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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit.
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Data indicate that beta hairpin structure present in ribosomal protein S5 (RPS5) is important for IRES-RPS5 interaction.
Mutual effect of human ribosomal proteins S5 and S16 (显示 RPS16 蛋白) on their binding with 18S rRNA fragment 1203-1236/1521-1698
Rps5 has a novel function in osteoclastogenesis and postmenopausal osteoporosis, and is a target for the bone density conservation therapy.
Findings support the concept that genetic manipulation of RPS5 gene expression level (up- and/or downregulation) critically affects the potential of murine erythroleukemia cells to fully complete their erythroid maturation program in vitro.
deregulation of RPS5 gene expression (constitutive expression) affects RPS5 protein level and delays both the onset of initiation of erythroid maturation and entrance in cell cycle arrest in inducer-treated MEL (显示 RAB8A 蛋白) cells.
The results indicate that rpS5 protein enters the nucleus via the region 38-50 aa that forms a random coil as revealed by molecular dynamic simulation.
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
40S ribosomal protein S5
, S5 ribosomal protein
, ribosomal protein S5
, CG8922 gene product from transcript CG8922-RA
, minute 1(o)
, ribosomal protein S5 gene
, ribosomal protein S5a
, transcript e
, ribosomal protein S5 S homeolog