TAF4 抗体
(TAF4 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 135kDa (TAF4))
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that has been shown to potentiate transcriptional activation by retinoic acid, thyroid hormone and vitamin D3 receptors. In addition, this subunit interacts with the transcription factor CREB, which has a glutamine-rich activation domain, and binds to other proteins containing glutamine-rich regions. Aberrant binding to this subunit by proteins with expanded polyglutamine regions has been suggested as one of the pathogenetic mechanisms underlying a group of neurodegenerative disorders referred to as polyglutamine diseases. [provided by RefSeq, Jul 2008].
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TAF4 抗体 by 应用范围
Find TAF4 抗体 validated for a specific application such as WB, ELISA, IF, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.
TAF4 抗体 by 抗体来源
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TAF4 抗体 by 抗原表位
Find TAF4 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
TAF4 抗体 by 克隆形成能力
Find available monoclonal or polyclonal TAF4 抗体. Click on a link to go to the corresponding products.
TAF4 抗体 by 克隆
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TAF4 抗体 by 标记
Find TAF4 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
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Latest Publications for our TAF4 抗体
: "Redundant role of tissue-selective TAF(II)105 in B lymphocytes." in: Molecular and cellular biology, Vol. 22, Issue 18, pp. 6564-72, (2002) (PubMed).: "Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription. ..." in: Nature genetics, Vol. 26, Issue 1, pp. 29-36, (2000) (PubMed).
: "Distinct subdomains of human TAFII130 are required for interactions with glutamine-rich transcriptional activators." in: Molecular and cellular biology, Vol. 18, Issue 10, pp. 5734-43, (1998) (PubMed).
: "Human TAF(II)135 potentiates transcriptional activation by the AF-2s of the retinoic acid, vitamin D3, and thyroid hormone receptors in mammalian cells." in: Genes & development, Vol. 11, Issue 11, pp. 1381-95, (1997) (PubMed).
Aliases for TAF4 抗体
TBP-associated factor 4 (Taf4) 抗体Taf4p (TAF4) 抗体
TATA-box binding protein associated factor 4 (TAF4) 抗体
TATA-box binding protein associated factor 4 L homeolog (taf4.L) 抗体
CG5444 抗体
d110 抗体
Dmel\\CG5444 抗体
dmTAF4 抗体
dTAF4 抗体
dTAFII110 抗体
dTAF[[II]]110 抗体
l(3)72Dj 抗体
p110 抗体
SR3-3 抗体
SY3-2 TAF110 抗体
TAF 抗体
TAF2C 抗体
TAF2C1 抗体
TAF4 抗体
TAF4A 抗体
TAF110 抗体
Taf110 抗体
taf110 抗体
TAFII110 抗体
TAFII130 抗体
TAFII135 抗体
TAF[II]110 抗体
TAF[[II]] 抗体
TAF[[II]]110 抗体
Taf[[II]]110 抗体
TFIID 抗体
TFIID 110 抗体
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