Ubiquitin Associated Protein 1 蛋白 (UBAP1)

UBAP1 is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. 再加上,我们可以发UBAP1 抗体 (63)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
UBAP1 51271 Q9NZ09
UBAP1 67123 Q8BH48
大鼠 UBAP1 UBAP1 362502 Q5XIS7
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Showing 7 out of 9 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
详细
大肠杆菌(E. Coli) His tag   50 μg Log in to see 4 Days
$522.50
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
$414.29
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HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$547.80
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大肠杆菌(E. Coli) 非结合性 SDS-PAGE analysis of Human UBAP1 Protein. 100 μg Log in to see 11至18个工作日
$582.75
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大肠杆菌(E. Coli) 小鼠 非结合性 SDS-PAGE analysis of Mouse UBAP1 Protein. 100 μg Log in to see 11至18个工作日
$611.18
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大肠杆菌(E. Coli) His tag   10 μg Log in to see 15至16个工作日
$300.00
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UBAP1 蛋白 by Origin and Source

Origin 在表达 标记
Human , , ,
, , ,
Mouse (Murine)

更多Ubiquitin Associated Protein 1 (UBAP1)互动伙伴

Human Ubiquitin Associated Protein 1 (UBAP1) interaction partners

  1. Combined targeting of UBAP1 and toll (显示 TLR4 蛋白)-like receptor adaptors TIRAP (显示 TIRAP 蛋白) and MyD88 (显示 MYD88 蛋白) by Pseudomonas aeruginosa PumA (显示 BBC3 蛋白) impedes both cytokine and toll (显示 TLR4 蛋白)-like receptor signalling, highlighting a novel strategy for innate immune evasion.

  2. Results present crystal structures of the coiled-coil domain of the HD-PTP phosphatase and its complex with UBAP1. The coiled-coil domain adopts an unexpected open and rigid conformation. The HD-PTP:UBAP1 structure identifies the molecular determinants of the interaction and provides a molecular basis for the specific functional cooperation between HD-PTP and UBAP1.

  3. The biochemical specificity in ESCRT-I (显示 VPS28 蛋白) assembly is matched by functional specialisation as siRNA-mediated depletion of UBAP1

  4. The upregulation of ubap1 gene expression mainly and the downregulation of p16 gene expression mainly may simultaneously participate in the pathogenesis of acute leukemia.

  5. the identification of differential expression patterns of ubap1 in different tumors.

  6. Decreased expression of UBAP1 protein is a possible point of dysfunction along the pathogenesis pathway for nasopharyngeal carcinoma that may contribute to malignant transformation.

  7. Our data for the first time identifies UBAP1 as a genetic risk factor for FTLD and suggests a mechanistic relationship between this protein and TDP-43 (显示 TARDBP 蛋白).

蛋白简介UBAP1

蛋白简介

This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with UBAP1

  • ubiquitin associated protein 1 (ubap1)
  • ubiquitin associated protein 1 S homeolog (ubap1.S)
  • ubiquitin associated protein 1 (UBAP1)
  • ubiquitin-associated protein 1 (Ubap1)
  • 2700092A01Rik 蛋白
  • MGC89059 蛋白
  • NAG20 蛋白
  • UAP 蛋白
  • Ubap 蛋白
  • UBAP-1 蛋白
  • ubap1b 蛋白
  • zgc:56228 蛋白

Protein level used designations for UBAP1

ubiquitin-associated protein 1 , ubiquitin associated protein 1 , ubiquitin associated protein 1b , ubiquitin-associated protein 1-like , nasopharyngeal carcinoma-associated gene 20 protein , UBAP

GENE ID SPECIES
393183 Danio rerio
447210 Xenopus laevis
448284 Xenopus (Silurana) tropicalis
701140 Macaca mulatta
747117 Pan troglodytes
100053997 Equus caballus
100390559 Callithrix jacchus
100465453 Ailuropoda melanoleuca
100586601 Nomascus leucogenys
51271 Homo sapiens
431652 Gallus gallus
474745 Canis lupus familiaris
100739464 Sus scrofa
517788 Bos taurus
67123 Mus musculus
362502 Rattus norvegicus
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