anti-Structural Maintenance of Chromosomes 5 (SMC5) 抗体

Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination.

列出全部抗体 基因 基因ID UniProt
 SMC5 SMC5 23137 Q8IY18
小鼠 SMC5 SMC5 226026 Q8CG46
大鼠 SMC5 SMC5 293967  
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antibodies-online.cn销售最多的anti-SMC5 抗体

Showing 10 out of 62 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 IP, WB Detection of human SMC5 in HeLa nuclear extracts using ABIN151916. Immunoprecipitation: SMC5 Antibody [ABIN151916] - 293T whole cell lysate. 100 μL Log in to see 7至9个工作日
$556.31
详细
山羊 非结合性 ELISA, WB   100 μg Log in to see 6至7个工作日
$242.88
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山羊 非结合性 ELISA   0.1 mg Log in to see 2至3个工作日
$446.88
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Cow 山羊 非结合性 ELISA   0.1 mg Log in to see 7至9个工作日
$373.75
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山羊 非结合性 ELISA   100 μg Log in to see 7至9个工作日
$507.83
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非结合性 WB 100 μL Log in to see 16 Days
$476.15
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非结合性 ICC, IF, WB Western Blot: SMC5 Antibody [NBP2-20419] - A: NT2D1. 0.1 mL Log in to see 8至11个工作日
$514.63
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非结合性 ICC, IF, IHC, IHC (p), WB Immunohistochemistry: SMC5 Antibody [NBP2-47271] - Analysis of human prostate shows strong nuclear positivity in glandular cells. Western Blot: SMC5 Antibody [NBP2-47271] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4 0.1 mL Log in to see 10至13个工作日
$491.63
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小鼠 非结合性 ELISA, WB Western Blot detection against Immunogen (38.21 KDa) . 50 μL Log in to see 11至12个工作日
$305.71
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山羊 Alkaline Phosphatase (AP) ELISA   100 μL Log in to see 16 Days
$653.71
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引用最多的anti-SMC5 抗体

  1. Human Polyclonal SMC5 Primary Antibody for IP, WB - ABIN151916 : Draskovic, Arnoult, Steiner, Bacchetti, Lomonte, Londoño-Vallejo: Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination. in Proceedings of the National Academy of Sciences of the United States of America 2009 (PubMed)
    Show all 3 Pubmed References

  2. Cow (Bovine) Polyclonal SMC5 Primary Antibody for ELISA - ABIN4244758 : Pebernard, Perry, Tainer, Boddy: Nse1 RING-like domain supports functions of the Smc5-Smc6 holocomplex in genome stability. in Molecular biology of the cell 2008 (PubMed)

更多抗SMC5的相互作用对抗体

Arabidopsis thaliana Structural Maintenance of Chromosomes 5 (SMC5) interaction partners

  1. The SMC5/6 complex promotes sister chromatid cohesion after DNA breakage and facilitates homologous recombination between sister chromatids.

Human Structural Maintenance of Chromosomes 5 (SMC5) interaction partners

  1. SMC5/6 knockdown rescued HBx-deficient hepatitis b virus replication in human hepatocytes.

  2. High SMC5 protein is associated with hepatitis B.

  3. The SMC5/6 complex physically interacts with the DNA topoisomerase II alpha (TOP2A (显示 TOP2A 抗体)).

  4. results uncover a novel role for the Smc5/6 complex as a restriction factor selectively blocking extrachromosomal DNA transcription; by destroying this complex, HBx relieves the inhibition to allow productive hepatitis B virus gene expression

  5. Structural maintenance of chromosomes (SMC (显示 DYM 抗体)) complexes, which in eukaryotic cells include cohesin, condensin and the Smc5/6 complex, are central regulators of chromosome dynamics

  6. Depletion of Smc5 and Smc6 (显示 SMC6 抗体) resulted in aberrant mitotic chromosome phenotypes that were accompanied by the abnormal distribution of topoisomerase IIalpha (topo IIalpha) and condensins and by chromosome segregation errors

  7. Studies indicate that Nse1 (显示 FAM84A 抗体) may function as a ubiquitin ligase, and is targeted to chromatin through its interaction with the Smc5/6 complex.

  8. the human SMC5/6 complex and the SUMO ligase activity of hMMS21 (显示 NSMCE2 抗体) are required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair in human cells

  9. SMC5/6 complex is recruited to nuclease-induced double-strand breaks (DSBs) and is required for the recruitment of cohesin to DSBs.

  10. SMC5/6 complex facilitates telomere homologous recombination and elongation in alternative lengthening of telomeres cells through SUMOylation of telomere-binding proteins.

Mouse (Murine) Structural Maintenance of Chromosomes 5 (SMC5) interaction partners

  1. age-dependent depletion of the SMC5/6 complex in oocytes could contribute to increased incidence of oocyte aneuploidy and spontaneous abortion in aging females.

Xenopus laevis Structural Maintenance of Chromosomes 5 (SMC5) interaction partners

  1. The Smc5/6 complex is regulated during the cell cycle, presumably in anticipation of DNA damage that may arise during replication.

SMC5 抗原简介

蛋白简介

Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression\; the function seems to be independent of SMC6 (By similarity).

Gene names and symbols associated with SMC5

  • structural maintenance of chromosomes 5 (SMC5) 抗体
  • structural maintenance of chromosomes 5 (smc5) 抗体
  • structural maintenance of chromosomes 5 (Smc5) 抗体
  • structural maintenance of chromosomes 5 S homeolog (smc5.S) 抗体
  • F1N13.60 抗体
  • F1N13_60 抗体
  • mKIAA0594 抗体
  • MLZ-453 抗体
  • mSMC5 抗体
  • SMC-5 抗体
  • Smc5l1 抗体
  • structural maintenance of chromosomes 5 抗体

Protein level used designations for SMC5

SMC protein 5 , structural maintenance of chromosomes protein 5 , SMC-5 , SMC5 structural maintenance of chromosomes 5-like 1 , hSMC5 , protein expressed in male leptotene and zygotene spermatocytes 453

GENE ID SPECIES
831449 Arabidopsis thaliana
445963 Takifugu rubripes
23137 Homo sapiens
476327 Canis lupus familiaris
508938 Bos taurus
226026 Mus musculus
293967 Rattus norvegicus
431608 Gallus gallus
398492 Xenopus laevis
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