anti-Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23) 抗体

putative protein tyrosine phosphatase based on sequence information, may be involved in signal transduction and/or protein amino acid dephosphorylation [RGD, Feb 2006].. 再加上,我们可以发和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
PTPN23 25930 Q9H3S7
PTPN23 104831 Q6PB44
PTPN23 117552  
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antibodies-online.cn销售最多的anti-Protein Tyrosine Phosphatase, Non Receptor Type 23 抗体

Showing 10 out of 51 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 IHC, WB Western blot analysis of extracts from HepG2, using PTPN23 antibody. Lane 1 was treated with the blocking peptide. ABIN6273013 at 1/100 staining Human spleen tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL Log in to see 11至12个工作日
$390.77
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非结合性 WB PTPN23 Antibody (C-term)  western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the PTPN23 antibody detected the PTPN23 protein (arrow). 400 μL Log in to see 10至11个工作日
$385.00
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非结合性 IF (p), IHC (p), WB Paraformaldehyde-fixed, paraffin embedded rat brain, Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with HDPTP Polyclonal Antibody  at 1:400 overnight at 4°C, followed by a SP kit and DAB staining. Paraformaldehyde-fixed, paraffin embedded human stomach cancer, Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with HDPTP Polyclonal Antibody  at 1:400 overnight at 4°C, followed by a SP kit and DAB staining. 100 μL Log in to see 14至21个工作日
$317.90
详细
非结合性 ICC, IF, IHC, IHC (p) Immunohistochemistry: PTPN23 Antibody [NBP1-84158] - Staining of human appendix shows cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: PTPN23 Antibody [NBP1-84158] - Analysis of human cell line U-251 MG shows positivity in nucleus but excluded from the nucleoli. Antibody staining is shown in green. 0.1 mL Log in to see 10至13个工作日
$494.38
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小鼠 非结合性 WB Western blot analysis of extracts of various cell lines, using PTPN23 antibody (ABIN5972632) at 1/1000 dilution. 100 μL Log in to see 11至16个工作日
$412.19
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小鼠 非结合性 WB Western Blot analysis of PTPN23 expression in transfected 293T cell line by PTPN23 MaxPab polyclonal antibody.Lane 1: PTPN23 transfected lysate(63.47 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 11至12个工作日
$440.00
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Alexa Fluor 647 IF (p)   100 μL Log in to see 14至21个工作日
$416.90
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Alexa Fluor 555 IF (p)   100 μL Log in to see 14至21个工作日
$416.90
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Alexa Fluor 488 IF (p)   100 μL Log in to see 14至21个工作日
$416.90
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Alexa Fluor 350 IF (p)   100 μL Log in to see 14至21个工作日
$416.90
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引用最多的anti-Protein Tyrosine Phosphatase, Non Receptor Type 23 抗体

  1. Human Polyclonal PTPN23 Primary Antibody for WB - ABIN525501 : Kim, Lee, Heynen-Genel, Suyama, Ono, Lee, Ideker, Aza-Blanc, Gleeson: Functional genomic screen for modulators of ciliogenesis and cilium length. in Nature 2010 (PubMed)

更多抗Protein Tyrosine Phosphatase, Non Receptor Type 23的相互作用对抗体

Human Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23) interaction partners

  1. Our report provides the first description of the clinical phenotype of recessive PTPN23 variants with pathogenicity substantiated by a functional study

  2. Mutations in PTPN23 gene is associated with developmental and epileptic encephalopathy.

  3. HD-PTP/PTPN23 as a prominent haploinsufficient tumor suppressor gene preventing tumor progression through control of integrin trafficking.

  4. the underlying mechanism of PTPN23 function in breast tumorigenesis as that of a key phosphatase that normally suppresses the activity of FYN

  5. The role of HD-PTP/PTPN23 in cancer and tumorigenesis is reviewed.

  6. Results present crystal structures of the coiled-coil domain of the HD-PTP phosphatase and its complex with UBAP1. The coiled-coil domain adopts an unexpected open and rigid conformation. The HD-PTP:UBAP1 structure identifies the molecular determinants of the interaction and provides a molecular basis for the specific functional cooperation between HD-PTP and UBAP1.

