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TRMT1L encodes a protein that has some similarity to N2,N2-dimethylguanosine tRNA methyltransferase from other organisms.
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Includes the identification of the C1orf25 gene.
Functional characterization of the mouse C1orf25 ortholog and comparison to the human protein.
Trm1-like deficient mice are viable and show no anatomical defects; behavioural tests, however, revealed significantly altered motor coordination and aberrant exploratory behaviour thus, Trm1 plays a role in modulating postnatal neuronal functions.
This gene encodes a protein that has some similarity to N2,N2-dimethylguanosine tRNA methyltransferase from other organisms. Studies of the mouse ortholog have shown that this protein plays a role in motor coordination and exploratory behavior, and it may also be involved in modulating postnatal neuronal functions. Alternatively spliced transcripts have been identified for this gene.
chromosome 1 open reading frame 25
, N2,N2-dimethylguanosine tRNA methyltransferase-like
, TRM1-like protein
, TRM1 tRNA methyltransferase 1-like
, TRMT1-like protein