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The protein encoded by TOMM34 is involved in the import of precursor proteins into mitochondria. 再加上，我们可以发Translocase of Outer Mitochondrial Membrane 34 抗体 (74) 和 Translocase of Outer Mitochondrial Membrane 34 蛋白 (8)和数多这个蛋白质的别的产品。
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Data show that Tomm34 extensively interacts with the C-terminal structures of Hsp70 (显示 HSP70 ELISA试剂盒) selectively in its ATP-bound state and that this interaction is strongly entropically driven.
These results suggest that Tomm34 represents a novel scaffolding co-chaperone of Hsp70 (显示 HSP70 ELISA试剂盒) and Hsp90 (显示 HSP90 ELISA试剂盒), which may facilitate Hsp70 (显示 HSP70 ELISA试剂盒)/Hsp90 (显示 HSP90 ELISA试剂盒) cooperation during protein folding
TOMM34 expression in early invasive breast cancer: a biomarker associated with poor outcome.
Results identify Tom34 as a cochaperone of Hsp70/Hsp90 in mitochondrial protein import.
Tom34 unlike Tom20 (显示 TOMM20 ELISA试剂盒) does not interact with the leader sequences of mitochondrial precursor proteins
Yeast two-hybrid screening identifies binding partners of human Tom34 that have ATPase (显示 DNAH8 ELISA试剂盒) activity and form a complex with Tom34 in the cytosol
TOMM34 is involved in the growth of colon cancer cells
Data show that NRF-1 (显示 NFE2L1 ELISA试剂盒) is the main transcription factor regulating the expression of TOMM34, and that Sp1 (显示 PSG1 ELISA试剂盒) interacts with NRF-1 (显示 NFE2L1 ELISA试剂盒) to stimulate the promoter's full activity.
The protein encoded by this gene is involved in the import of precursor proteins into mitochondria. The encoded protein has a chaperone-like activity, binding the mature portion of unfolded proteins and aiding their import into mitochondria. This protein, which is found in the cytoplasm and sometimes associated with the outer mitochondrial membrane, has a weak ATPase activity and contains 6 TPR repeats.
, mitochondrial import receptor subunit TOM34
, outer mitochondrial membrane translocase (34kD)
, translocase of outer membrane 34 kDa subunit
, Tom34a, translocase of outer mitochondrial membrane 34a
, Tom34b, translocase of outer mitochondrial membrane 34b
, translocase of outer mitochondrial membrane 34a
, translocase of outer mitochondrial membrane 34b
, translocase of outer mitochondrial membrane 34