TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1 (TBC1D1) ELISA试剂盒

TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. 再加上,我们可以发TBC1D1 抗体 (58)TBC1D1 蛋白 (5)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
TBC1D1 23216 Q86TI0
大鼠 TBC1D1 TBC1D1 360937  
TBC1D1 57915  
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小鼠 9.37 pg/mL 37.5-2400 pg/mL Typical standard curve 96 Tests Log in to see 15至18个工作日
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适于 TBC1D1 相互作用对的更多 ELISA 试剂盒

Pig (Porcine) TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1 (TBC1D1) interaction partners

  1. the TBC1D1 gene has an effect on meat, carcass and production traits in Italian heavy pigs.

Human TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1 (TBC1D1) interaction partners

  1. TBC1D1-Ser (显示 SIGLEC1 ELISA试剂盒)(231) phosphorylation and/or 14-3-3 (显示 YWHAQ ELISA试剂盒) binding partially mediates AMPK (显示 PRKAA1 ELISA试剂盒)-governed glucose homeostasis and muscle glucose uptake in a context-dependent manner.

  2. data demonstrate heterozygous deactivating TBC1D1 mutations in CAKUT patients with a similar renal and ureteral phenotype, and provide evidence that TBC1D1 mutations may contribute to CAKUT

  3. AS160 and TBC1D1 phosphorylations were evident 30 min after exercise.

  4. Data show that TBC1D1 is expressed and phosphorylated in response to glucose in these cells.

  5. Moderate association of rs9852 indicates an influence of TBC1D1 for antipsychotic-induced weight gain.

  6. R125W mutation occurs in a location of the TBC1D1 PTB (显示 PTBP1 ELISA试剂盒) domain that is predicted to have a function in a putative protein:protein interaction.

  7. Data suggest that insulin (显示 INS ELISA试剂盒) increases phosphorylation of signaling nexus TBC1D1 independent of prior exercise or lipid/Intralipid administration.

  8. TBC1D1 is Ser237 phosphorylated and binding capacity to 14-3-3 protein is increased in skeletal muscle following exercise.

  9. [review] The question of a mechanism for increased phosphorylation of Se (显示 APRT ELISA试剂盒)r237-TBC1D1 after exercise has, so far, not had a straightforward experimental approach for a direct answer in humans undergoing in vivo exercise.

  10. A single bout of exercise regulates TBC1D1 and AS160 phosphorylation on multiple sites in human skeletal muscle.

Mouse (Murine) TBC1 (Tre-2/USP6, BUB2, Cdc16) Domain Family, Member 1 (TBC1D1) interaction partners

  1. in obese leptin (显示 LEP ELISA试剂盒)-deficient mice, lack of TBC1D1 has no impact on feeding behavior or energy intake but results in increased energy expenditure, altered energy substrate preference with increased fatty acid oxidation and suppression of obesity; TBC1D1 may have an evolutionary conserved role in regulating energy homeostasis in vertebrates

  2. These findings demonstrate that the AMPK (显示 PRKAA1 ELISA试剂盒)-TBC1D1 signaling nexus interacts with the PKB (显示 AKT2 ELISA试剂盒)-mTOR (显示 FRAP1 ELISA试剂盒) pathway via IGF1 (显示 IGF1 ELISA试剂盒) secretion, which consequently controls expression of lipogenic genes in the adipose tissue

  3. Rab28 is a substrate for the GAP domains of both TBC1D1 and TBC1D4 in vitro.

  4. Tbc1d1 knockout mice have GLUT4 (显示 SLC2A4 ELISA试剂盒) expression and glucose uptake defects in skeletal muscle and adipose tissue. These defects combine in AS160 KO/Tbc1d1 KO mice, supporting nonredundant functions for AS160 and Tbc1d1.

  5. Data (including data from mice with Tbc1d1 gene deletion) suggest Tbc1d1 controls basal intracellular GLUT4 (显示 SLC2A4 ELISA试剂盒) retention in large skeletal muscles; in small muscles (extensor digitorum longus) Tbc1d1 does not regulate basal GLUT4 (显示 SLC2A4 ELISA试剂盒) cell surface exposure.

  6. Findings indicate that the RabGAP TBC1D1 plays a key role in regulating GLUT4 (显示 SLC2A4 ELISA试剂盒) protein levels and in exercise-mediated glucose uptake in nonoxidative muscle fibers.

  7. TBC1D1-mediated reduction of muscle fatty acid oxidation appears to occur via inhibition of beta-hydroxyaacyl-CoA dehydrogenase activity.

  8. Data from knockout mice suggest that Tbc1d1 is involved in regulation of energy substrate metabolism (glucose vs. lipids) and energy homeostasis; Tbc1d1 plays important role in susceptibility to diabetes type 2, obesity, and hypertriglyceridemia.

  9. Tbc1d1 serves as a key regulator of aminoimidazole carboxamide ribonucleotide-induced GLUT4 (显示 SLC2A4 ELISA试剂盒) liberation

  10. It was shown that TBC1D1 plays a role in regulation of glucose metabolism in skeletal muscle. Moreover, functional TBC1D1 was required for AICA ribonucleotide- or contraction-induced metabolic responses.

TBC1D1 抗原简介

Antigen Summary

TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6\; MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000

Gene names and symbols associated with TBC1D1

  • TBC1 domain family member 1 (TBC1D1) 抗体
  • TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 (tbc1d1) 抗体
  • TBC1 domain family member 1 (LOC100523386) 抗体
  • TBC1 domain family member 1 (tbc1d1) 抗体
  • TBC1 domain family member 1 (Tbc1d1) 抗体
  • TBC1 domain family, member 1 (Tbc1d1) 抗体
  • 1110062G02Rik 抗体
  • AI385682 抗体
  • AW555803 抗体
  • mKIAA1108 抗体
  • TBC 抗体
  • Tbc1 抗体
  • TBC1D1 抗体

Protein level used designations for TBC1D1

TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 , TBC1 domain family member 1-like , TBC1 domain family member 1 , lyncein , TBC1 domain family, member 1 , tre-2/USP6, BUB2, cdc16) domain family, member 1

GENE ID SPECIES
461163 Pan troglodytes
479115 Canis lupus familiaris
561193 Danio rerio
697357 Macaca mulatta
100022584 Monodelphis domestica
100055336 Equus caballus
100082442 Ornithorhynchus anatinus
100352741 Oryctolagus cuniculus
100453546 Pongo abelii
100523386 Sus scrofa
100556335 Anolis carolinensis
100601007 Nomascus leucogenys
23216 Homo sapiens
426162 Gallus gallus
282704 Bos taurus
360937 Rattus norvegicus
57915 Mus musculus
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