电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

SCN1A 抗体

(Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))
The vertebrate sodium channel is a voltage-gated ion channel essential for the generation and propagation of action potentials, mainly in nerve and muscle. Voltage-sensitive sodium channels are heteromeric complexes consisting of a large central pore-forming glycosylated alpha subunit, and two smaller auxiliary beta subunits. This gene encodes the large alpha subunit, and mutations in this gene have been associated with several epilepsy, convulsion and migraine disorders. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, the exact combination of which have not been experimentally confirmed for the full-length transcript.[provided by RefSeq, Jan 2011].
SCN1A 抗体  (AA 992-1099) SCN1A 抗体  (AA 992-1099) SCN1A 抗体 (AA 992-1099) (ABIN7169916)

SCN1A 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated

SCN1A 抗体  (AA 481-515) SCN1A 抗体  (AA 481-515) SCN1A 抗体 (AA 481-515) (ABIN6243309)

SCN1A 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB57630 unconjugated

SCN1A 抗体 SCN1A 抗体 SCN1A 抗体 (ABIN7238339)

SCN1A 适用: 人, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

SCN1A 抗体 by 适用

Find SCN1A 抗体 for a variety of species such as anti-Human SCN1A, anti-Rat SCN1A, anti-Mouse SCN1A. The species listed below are among those available. Click on a link to go to the corresponding products.

SCN1A 抗体 by 应用范围

Find SCN1A 抗体 validated for a specific application such as WB, ELISA, IHC, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

SCN1A 抗体 by 抗体来源

Find SCN1A 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

SCN1A 抗体 by 抗原表位

Find SCN1A 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SCN1A 抗体 by 克隆形成能力

Find available monoclonal or polyclonal SCN1A 抗体. Click on a link to go to the corresponding products.

SCN1A 抗体 by 克隆

Find SCN1A 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

SCN1A 抗体 by 标记

Find SCN1A 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular SCN1A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IF
Validations
  • (2)
Cat. No. ABIN7169916
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (2)
Cat. No. ABIN6243309
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Rat
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7238339
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, WB, IF, IP, ICC
Validations
  • (3)
Cat. No. ABIN7043638
Quantity 25 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN6263501
Quantity 100 μL
Datasheet Datasheet

Application IHC (p)
Validations
  • (1)
Cat. No. ABIN5587499
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
Cat. No. ABIN735923
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7169918
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7169917
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7169915
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7169919
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Rat
Application ELISA, WB
Validations
Cat. No. ABIN6390400
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
Cat. No. ABIN2884660
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC (p)
Validations
Cat. No. ABIN4901987
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN3044542
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SCN1A 抗体

Wimmer, Harty, Richards, Phillips, Miyazaki, Nukina, Petrou: "Sodium channel β1 subunit localizes to axon initial segments of excitatory and inhibitory neurons and shows regional heterogeneity in mouse brain." in: The Journal of comparative neurology, Vol. 523, Issue 5, pp. 814-30, (2015) (PubMed).

Freeman, Desmazières, Simonnet, Gatta, Pfeiffer, Aigrot, Rappeneau, Guerreiro, Michel, Yanagawa, Barbin, Brophy, Fricker, Lubetzki, Sol-Foulon: "Acceleration of conduction velocity linked to clustering of nodal components precedes myelination." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 3, pp. E321-8, (2015) (PubMed).

Tian, Wang, Ke, Guo, Shu: "Molecular identity of axonal sodium channels in human cortical pyramidal cells." in: Frontiers in cellular neuroscience, Vol. 8, pp. 297, (2014) (PubMed).

Li, Tian, Scalmani, Frassoni, Mantegazza, Wang, Yang, Wu, Shu: "Action potential initiation in neocortical inhibitory interneurons." in: PLoS biology, Vol. 12, Issue 9, pp. e1001944, (2014) (PubMed).

Papale, Makinson, Christopher Ehlen, Tufik, Decker, Paul, Escayg: "Altered sleep regulation in a mouse model of SCN1A-derived genetic epilepsy with febrile seizures plus (GEFS+)." in: Epilepsia, Vol. 54, Issue 4, pp. 625-34, (2013) (PubMed).

Xiao, Bosch, Nerbonne, Ornitz: "FGF14 localization and organization of the axon initial segment." in: Molecular and cellular neurosciences, Vol. 56, pp. 393-403, (2013) (PubMed).

Vega, Avila, Matthews: "Interaction between the transcriptional corepressor Sin3B and voltage-gated sodium channels modulates functional channel expression." in: Scientific reports, Vol. 3, pp. 2809, (2013) (PubMed).

Puthussery, Venkataramani, Gayet-Primo, Smith, Taylor: "NaV1.1 channels in axon initial segments of bipolar cells augment input to magnocellular visual pathways in the primate retina." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 41, pp. 16045-59, (2013) (PubMed).

Wykes, Kalmbach, Eliava, Waters: "Changes in the physiology of CA1 hippocampal pyramidal neurons in preplaque CRND8 mice." in: Neurobiology of aging, Vol. 33, Issue 8, pp. 1609-23, (2012) (PubMed).

Kim, Gersbacher, Inquimbert, Kovacs: "Reduced sodium channel Na(v)1.1 levels in BACE1-null mice." in: The Journal of biological chemistry, Vol. 286, Issue 10, pp. 8106-16, (2011) (PubMed).

Aliases for SCN1A 抗体

sodium voltage-gated channel alpha subunit 1 (SCN1A) 抗体
sodium voltage-gated channel alpha subunit 9 (SCN9A) 抗体
sodium channel, voltage-gated, type I, alpha (Scn1a) 抗体
sodium voltage-gated channel alpha subunit 1 (Scn1a) 抗体
B230332M13 抗体
EIEE6 抗体
FEB3 抗体
FEB3A 抗体
FHM3 抗体
GEFSP2 抗体
HBSCI 抗体
NAC1 抗体
Nav1.1 抗体
SCN1 抗体
SCN1A 抗体
SCN9A 抗体
SMEI 抗体
You are here:
客服