anti-Splicing Factor 3b, Subunit 2, 145kDa (SF3B2) 抗体

SF3B2 encodes subunit 2 of the splicing factor 3b protein complex. 再加上,我们可以发Splicing Factor 3b, Subunit 2, 145kDa 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
SF3B2 319322  
SF3B2 10992 Q13435
SF3B2    
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antibodies-online.cn销售最多的anti-Splicing Factor 3b, Subunit 2, 145kDa 抗体

Showing 10 out of 51 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 IF/ICC, IHC, WB Western blot analysis of extracts of various cell lines, using SF3B2 antibody (ABIN5973482) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded rat liver using SF3B2 antibody (ABIN5973482) at dilution of 1/100 (40x lens). 100 μL Log in to see 11至16个工作日
$426.40
详细
非结合性 ICC, IF, IHC (p), IP, IHC, WB Immunohistochemistry-Paraffin: SF3B2 Antibody [ABIN2567197] - Detection of Human SF3b145/SAP145 by Immunohistochemistry. Sample: FFPE section of human stomach carcinoma. Antibody: Affinity purified rabbit anti- SF3b145/SAP145 used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit. 0.1 mL Log in to see 7至9个工作日
$556.31
详细
小鼠 非结合性 ELISA, IF, IHC, IHC (p), WB 100 μg Log in to see 7至9个工作日
$537.17
详细
非结合性 EIA, WB Western blot analysis using SF3B2 Antibody (Center) Cat.-No AP53869PU-N in A549 cell line lysates (35ug/lane). This demonstrates the SF3B2 antibody detected the SF3B2 protein (arrow). 0.4 mL Log in to see 6至8个工作日
$390.50
详细
小鼠 非结合性 IF, IHC, WB Immunofluorescence of monoclonal antibody to SF3B2 on HeLa cell (antibody concentration 60 µg/mL). SF3B2 monoclonal antibody (M01), clone 5D2 Western Blot analysis of SF3B2 expression in Hela NE. 100 μg Log in to see 8至11个工作日
$461.00
详细
非结合性 ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: SF3B2 Antibody [NBP1-92380] - Staining of human colon shows strong nuclear positivity in glandular cells. Immunocytochemistry/Immunofluorescence: SF3B2 Antibody [NBP1-92380] - Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli. 0.1 mL Log in to see 10至13个工作日
$491.63
详细
非结合性 ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: SF3B2 Antibody [ABIN2567208] - Section of human linitis plastica stomach cancer. 0.1 mL Log in to see 7至9个工作日
$556.31
详细
非结合性 IF, IHC, WB 100 μL Log in to see 16 Days
$334.77
详细
非结合性 IF, IHC, WB Western blot analysis of extracts of various cell lines, using SF3B2 antibody. Immunohistochemistry of paraffin-embedded human lung cancer using SF3B2 antibody. 120 μL Log in to see 12至14个工作日
$251.90
详细
非结合性 WB SF3B2 Antibody (Center)  western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SF3B2 antibody detected the SF3B2 protein (arrow). All lanes : Anti-SF3B2 Antibody (Center) at 1:2000 dilution Lane 1: 293 whole cell lysate Lane 2: A431 whole cell lysate Lane 3: A549 whole cell lysate Lane 4: Hela whole cell lysate Lane 5: mouse spleen lysate Lane 6: mouse testis lysate Lane 7: rat lung lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 100 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:2000 400 μL Log in to see 10至11个工作日
$335.50
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引用最多的anti-Splicing Factor 3b, Subunit 2, 145kDa 抗体

  1. Human Polyclonal SF3B2 Primary Antibody for ICC, IF - ABIN256720 : Yang, Hadjikyriacou, Xia, Gayatri, Kim, Zurita-Lopez, Kelly, Guo, Li, Clarke, Bedford: PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145. in Nature communications 2015 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal SF3B2 Primary Antibody for ICC, IF - ABIN256719 : Tresini, Warmerdam, Kolovos, Snijder, Vrouwe, Demmers, van IJcken, Grosveld, Medema, Hoeijmakers, Mullenders, Vermeulen, Marteijn: The core spliceosome as target and effector of non-canonical ATM signalling. in Nature 2015 (PubMed)

更多抗Splicing Factor 3b, Subunit 2, 145kDa的相互作用对抗体

Human Splicing Factor 3b, Subunit 2, 145kDa (SF3B2) interaction partners

  1. Splicing complex SF3B depletion impairs DNA end resection and hampers homologous recombination repair. SF3B controls CtIP (显示 RBBP8 抗体) function at, as least, two levels: by affecting CtIP (显示 RBBP8 抗体) mRNA levels and controlling CtIP (显示 RBBP8 抗体) recruitment to DNA breaks, in a way that requires ATM (显示 ATM 抗体)-mediated phosphorylation of SF3B2 at serine 289.

  2. a docking model based on NOESY measurements suggests that residues 607-616 of the SF3b145 fragment adopt a helical structure that binds to RRM1 (显示 RRM1 抗体) predominantly via alpha1, consequently exhibiting a helix-helix interaction in almost antiparallel.

  3. High SF3B2 expression is associated with hepatocellular carcinoma.

  4. Although amino acid substitutions of residues surrounding Arg-508 had no great effect on PRMT9 (显示 FBXO11 抗体) recognition of SF3B2, moving the arginine residue within this sequence abolished methylation.

  5. Inhibiting the induction of two proteins involved in two of the most significantly upregulated cellular processes, ribosome biogenesis (eIF6 (显示 EIF6 抗体)) and hnRNA splicing (SF3B2/SF3B4 (显示 SF3B4 抗体)), showed that human T cells can enter the cell cycle without growing in size.

  6. Data show that Vpr induces checkpoint activation and G(2) arrest by binding to the CUS1 domain of SAP145 and interfering with the functions of the SAP145 and SAP49 (显示 SF3B4 抗体) proteins, two subunits of the multimeric splicing factor 3b (显示 SF3B14 抗体) (SF3b).

Splicing Factor 3b, Subunit 2, 145kDa (SF3B2) 抗原简介

蛋白简介

This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.

Gene names and symbols associated with SF3B2

  • splicing factor 3b, subunit 2 (Sf3b2) 抗体
  • splicing factor 3b subunit 2 (SF3B2) 抗体
  • splicing factor 3B subunit 2 (LOC714747) 抗体
  • splicing factor 3b subunit 2 L homeolog (sf3b2.L) 抗体
  • splicing factor 3b subunit 2 (sf3b2) 抗体
  • 145kDa 抗体
  • 2610311M13Rik 抗体
  • 2810441F20Rik 抗体
  • B230398H18Rik 抗体
  • Cus1 抗体
  • sap145 抗体
  • SF3b1 抗体
  • SF3B2 抗体
  • SF3B145 抗体
  • sf3b150 抗体

Protein level used designations for SF3B2

splicing factor 3B subunit 2 , splicing factor 3b, subunit 2, 145kDa , splicing factor 3B subunit 2-like , SAP 145 , pre-mRNA splicing factor SF3b 145 kDa subunit , pre-mRNA-splicing factor SF3b 145 kDa subunit , spliceosome associated protein 145 , spliceosome-associated protein 145

GENE ID SPECIES
319322 Mus musculus
451343 Pan troglodytes
476015 Canis lupus familiaris
531931 Bos taurus
714747 Macaca mulatta
734465 Xenopus laevis
100052173 Equus caballus
100170589 Xenopus (Silurana) tropicalis
100445486 Pongo abelii
100483831 Ailuropoda melanoleuca
100522004 Sus scrofa
10992 Homo sapiens
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