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SPAM1 抗体

(Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) (SPAM1))
Hyaluronidase degrades hyaluronic acid, a major structural proteoglycan found in extracellular matrices and basement membranes. Six members of the hyaluronidase family are clustered into two tightly linked groups on chromosome 3p21.3 and 7q31.3. This gene was previously referred to as HYAL1 and HYA1 and has since been assigned the official symbol SPAM1\; another family member on chromosome 3p21.3 has been assigned HYAL1. This gene encodes a GPI-anchored enzyme located on the human sperm surface and inner acrosomal membrane. This multifunctional protein is a hyaluronidase that enables sperm to penetrate through the hyaluronic acid-rich cumulus cell layer surrounding the oocyte, a receptor that plays a role in hyaluronic acid induced cell signaling, and a receptor that is involved in sperm-zona pellucida adhesion. Abnormal expression of this gene in tumors has implicated this protein in degradation of basement membranes leading to tumor invasion and metastasis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
SPAM1 抗体  (AA 100-300) SPAM1 抗体  (AA 100-300) SPAM1 抗体 (AA 100-300) (ABIN1513554)

SPAM1 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated

SPAM1 抗体  (Internal Region) SPAM1 抗体  (Internal Region) SPAM1 抗体 (Internal Region) (ABIN6265252)

SPAM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

SPAM1 抗体  (AA 346-445) SPAM1 抗体  (AA 346-445) SPAM1 抗体 (AA 346-445) (ABIN562973)

SPAM1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

SPAM1 抗体 by 适用

Find SPAM1 抗体 for a variety of species such as anti-Human SPAM1, anti-Mouse SPAM1, anti-Rat SPAM1. The species listed below are among those available. Click on a link to go to the corresponding products.

SPAM1 抗体 by 应用范围

Find SPAM1 抗体 validated for a specific application such as ELISA, WB, IF, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

SPAM1 抗体 by 抗体来源

Find SPAM1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

SPAM1 抗体 by 抗原表位

Find SPAM1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SPAM1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal SPAM1 抗体. Click on a link to go to the corresponding products.

SPAM1 抗体 by 克隆

Find SPAM1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

SPAM1 抗体 by 标记

Find SPAM1 抗体 with a specific conjugate such as FITC, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SPAM1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC
Validations
  • (6)
Cat. No. ABIN1513554
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN6265252
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (6)
  • (1)
Cat. No. ABIN562973
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF
Validations
  • (1)
Cat. No. ABIN7260191
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IC
Validations
  • (2)
Cat. No. ABIN7306106
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7155968
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7155966
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7155965
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7155967
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
Cat. No. ABIN7119388
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
Cat. No. ABIN7136913
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN6749150
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN1537320
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN6865733
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN6849670
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our SPAM1 抗体

Panogeorgou, Tserbini, Filou, Vynios, Naxakis, Papadas, Goumas, Mastronikolis: "Hyaluronan synthases and hyaluronidases in nasal polyps." in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, Vol. 273, Issue 7, pp. 1801-8, (2016) (PubMed).

Li, Yang, Chen, Guan, Du, Guo, Wang, Wang, Li, Jiang, Li: "Expression of a functional recombinant oleosin-human hyaluronidase hPH-20 fusion in Arabidopsis thaliana." in: Protein expression and purification, Vol. 103, pp. 23-7, (2014) (PubMed).

Redgrove, Anderson, McLaughlin, OBryan, Aitken, Nixon: "Investigation of the mechanisms by which the molecular chaperone HSPA2 regulates the expression of sperm surface receptors involved in human sperm-oocyte recognition." in: Molecular human reproduction, Vol. 19, Issue 3, pp. 120-35, (2013) (PubMed).

Kaessler, Olgen, Jose: "Autodisplay of catalytically active human hyaluronidase hPH-20 and testing of enzyme inhibitors." in: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Vol. 42, Issue 1-2, pp. 138-47, (2010) (PubMed).

Monzón, Manzanares, Schmid, Casalino-Matsuda, Forteza: "Hyaluronidase expression and activity is regulated by pro-inflammatory cytokines in human airway epithelial cells." in: American journal of respiratory cell and molecular biology, Vol. 39, Issue 3, pp. 289-95, (2008) (PubMed).

in: (PubMed).

Aliases for SPAM1 抗体

sperm adhesion molecule 1 (Spam1) 抗体
sperm adhesion molecule 1 (SPAM1) 抗体
sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) L homeolog (spam1.L) 抗体
sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) (SPAM1) 抗体
sperm adhesion molecule 1 (spam1) 抗体
AV039194 抗体
HYA1 抗体
HYAL1 抗体
HYAL3 抗体
HYAL5 抗体
im:6902904 抗体
Ph-20 抗体
PH-20 抗体
PH20 抗体
SPAG15 抗体
Spam 抗体
spam1 抗体
XEH1 抗体
zgc:158668 抗体
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