Small Proline Rich Protein 2A (SPRR2A) ELISA试剂盒

Cross-linked envelope protein of keratinocytes. 再加上,我们可以发SPRR2A 抗体 (26)SPRR2A 蛋白 (3)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
 SPRR2A SPRR2A 6700 P35326
SPRR2A 20755 Q9CQK8
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小鼠 5.86 pg/mL n/a Typical standard curve 96 Tests 15至18个工作日
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Human Small Proline Rich Protein 2A (SPRR2A) interaction partners

  1. Assessment of SPRR2A protein expression in a clinical cohort of patients with head and neck squamous cell carcinoma (HNSCC) confirmed common SPRR2A downregulation in primary tumors and lymph node metastases, but not in normal tissue. High expression of SPRR2A in lymph node metastases was, along with nonoropharyngeal location of the primary tumor, an independent prognostic factor for regional disease recurrence.

  2. Expression of SPRR1 and of SPRR2A is increased in mucosal samples from patients with chronic rhinosinusitis and appeared as a downstream result of TNF alpha modulation, which possibly resulted in epithelial barrier dysfunction.

  3. SPRR2a modulates ZEB-1 signaling by way of miR-200c/141-associated epithelial mesenchyme transition through SH3-domain networks and contributes to benign and malignant wound-healing responses.

  4. SPRR2A-associated tumor behavior was mimicked by MUC1 shRNA, which induced EMT and, like SPRR2A+ cells, showed reduced metastatic capabilities

  5. SPRR2A functions as a suppressor of p53-dependent transcriptional activity, which otherwise might impede cellular processes needed for epithelial wound repair responses.

  6. Association of psoriasis to PGLYRP and SPRR genes at PSORS4 locus on 1q shows heterogeneity between Finnish, Swedish and Irish families.

  7. Small proline-rich proteins (SPRR2A) function as SH3 domain ligands, increase resistance to injury and are associated with epithelial-mesenchymal transition (EMT) in cholangiocytes.

Mouse (Murine) Small Proline Rich Protein 2A (SPRR2A) interaction partners

  1. Sprr2a is selectively expressed in the upper layer of the epithelium surrounding taste buds in the circumvallate papilla

  2. Immunohistochemical staining revealed that Sprr2a protein is detected only in the adult uterus, and not in the ovary, oviduct or testis.

  3. In non-lesional HPV8-CER transgenic skin StefinA and Sprr2 are indirect/direct transcriptional targets of HPV8

  4. Data show that SPRR2a and b are allergen- and IL-13-induced in experimental allergic responses that may be involved in disease pathophysiology.

  5. Small proline-rich proteins (SPRR2A) function as SH3 domain ligands, increase resistance to injury and are associated with epithelial-mesenchymal transition (EMT) in cholangiocytes.

SPRR2A 抗原简介

Antigen Summary

Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.

Gene names and symbols associated with SPRR2A

  • small proline-rich protein 2A (SPRR2A) 抗体
  • small proline rich protein 2A (SPRR2A) 抗体
  • small proline-rich protein 2A1 (Sprr2a1) 抗体
  • Sprr2a 抗体

Protein level used designations for SPRR2A

small proline-rich protein 2A , type II small proline-rich protein , 2-1 , SPR-2A

GENE ID SPECIES
780523 Ovis aries
6700 Homo sapiens
20755 Mus musculus
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