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TPMT 抗体

(Thiopurine S-Methyltransferase (TPMT))
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q. [provided by RefSeq, Jul 2008].
TPMT 抗体  (AA 26-227) TPMT 抗体  (AA 26-227) TPMT 抗体 (AA 26-227) (ABIN7435148)

TPMT 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

TPMT 抗体 TPMT 抗体 TPMT 抗体 (ABIN1501480)

TPMT 适用: 人, 犬 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 4C1 unconjugated

TPMT 抗体  (AA 1-245) TPMT 抗体  (AA 1-245) TPMT 抗体 (AA 1-245) (ABIN563239)

TPMT 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1B5 unconjugated

TPMT 抗体 by 适用

Find TPMT 抗体 for a variety of species such as anti-Human TPMT, anti-Mouse TPMT, anti-Rat TPMT. The species listed below are among those available. Click on a link to go to the corresponding products.

TPMT 抗体 by 应用范围

Find TPMT 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

TPMT 抗体 by 抗体来源

Find TPMT 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

TPMT 抗体 by 抗原表位

Find TPMT 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

TPMT 抗体 by 克隆形成能力

Find available monoclonal or polyclonal TPMT 抗体. Click on a link to go to the corresponding products.

TPMT 抗体 by 克隆

Find TPMT 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

TPMT 抗体 by 标记

Find TPMT 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular TPMT 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7435148
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human
Application WB, IHC, IHC (p), FACS
Validations
  • (6)
Cat. No. ABIN1501480
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (2)
  • (5)
Cat. No. ABIN563239
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IP
Validations
  • (3)
Cat. No. ABIN7171992
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN3021279
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN6265692
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7246526
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7252816
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Pig
Application WB
Validations
  • (1)
Cat. No. ABIN6748459
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IF
Validations
  • (1)
Cat. No. ABIN7257617
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7255179
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7270797
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN1957182
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN1958290
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN1955947
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TPMT 抗体

Hayashi, Naoi, Nakagawa, Nishikawa, Fukuda, Imajoh-Ohmi, Kondo, Kubo, Yabuki, Hattori, Hirouchi, Sugiyama: "Sorting nexin 27 interacts with multidrug resistance-associated protein 4 (MRP4) and mediates internalization of MRP4." in: The Journal of biological chemistry, Vol. 287, Issue 18, pp. 15054-65, (2012) (PubMed).

Milek, Karas Kuzelicki, Smid, Mlinaric-Rascan: "S-adenosylmethionine regulates thiopurine methyltransferase activity and decreases 6-mercaptopurine cytotoxicity in MOLT lymphoblasts." in: Biochemical pharmacology, Vol. 77, Issue 12, pp. 1845-53, (2009) (PubMed).

Egle, Milek, Mlinaric-Rascan, Fahr, Kristl: "A novel gene delivery system for stable transfection of thiopurine-S-methyltransferase gene in versatile cell types." in: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V, Vol. 69, Issue 1, pp. 23-30, (2008) (PubMed).

Wang, Nguyen, McLaughlin, Sikkink, Ramirez-Alvarado, Weinshilboum: "Human thiopurine S-methyltransferase pharmacogenetics: variant allozyme misfolding and aggresome formation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 26, pp. 9394-9, (2005) (PubMed).

Martin, Trouche, Hagemeier, Sørensen, La Thangue, Kouzarides: "Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein." in: Nature, Vol. 375, Issue 6533, pp. 691-4, (1995) (PubMed).

Aliases for TPMT 抗体

thiopurine S-methyltransferase L homeolog (tpmt.L) 抗体
thiopurine S-methyltransferase, tandem duplicate 2 (tpmt.2) 抗体
thiopurine S-methyltransferase TpmT (tpmT) 抗体
thiopurine S-methyltransferase (MCA0794) 抗体
thiopurine S-methyltransferase (Pnap_4948) 抗体
thiopurine S-methyltransferase (Hhal_1383) 抗体
thiopurine S-methyltransferase (TK90_1044) 抗体
thiopurine S-methyltransferase (Slit_1144) 抗体
thiopurine S-methyltransferase (Tint_0842) 抗体
Thiopurine S-methyltransferase (Fbal_3334) 抗体
thiopurine S-methyltransferase (Celly_3188) 抗体
thiopurine S-methyltransferase (Weevi_1737) 抗体
Thiopurine S-methyltransferase (Psefu_2696) 抗体
Thiopurine S-methyltransferase (Metme_3860) 抗体
thiopurine methyltransferase (Tpmt) 抗体
thiopurine S-methyltransferase (TPMT) 抗体
thiopurine S-methyltransferase (Tpmt) 抗体
AW106912 抗体
MGC84277 抗体
NHLRC1 抗体
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