RNF20 抗体
(Ring Finger Protein 20 (RNF20))
The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012].
recommended
recommended
RNF20 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
recommended
RNF20 抗体 by 适用
Find RNF20 抗体 for a variety of species such as anti-Human RNF20, anti-Mouse RNF20, anti-Rat RNF20. The species listed below are among those available. Click on a link to go to the corresponding products.
RNF20 抗体 by 应用范围
Find RNF20 抗体 validated for a specific application such as WB, ELISA, IF (p), IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.
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RNF20 抗体 by 克隆形成能力
Find available monoclonal or polyclonal RNF20 抗体. Click on a link to go to the corresponding products.
RNF20 抗体 by 克隆
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Reactivity
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Validations
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Cat. No.
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Cat. No.
ABIN527904
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Hamster, Human, Monkey, Mouse, Pig
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Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
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WB, IF (p), IHC (p)
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Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Validations
Cat. No.
ABIN1401679
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p)
Validations
Cat. No.
ABIN1401675
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p)
Validations
Cat. No.
ABIN1401676
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p)
Validations
Cat. No.
ABIN1401677
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF (p)
Validations
Cat. No.
ABIN1401678
Quantity
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Datasheet
Datasheet
Latest Publications for our RNF20 抗体
: "Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy." in: Nucleic acids research, Vol. 45, Issue 3, pp. 1144-1158, (2017) (PubMed).: "Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy." in: Nucleic acids research, (2016) (PubMed).
: "Microarray Analysis Reveals Potential Biological Functions of Histone H2B Monoubiquitination." in: PLoS ONE, Vol. 10, Issue 7, pp. e0133444, (2015) (PubMed).
: "Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 10, pp. 3901-6, (2013) (PubMed).
: "The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2)." in: The Journal of biological chemistry, Vol. 288, Issue 33, pp. 24234-46, (2013) (PubMed).
: "The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination." in: Human molecular genetics, Vol. 21, Issue 3, pp. 559-68, (2012) (PubMed).
: "Histone H2B ubiquitin ligases RNF20 and RNF40 in androgen signaling and prostate cancer cell growth." in: Molecular and cellular endocrinology, Vol. 350, Issue 1, pp. 87-98, (2012) (PubMed).
: "Promoters active in interphase are bookmarked during mitosis by ubiquitination." in: Nucleic acids research, Vol. 40, Issue 20, pp. 10187-202, (2012) (PubMed).
: "Nucleosomal H2B ubiquitylation with purified factors." in: Methods (San Diego, Calif.), Vol. 54, Issue 3, pp. 331-8, (2011) (PubMed).
: "A member of the ETS family, EHF, and the ATPase RUVBL1 inhibit p53-mediated apoptosis." in: EMBO reports, Vol. 12, Issue 7, pp. 682-9, (2011) (PubMed).
Aliases for RNF20 抗体
ring finger protein 20 (RNF20) 抗体ring finger protein 20 (Rnf20) 抗体
4833430L21Rik 抗体
AW540162 抗体
BRE1 抗体
BRE1A 抗体
C79397 抗体
hBRE1 抗体
mKIAA4116 抗体
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