗体
  • ubiquitin protein ligase E3B (Ube3b) 抗体
  • AI449831 抗体
  • AU020130 抗体
  • BPIDS 抗体
  • si:dkey-189p24.3 抗体

Protein level used designations for UBE3B

ubiquitin-protein ligase E3B , ubiquitin protein ligase E3B , ubiquitin-protein ligase E3B-like , ubiquitin protein ligase E3

GENE ID SPECIES
452223 Pan troglodytes
780337 Xenopus (Silurana) tropicalis
581811 Strongylocentrotus purpuratus
100028483 Monodelphis domestica
100338868 Oryctolagus cuniculus
100449551 Pongo abelii
100475409 Ailuropoda melanoleuca
100592402 Nomascus leucogenys
100381000 Xenopus laevis
100394165 Callithrix jacchus
556864 Danio rerio
374194 Gallus gallus
89910 Homo sapiens
486311 Canis lupus familiaris
512750 Bos taurus
117146 Mus musculus
687633 Rattus norvegicus
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