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The protein encoded by SLC22A7 is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. 再加上，我们可以发Solute Carrier Family 22 (Organic Cation Transporter), Member 7 抗体 (32) 和 Solute Carrier Family 22 (Organic Cation Transporter), Member 7 蛋白 (3)和数多这个蛋白质的别的产品。
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SLC22A7 variants were not significantly associated with hyperuricemia and gout in a New Zealand Maori and Pacific cohort.
Two novel variants in SLC22A17 and SLC22A7 were significantly associated with anthracycline-induced cardiotoxicity.
suggest that OAT2-mediated cGMP uptake does not occur via exchange with monocarboxylates, dicarboxylates, and hydroxyl ions
the findings revealed the important role of OAT2 in renal secretion and possible reabsorption of creatinine and suggested a molecular basis for potential species difference in the transporter handling of creatinine
At physiologic creatinine concentrations, specific activity of OAT2 transport was over twofold higher than OCT2 or OCT3 (显示 POU5F1 ELISA试剂盒), establishing OAT2 as a likely creatinine transporter, challenging the view that creatinine is solely transported by a cationic pathway
mitochondrial pathways may affect SLC (显示 CCL21 ELISA试剂盒) 22A7 function to promote the occurrence of hepatocellular carcinoma
Benzoic acid and specific 2-oxo acids activate hepatic efflux of glutamate (显示 GRIN1 ELISA试剂盒) at OAT2
Transport of the antivirals into human embryonic kidney cells was stimulated 10- to 20-fold by expression of OAT2.
Expression of rat OAT2 in HEK (显示 EPHA3 ELISA试剂盒) (human embryonic kidney)-293 cells stimulates accumulation of zwitterion trigonelline; subsequently, orotic acid is identified as an excellent and specific substrate of OAT2 from human.
results suggest that genetic polymorphisms may not be a significant contributing factor to variations in the hOAT2 expression or hOAT2 transport activity
there exists a sex- and species-related differential gene expression of the OAT2 isoform.
Results indicate that mOAT2 plays a role for the transport of bumetanide on the luminal membranes of kidney proximal tubules.
OAT2 in mouse kidney exhibiting gender differences (F > M) that appear in puberty and are caused by strong androgen inhibition and weak estrogen and progesterone stimulation
propionate (3-carbon SCFA) was transported by mOat2 in a time-dependent manner.
The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described.
, liver-specific transporter
, novel liver transporter
, organic anion transporter 2
, solute carrier family 22 member 7
, renal organic anion transporter 2