Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 蛋白 (SLC8A3)

SLC8A3 encodes a member of the sodium/calcium exchanger integral membrane protein family. 再加上,我们可以发Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 抗体 (56)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
SLC8A3 6547 P57103
大鼠 SLC8A3 SLC8A3 140448 P70549
SLC8A3 110893  
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
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Insect Cells 小鼠 rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 60至65个工作日
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
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SLC8A3 蛋白 by Origin and Source

Origin 在表达 标记
Human ,
, ,
Mouse (Murine)
,

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Human Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 (SLC8A3) interaction partners

  1. These results...suggest that cells can use a dynamic Ca(2+) signaling toolkit in which the NCX3 sub-cellular localization changes in synchrony with the cell cycle

  2. Structure-Dynamic Coupling Through Ca(2+)-Binding Regulatory Domains of Mammalian NCX Isoform/Splice Variants

  3. stimulation of NCX3 by PKA occurred through residue S524. This effect may well participate in the fight-or-flight response in skeletal muscle and the long-term potentiation in hippocampus.

  4. In the discovery phase, 60 loci not previously associated with rheumatoid arthritis risk showed evidence for association and were tested for replication in the validation cohort. A total of 12 loci were replicated at the nominal level. When combining the discovery and validation cohorts, an intronic SNP in SLC8A3 was found to be associated with ACPA-positive rheumatoid arthritis at a genome-wide level of significance.

  5. Ayloid beta mediates calpain cleavage of NCX3 in Alzheimer's disease brain.

  6. NCX1 and NCX3 -represent two promising druggable targets for setting on new strategies in stroke therapy.

  7. NCX isoforms (NCX2, NCX3) contribute to mitochondrial Na(+)/Ca(2+) exchange in human DAergic neurons and may act downstream of PINK1 in the prevention of neurodegeneration by m[Ca(2+)] accumulation.

  8. the large cytosolic loop of NCX1, NCX2, and NCX3 is involved in acquisition of immunosuppressive drug specificity

  9. Functional studies, as well as mRNA and protein expression analyses, revealed that NCX1 and NCX3, but not NCX2, were divergently modulated during OPC differentiation into oligodendrocyte.

  10. human macrophages and monocytes express NCX1 and NCX3 that operate in a bidirectional manner to restore [Ca(2+)](i) to generate Ca(2+) signals and to induce TNF-alpha production.

  11. calcium signaling mediated by NCX3 has a crucial role in oligodendrocyte maturation and myelin formation.

  12. Human platelets express K(+) -independent Na(+) /Ca(2+) exchangers NCX1.3, NCX3.2 and NCX3.4.

  13. Data suggest that NCX-mediated Ca(2+) fluxes normally exist in human ASM (potentially contributing to rapid Ca(2+) fluxes), and contribute to enhanced [Ca(2+)](i) regulation in airway inflammation.

  14. Results demonstrate a selective regulation of NCX1, NCX2 and NCX3 isoforms in Alzheimer's disease cortex, specifically in terminals containing amyloid-beta.

  15. The gene promoter of the human isoform of this protein is controlled by cAMP and calcium.

  16. This review examines the regulatory features and expression pattern of the SLC8A3 gene which suggest that NCX3 activity could be crucial in neuronal functions such as memory formation and sensory processing.

  17. Studies show that both alternatively spliced variants can be translated into protein.

  18. The downregulation of the regulator of Ca2+ homeostasis NCX3 by Ca2+-regulated DREAM is a striking example of the autoregulatory property of the Ca2+ signal in neurons.

  19. plasma membrane Na+/Ca2+ exchangers have inhibitory interactions with the 14-3-3 proteins

蛋白简介Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 (SLC8A3)

蛋白简介

This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described.

Gene names and symbols associated with SLC8A3

  • solute carrier family 8 member A3 (SLC8A3)
  • solute carrier family 8 (sodium/calcium exchanger), member 3 (SLC8A3)
  • solute carrier family 8 (sodium/calcium exchanger), member 3 (slc8a3)
  • solute carrier family 8 member A3 (Slc8a3)
  • solute carrier family 8 (sodium/calcium exchanger), member 3 (Slc8a3)
  • AW742262 蛋白
  • Ncx3 蛋白
  • SLC8A3 蛋白

Protein level used designations for SLC8A3

solute carrier family 8 (sodium-calcium exchanger), member 3 , solute carrier family 8 member 3 , solute carrier family 8 (sodium/calcium exchanger), member 3 , sodium/calcium exchanger 3-like , Na(+)/Ca(2+)-exchange protein 3 , Na+/Ca2+ exchanger 3 , sodium/calcium exchanger 3 , sodium/calcium exchanger SLC8A3 , sodium-calcium exchanger

GENE ID SPECIES
467491 Pan troglodytes
490755 Canis lupus familiaris
100034161 Equus caballus
100152101 Sus scrofa
100339605 Oryctolagus cuniculus
100412630 Callithrix jacchus
100471755 Ailuropoda melanoleuca
100487508 Xenopus (Silurana) tropicalis
100541915 Meleagris gallopavo
100603298 Nomascus leucogenys
6547 Homo sapiens
140448 Rattus norvegicus
540307 Bos taurus
110893 Mus musculus
395759 Gallus gallus
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