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putative protein tyrosine phosphatase based on sequence information, may be involved in signal transduction and/or protein amino acid dephosphorylation [RGD, Feb 2006].. 再加上，我们可以发 和 和数多这个蛋白质的别的产品。
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Human Polyclonal PTPN23 Primary Antibody for WB - ABIN525501
Kim, Lee, Heynen-Genel, Suyama, Ono, Lee, Ideker, Aza-Blanc, Gleeson: Functional genomic screen for modulators of ciliogenesis and cilium length. in Nature 2010
Mutations in PTPN23 gene is associated with developmental and epileptic encephalopathy.
HD-PTP/PTPN23 as a prominent haploinsufficient tumor suppressor gene preventing tumor progression through control of integrin trafficking.
the underlying mechanism of PTPN23 function in breast tumorigenesis as that of a key phosphatase that normally suppresses the activity of FYN (显示 FYN 抗体)
The role of HD-PTP/PTPN23 in cancer and tumorigenesis is reviewed.
Results present crystal structures of the coiled-coil domain of the HD-PTP phosphatase and its complex with UBAP1 (显示 UBAP1 抗体). The coiled-coil domain adopts an unexpected open and rigid conformation. The HD-PTP:UBAP1 structure identifies the molecular determinants of the interaction and provides a molecular basis for the specific functional cooperation between HD-PTP and UBAP1 (显示 UBAP1 抗体).
HD-PTP acts as an alternative to ESCRT-II (显示 VPS28 抗体) and VPS20/CHMP6 (显示 CHMP6 抗体) as a link between the ESCRT-I (显示 VPS28 抗体) and those ESCRT-III protein(s) necessary for ILV formation.
Data indicate a regulatory function of non-receptor-type tyrosine phosphatase PTPN23 in maintaining a highly phosphorylated state of survival motor neuron complex protein SMN (显示 STMN1 抗体).
PTPN23 is a tumor suppressor and that repression of PTPN23 expression by miR (显示 MLXIP 抗体)-142-3p plays an important role in the pathogenesis of testicular germ cell tumors.
The ESCRT accessory protein HD-PTP/PTPN23 associates with epidermal growth factor receptor (EGFR (显示 EGFR 抗体)) and combines with the deubiquitinating enzyme UBPY/USP8 (显示 USP8 抗体) to transfer EGFR (显示 EGFR 抗体) from ESCRT-0 to ESCRT-III and drive EGFR (显示 EGFR 抗体) sorting to intralumenal vesicles.
our findings suggest an evolutionarily conserved function of HDPTP-Rab4 (显示 RAB4A 抗体) in the regulation of endocytic trafficking, cell adhesion and migration
HD-PTP affects the intracellular sorting of activated PDGFRbeta and the migration, proliferation and tumorigenicity of cells stimulated by PDGF (显示 PDGFA 抗体).
homozygous gene deletion is lethal around embryonic day 9.5, suggesting that Ptpn23 is an essential requirement for early stages of embryonic development
putative protein tyrosine phosphatase based on sequence information, may be involved in signal transduction and/or protein amino acid dephosphorylation
His-domain protein tyrosine phosphatase
, his domain-containing protein tyrosine phosphatase
, protein tyrosine phosphatase TD14
, tyrosine-protein phosphatase non-receptor type 23
, His domain-containing protein tyrosine phosphatase b
, protein tyrosine phosphatase-like