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Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. 再加上，我们可以发TAF12 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 20kDa 蛋白 (10) 和 TAF12 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 20kDa 试剂盒 (2)和数多这个蛋白质的别的产品。
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ATF7 (显示 ATF5 抗体) interacts with TAF12 and contributes to the hypersensitivity of OCL (显示 OCLN 抗体) precursors to 1,25-(OH)D in PD.
We show that two genes, TDP1 (显示 TDP1 抗体), a tyrosyl-DNA-phosphdiesterase, and TAF12, an RNA polymerase II TATA-box binding factor, cause CIN (显示 PDXP 抗体) when overexpressed in human cells. Using SDL screens in yeast, we identified a set of genes that when deleted specifically kill cells with high levels of Tdp1 (显示 TDP1 抗体)
TAF12 and NFYC (显示 NFYC 抗体) are transcription factors that regulate the epigenome, whereas RAD54L (显示 ATRX 抗体) plays a central role in DNA repair
ATF7 (显示 AFT7 抗体) interacts with TAF12 and contributes to the hypersensitivity of OCL (显示 OCLN 抗体) precursors to 1,25-(OH)D in PD.
Data present the crystal structure of a complex formed by the interacting domains from two subunits of the general transcription factor TFIID, the human TATA binding protein-associated factors hTAF4 (hTAF(II)135) and hTAF12 (hTAF(II)20).
histone fold domain mediated interaction enhances the DNA binding activity of each of the TAF6 (显示 TAF6 抗体)-TAF9 (显示 TAF9 抗体) and TAF4b-TAF12 pairs and of a histone-like octamer complex composed of the four TAFs
TAF12 hitherto regarded as RNA polymerase II (RNAP II)-specific was found to be also involved in RNAP I transcription.
Findings suggest that DNA binding by TAF4/4b-TAF12 facilitates the association of TFIID with the core promoter of a subset of genes.
Results suggest that RNA polymerase II carboxy-terminal domain phosphorylation is required for efficient pre-mRNA splicing and 3'-end formation in vivo.
Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I. Two transcript variants encoding the same protein have been found for this gene.
, TBP-associated factor
, TBP-associated factor 30kD subunit alpha
, TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20 kDa
, transcription initiation factor TFIID 20 kDa subunits
, transcription initiation factor TFIID subunit 12
, TATA box binding protein (TBP)-associated factor, RNA polymerase II, J, 20kD
, transcription initiation factor TFIID 20/15 kDa subunits
, TFIID subunit p22