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THO Complex 5 抗体

(THO Complex 5 (THOC5))
Component the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex. Regulates the expression of myeloid transcription factors CEBPA, CEBPB and GAB2 by enhancing the levels of phosphatidylinositol 3,4,5-trisphosphate. May be involved in the differentiation of granulocytes and adipocytes. Essential for hematopoietic primitive cell survival and plays an integral role in monocytic development (By similarity).
THO Complex 5 抗体  (AA 2-53) THO Complex 5 抗体  (AA 2-53) THO Complex 5 抗体 (AA 2-53) (ABIN7172059)

THOC5 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

THO Complex 5 抗体  (Internal Region) THO Complex 5 抗体  (Internal Region) THO Complex 5 抗体 (Internal Region) (ABIN6265558)

THOC5 适用: 人 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

THO Complex 5 抗体  (AA 150-370) THO Complex 5 抗体  (AA 150-370) THO Complex 5 抗体 (AA 150-370) (ABIN6149119)

THOC5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

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Find THO Complex 5 抗体 for a variety of species such as anti-Human THO Complex 5, anti-Mouse THO Complex 5, anti-Rat THO Complex 5. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular THO Complex 5 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7172059
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IF, ICC
Validations
  • (1)
Cat. No. ABIN6265558
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6149119
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC
Validations
Cat. No. ABIN7184908
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB, IHC (p)
Validations
Cat. No. ABIN6286472
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7172062
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7172061
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7172060
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB, IHC, IP, IF
Validations
Cat. No. ABIN7119927
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
Cat. No. ABIN7452096
Quantity 20 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IP, IHC (fp)
Validations
Cat. No. ABIN7453804
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Application IHC
Validations
Cat. No. ABIN7448832
Quantity 25 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
Cat. No. ABIN2878162
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
Cat. No. ABIN7465105
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN7510118
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our THO Complex 5 抗体

Gebhardt, Habjan, Benda, Meiler, Haas, Hein, Mann, Mann, Habermann, Pichlmair: "mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3." in: Nature communications, Vol. 6, pp. 8192, (2015) (PubMed).

Ramachandran, Tran, Klebba-Faerber, Kardinal, Whetton, Tamura: "An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5." in: RNA (New York, N.Y.), Vol. 17, Issue 11, pp. 1957-66, (2011) (PubMed).

Aliases for THO Complex 5 抗体

THO complex 5 (THOC5) 抗体
THO complex 5 (Thoc5) 抗体
THO complex 5 (thoc5) 抗体
THO complex 5 S homeolog (thoc5.S) 抗体
THO complex 5 L homeolog (thoc5.L) 抗体
1700060C24Rik 抗体
A430085L24Rik 抗体
C22orf19 抗体
fc54b09 抗体
Fmip 抗体
fmip 抗体
fSAP79 抗体
PK1.3 抗体
Sgk2 抗体
THOC5 抗体
thoc5 抗体
thoc5-a 抗体
thoc5-b 抗体
wu:fc54b09 抗体
zgc:56190 抗体
zgc:76912 抗体
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