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PTPN13 抗体

(Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Oct 2008].
PTPN13 抗体 PTPN13 抗体 PTPN13 抗体 (ABIN537409)

PTPN13 适用: 人 WB, IP, IHC (p), ICC, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated

PTPN13 抗体  (AA 1965-2173) PTPN13 抗体  (AA 1965-2173) PTPN13 抗体 (AA 1965-2173) (ABIN7174093)

PTPN13 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

PTPN13 抗体  (AA 1-161) PTPN13 抗体  (AA 1-161) PTPN13 抗体 (AA 1-161) (ABIN7444964)

PTPN13 适用: 人 ELISA, WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

PTPN13 抗体 by 适用

Find PTPN13 抗体 for a variety of species such as anti-Human PTPN13, anti-Mouse PTPN13, anti-Rat PTPN13. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find PTPN13 抗体 validated for a specific application such as FACS, IF (cc), IF (p), ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find PTPN13 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

PTPN13 抗体 by 抗原表位

Find PTPN13 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PTPN13 抗体 by 克隆形成能力

Find available monoclonal or polyclonal PTPN13 抗体. Click on a link to go to the corresponding products.

PTPN13 抗体 by 标记

Find PTPN13 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PTPN13 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IP, IHC (p), ICC, IF, IHC (fro)
Validations
  • (1)
  • (3)
Cat. No. ABIN537409
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7174093
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC (p), ICC, IHC (fro)
Validations
  • (2)
Cat. No. ABIN7444964
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application IHC, WB, IP, ICC
Validations
  • (2)
Cat. No. ABIN7444967
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7238954
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB, IF
Validations
  • (2)
Cat. No. ABIN6146442
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN714341
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF
Validations
  • (1)
Cat. No. ABIN7256526
Quantity 200 μL
Datasheet Datasheet
Reactivity Rat
Application IHC, WB, ICC
Validations
  • (2)
Cat. No. ABIN5014216
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN265414
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application IHC (p)
Validations
  • (2)
Cat. No. ABIN2852377
Quantity 250 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN714343
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN896764
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN896763
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN896762
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PTPN13 抗体

Sharma, Carmona, Skowronek, Yu, Collins, Naik, Murzeau, Tseng, Erdmann: "Apoptotic signalling targets the post-endocytic sorting machinery of the death receptor Fas/CD95." in: Nature communications, Vol. 10, Issue 1, pp. 3105, (2019) (PubMed).

Lin, Wang, Hsu, Cho, Yang, Chien: "Capsaicin Induces Autophagy and Apoptosis in Human Nasopharyngeal Carcinoma Cells by Downregulating the PI3K/AKT/mTOR Pathway." in: International journal of molecular sciences, Vol. 18, Issue 7, (2017) (PubMed).

Evrard, Lecce, Michelis, Nomura-Kitabayashi, Pandey, Purushothaman, dEscamard, Li, Hadri, Fujitani, Moreno, Benard, Rimmele, Cohain, Mecham, Randolph, Nabel, Hajjar, Fuster, Boehm, Kovacic: "Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability." in: Nature communications, Vol. 7, pp. 11853, (2016) (PubMed).

Banks, Boanca, Lee, Florens, Washburn: "Proteins interacting with cloning scars: a source of false positive protein-protein interactions." in: Scientific reports, Vol. 5, pp. 8530, (2015) (PubMed).

Ivanov, Lopez Bergami, Maulit, Sato, Sassoon, Ronai: "FAP-1 association with Fas (Apo-1) inhibits Fas expression on the cell surface." in: Molecular and cellular biology, Vol. 23, Issue 10, pp. 3623-35, (2003) (PubMed).

Kachel, Erdmann, Kremer, Wolff, Gronwald, Heumann, Kalbitzer: "Structure determination and ligand interactions of the PDZ2b domain of PTP-Bas (hPTP1E): splicing-induced modulation of ligand specificity." in: Journal of molecular biology, Vol. 334, Issue 1, pp. 143-55, (2003) (PubMed).

Bompard, Puech, Prébois, Vignon, Freiss: "Protein-tyrosine phosphatase PTPL1/FAP-1 triggers apoptosis in human breast cancer cells." in: The Journal of biological chemistry, Vol. 277, Issue 49, pp. 47861-9, (2002) (PubMed).

Meinhold-Heerlein, Stenner-Liewen, Liewen, Kitada, Krajewska, Krajewski, Zapata, Monks, Scudiero, Bauknecht, Reed: "Expression and potential role of Fas-associated phosphatase-1 in ovarian cancer." in: The American journal of pathology, Vol. 158, Issue 4, pp. 1335-44, (2001) (PubMed).

Aliases for PTPN13 抗体

protein tyrosine phosphatase, non-receptor type 13 (PTPN13) 抗体
tyrosine-protein phosphatase non-receptor type 13 (LOC100540743) 抗体
protein tyrosine phosphatase, non-receptor type 13 (ptpn13) 抗体
protein tyrosine phosphatase, non-receptor type 13 (Ptpn13) 抗体
AI324989 抗体
FAP-1 抗体
hPTP1E 抗体
PNP1 抗体
ptp 抗体
PTP-BAS 抗体
PTP-BL 抗体
Ptp-bl 抗体
PTP1E 抗体
PTPL1 抗体
PTPLE 抗体
PTPN13 抗体
Ptpri 抗体
RIP 抗体
wu:fb50g04 抗体
zgc:162319 抗体
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