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The protein encoded by TRIM3 is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. 再加上，我们可以发Tripartite Motif Containing 3 试剂盒 (8) 和 Tripartite Motif Containing 3 蛋白 (6)和数多这个蛋白质的别的产品。
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Human Polyclonal TRIM3 Primary Antibody for ELISA, WB - ABIN250941
El-Husseini, Fretier, Vincent: Cloning and characterization of a gene (RNF22) encoding a novel brain expressed ring finger protein (BERP) that maps to human chromosome 11p15.5. in Genomics 2001
TRIM3 exerted an anti-proliferation role in rheumatoid arthritis fibroblast-like synoviocytes via p38 (显示 CRK 抗体) signaling pathway.
results support a novel role for Brat/TRIM3 in maintaining stem cell equilibrium and suppressing tumor growth by regulating NICD (显示 NOTCH1 抗体) nuclear transport
TRIM3 functions as a tumour suppressor in CRC (显示 CALR 抗体) progression. This tumour-suppressive function is exerted partially through regulation of p53 (显示 TP53 抗体) protein.
Studies indicate most-studied TRIpartite Motif (TRIM (显示 TRAT1 抗体))-NHL (显示 RTEL1 抗体) proteins TRIM2 (显示 TRIM2 抗体), TRIM3, TRIM32 (显示 TRIM32 抗体) and TRIM71 (显示 TRIM71 抗体), and their mutations have been linked to diseases.
TRIM3 may play a significant role in hepatocellular carcinoma progression.TRIM3 is downregulated in hepatocellular carcinoma at both the mRNA and protein levels and that low TRIM3 expression is correlated with an unfavorable prognosis.
TRIM3 acts as a tumor suppressor in GBM by restoring asymmetric cell division.
Data indicate TRIM3 and p21 (显示 CDKN1A 抗体) interact in cells.
TRIM63 (显示 TRIM63 抗体) is a candidate for genes mediating the glucocorticoid-induced promotion of osteoblastic differentiation.
brain-expressed RING finger protein (BERP) is a gene whose expression is up-regulated in a p53 (显示 TP53 抗体)-dependent manner
the endosome-associated protein hrs is a subunit of a protein complex containing actinin-4 (显示 ACTN4 抗体), BERP, and myosin V (显示 MYO5A 抗体) that is necessary for efficient TfR (显示 TFRC 抗体) recycling but not for EGFR (显示 EGFR 抗体) degradation
Temporal control of gamma-actin (显示 ACTG1 抗体) levels by TRIM3 is required to regulate the timing of hippocampal plasticity.
TRIM3, also known as BERP, interacts with KIF21B (显示 KIF21B 抗体) via its RBCC (显示 TRIM17 抗体) domain.
the RING domain is required for TRIM3-induced growth suppression.
Data indicate TRIM3 and p21 (显示 D4S234E 抗体) interact in cells.
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified.
tripartite motif-containing 3
, RING finger protein 97
, brain expressed ring finger
, brain-expressed RING finger protein
, ring finger protein 22
, tripartite motif protein TRIM3
, tripartite motif-containing protein 3
, RING finger protein HAC1
, tripartite motif protein 3