Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1) ELISA试剂盒

SPOCK1 encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. 再加上,我们可以发SPOCK1 抗体 (30)SPOCK1 蛋白 (7)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
SPOCK1 6695 Q08629
大鼠 SPOCK1 SPOCK1 306759  
小鼠 SPOCK1 SPOCK1 20745  
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产品编号 适用 灵敏度 范围 图像 规格 交付 价格 详细
0.061 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13至16个工作日
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Human Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1) interaction partners

  1. The elevated SPOCK1 expression is closely correlated with cancer metastasis and patient survival, and SPOCK1 promotes the invasion and metastasis of gastric cancer through Slug-mediated epithelial-mesenchymal transition.

  2. Testican-1 blood level is related to the severity of sepsis and Testican-1 could be used as a biomarker to determine the severity of sepsis.

  3. Overexpression of SPOCK1was confirmed in head and neck squamous cell carcinoma clinical specimens. Overexpression of SPOCK1 contributes to the aggressive nature of HNSCC.

  4. High SPOCK1 expression is associated with castration-resistant prostate cancer.

  5. downregulation of both strands of pre-miR-150 and overexpression of SPOCK1 are involved in esophageal squamous cell carcinoma (ESCC). pathogenesis. The involvement of passenger strand miRNAs in the regulation of cancer cell aggressiveness is a novel concept in RNA research

  6. is significantly upregulated in osteosarcoma tissue.

  7. Functional assessment in cocultures demonstrated that SPOCK1 strongly affects the composition of the extracellular collagen matrix and by doing so, enables invasive tumor cell growth in Pancreatic ductal adenocarcinoma.

  8. Transcriptomic analysis of EPCR-silenced tumors unveiled an effect mediated by matricellular SPOCK1/testican 1. SPOCK1 silencing suppressed in vitro 3D growth. SPOCK1 ablation decreased orthotopic tumor growth and reduced metastatic osteolytic tumors. High SPOCK1 levels were also associated with poor clinical outcome in a subset of breast cancer patients.

  9. a novel TGF-beta-induced myoepithelial marker and enhanced invasion in breast cancer cells and correlated with poor prognosis

  10. Our results suggested that microRNA-129-5p could directly specifically suppress SPOCK1, which might be one of the potential mechanisms in inhibiting cell processes including viability, proliferation, cell mitosis, migration, and invasiveness of gastric cancer cells.

  11. SPOCK1 expression is significantly up-regulated in colorectal cancer tissues and associated with tumor size and stage. SPOCK1 stimulates the PI3K/AKT signaling pathway to inhibit cell apoptosis and promote tumor growth.

  12. findings suggest that SPOCK1 is a critical mediator of tumor growth and metastasis in prostate cancer

  13. Knockdown of SPOCK1 inhibits the proliferation.

  14. This study suggests that SPOCK1 promotes proliferation, migration and invasion in glioma cells by activating PI3K/AKT and Wnt/beta-catenin pathways, which provides a potential theoretical basis for clinical treatment of glioma.

  15. SPOCK1 is highly expressed in ovarian cancer.SPOCK1 contributes to ovarian cancer development and metastasis.

  16. These results suggest that up-regulation of SPOCK1 in ESCC induces EMT, thus promotes migration and invasion in ESCC cells.

  17. Collectively, altered expression of PKP1 and SPOCK1 appears to be a frequent and critical event in prostate cancer

  18. SPOCK1 activates PI3K/Akt signaling.

  19. Testican-1-induced EMT signaling.

  20. this study showed that SPOCK1 is a novel metastasis related biomarker in lung cancer and may be new diagnostic and therapeutic target for lung cancer.

Mouse (Murine) Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1) interaction partners

  1. Testican-1 blood level is related to the severity of sepsis and Testican-1 could be used as a biomarker to determine the severity of sepsis.

  2. results suggest a possibility that testican-1 plays a permissive role for regenerating axons in reactive astrocytes after injury

  3. limits the accumulation of adipose tissue in mice in part through its demonstrated effects on the regulation of cell shape and production of extracellular matrix

  4. SPARC is counter-adhesive for murine lens epithelial cells. We also identify SPARC as a modulator of LN-1 secretion and deposition, an activity important in epithelial cell-ECM interactions in the ocular lens.

  5. Testican-1 is not critical for mouse development [review]

SPOCK1 抗原简介

Antigen Summary

This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition.

Gene names and symbols associated with SPOCK1

  • SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1 (SPOCK1) 抗体
  • sparc/osteonectin, cwcv and kazal like domains proteoglycan 1 (Spock1) 抗体
  • sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 (Spock1) 抗体
  • Spock 抗体
  • testican 抗体
  • TIC1 抗体
  • Ticn1 抗体

Protein level used designations for SPOCK1

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 , sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 , testican-1 , testican-1-like , testican 1

GENE ID SPECIES
416304 Gallus gallus
462085 Pan troglodytes
511211 Bos taurus
715989 Macaca mulatta
100223935 Taeniopygia guttata
100398533 Callithrix jacchus
100443494 Pongo abelii
100478104 Ailuropoda melanoleuca
100542336 Meleagris gallopavo
100583164 Nomascus leucogenys
6695 Homo sapiens
474688 Canis lupus familiaris
100620623 Sus scrofa
306759 Rattus norvegicus
20745 Mus musculus
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