  7. HD-PTP acts as an alternative to ESCRT-II and VPS20/CHMP6 as a link between the ESCRT-I and those ESCRT-III protein(s) necessary for ILV formation.

  8. Data indicate a regulatory function of non-receptor-type tyrosine phosphatase PTPN23 in maintaining a highly phosphorylated state of survival motor neuron complex protein SMN.

  9. PTPN23 is a tumor suppressor and that repression of PTPN23 expression by miR-142-3p plays an important role in the pathogenesis of testicular germ cell tumors.

  10. The ESCRT accessory protein HD-PTP/PTPN23 associates with epidermal growth factor receptor (EGFR) and combines with the deubiquitinating enzyme UBPY/USP8 to transfer EGFR from ESCRT-0 to ESCRT-III and drive EGFR sorting to intralumenal vesicles.

  11. our findings suggest an evolutionarily conserved function of HDPTP-Rab4 in the regulation of endocytic trafficking, cell adhesion and migration

  12. HD-PTP degradation by calpains might result in the acquisition of a more aggressive phenotype in neoplastic cells.

  13. loss of PTPN23 may increase the activity of SRC and the phosphorylation status of the E-cadherin/beta-catenin signaling complex to promote tumor growth and invasive behavior in breast cancer

  14. Histidine domain-protein tyrosine phosphatase interacts with Grb2 and GrpL

  15. These results suggest that HD-PTP amounts might be regulated both at the transcriptional and post-transcriptional levels.

  16. data suggest that HD-PTP might participate in modulating endothelial response to angiogenic factors and play a role in regulating the complex events leading to the formation of new vessels

  17. We suggest that HD-PTP contributes to the regulation of endothelial motility by modulating the tyrosine phosphorylation of FAK.

  18. contributes to the regulation of endothelial migration; may play a role in angiogenesis

  19. in Epidermal Growth Factor (EGF) stimulated cells, Src binds to and phosphorylates HD-PTP on tyrosine residues

  20. demonstrate that HD-PTP is a catalytically inactive protein tyrosine phosphatase. As such, we identify one residue involved in its inactivation and show that colony growth reduction activity is independent of its PTP activity status in cancer cell lines

Mouse (Murine) Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23) interaction partners

  1. HD-PTP/PTPN23 as a prominent haploinsufficient tumor suppressor gene preventing tumor progression through control of integrin trafficking.

  2. The role of HD-PTP/PTPN23 in cancer and tumorigenesis is reviewed.

  3. HD-PTP affects the intracellular sorting of activated PDGFRbeta and the migration, proliferation and tumorigenicity of cells stimulated by PDGF.

  4. PTPN23 is a tumor suppressor and that repression of PTPN23 expression by miR-142-3p plays an important role in the pathogenesis of testicular germ cell tumors.

  5. homozygous gene deletion is lethal around embryonic day 9.5, suggesting that Ptpn23 is an essential requirement for early stages of embryonic development

Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23) 抗原简介

蛋白简介

putative protein tyrosine phosphatase based on sequence information, may be involved in signal transduction and/or protein amino acid dephosphorylation

Gene names and symbols associated with PTPN23

  • protein tyrosine phosphatase, non-receptor type 23 (PTPN23) 抗体
  • protein tyrosine phosphatase, non-receptor type 23 (Ptpn23) 抗体
  • protein tyrosine phosphatase, non-receptor type 23, b (ptpn23b) 抗体
  • AI462446 抗体
  • HD-PTP 抗体
  • HDPTP 抗体
  • Ptp-Td14 抗体
  • ptp23b 抗体
  • si:dkeyp-114f9.2 抗体

Protein level used designations for PTPN23

His-domain protein tyrosine phosphatase , his domain-containing protein tyrosine phosphatase , protein tyrosine phosphatase TD14 , tyrosine-protein phosphatase non-receptor type 23 , His domain-containing protein tyrosine phosphatase b , protein tyrosine phosphatase-like , ptpn23

GENE ID SPECIES
25930 Homo sapiens
104831 Mus musculus
117552 Rattus norvegicus
560417 Danio rerio
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