anti-Programmed Cell Death 5 (PDCD5) 抗体

PDCD5 encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. 再加上,我们可以发PDCD5 蛋白 (13)PDCD5 试剂盒 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
PDCD5 9141 O14737
PDCD5 56330 P56812
PDCD5 292814  
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Showing 10 out of 78 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB Western blot analysis of PDCD5 Antibody (N-term) (ABIN653585) in mouse testis tissue lysates (35 µg/lane). PDCD5 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10至11个工作日
$324.50
详细
非结合性 EIA, IF, WB   0.1 mg Log in to see 12至15个工作日
$469.32
详细
非结合性 EIA, IF, WB   0.1 mg Log in to see 12至15个工作日
$469.32
详细
非结合性 IHC (p), ELISA, WB Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7至9个工作日
$484.00
详细
非结合性 ELISA, ICC, IF, WB Immunocytochemistry/Immunofluorescence: PDCD5 Antibody [NBP1-76991] - Jurkat cells with PDCD5 antibody at 5 ug/ml. Western Blot: PDCD5 Antibody [NBP1-76991] - Jurkat cell lysate with PDCD5 antibody at 2.5 ug/ml. 0.1 mg Log in to see 8至11个工作日
$485.88
详细
非结合性 ELISA, WB 100 μg Log in to see 7至9个工作日
$551.83
详细
非结合性 ELISA, ICC, IF, WB Immunocytochemistry/Immunofluorescence: PDCD5 Antibody [NBP1-76988] - Immunofluorescence of PDCD5 in Jurkat cells with PDCD5 antibody at 10 ug/mL. Western Blot: PDCD5 Antibody [NBP1-76988] - EL4 cell lysate with PDCD5 antibody at 1ug/ml. 0.1 mg Log in to see 8至11个工作日
$485.88
详细
非结合性 EIA, IHC (p), WB Human Brain, cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6至8个工作日
$368.50
详细
非结合性 IC, IF, WB Immunofluorescent analysis of PDCD5 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody Western blot analysis of PDCD5 expression in A549 (A), MCF7 (B) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
非结合性 ICC, ELISA, WB   100 μg Log in to see 15至19个工作日
$511.06
详细

通过反应活性、应用领域、克隆类型和共轭标记 PDCD5 抗体

特性 应用范围 宿主 克隆类型 标记
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更多抗PDCD5的相互作用对抗体

Human Programmed Cell Death 5 (PDCD5) interaction partners

  1. DKK-1 (显示 DKK1 抗体) and PDCD5 can be independent predictors of overall survival in patients suffering from chondrosarcoma.

  2. Data show that lower serum levels of programmed cell death protein 5 (PDCD5) protein were identified in the gastric cancer patients that with CD133(+) fraction more than 1.6 %.

  3. Endogenous PDCD5 overexpression accelerated multiple myeloma cell apoptosis under dexamethasone treatment.

  4. Studies indicate that programmed cell death 5 (PDCD5) interacts with the tumor protein p53 (p53 (显示 TP53 抗体)) pathway to promote cell apoptosis.

  5. This review describes what is known about PDCD5 and its cellular functions. [review]

  6. The results suggest a role of PDCD5 in the regulation of p53 (显示 TP53 抗体) function but unrelated to cell cycle arrest or apoptosis, at least in the cell types investigated.

  7. PDCD5 selectively mediates HDAC3 (显示 HDAC3 抗体) dissociation from p53 (显示 TP53 抗体), which induces HDAC3 (显示 HDAC3 抗体) cleavage and ubiquitin-dependent proteasomal degradation. This is a a mechanism for p53 (显示 TP53 抗体) activation via PDCD5-dependent HDAC3 (显示 HDAC3 抗体) decay under genotoxic stress conditions.

  8. PDCD5 expression is negatively correlated with disease progression and stage in ovarian cancer.

  9. These findings uncovered an apoptotic signaling cascade linking YAF2 (显示 YAF2 抗体), PDCD5, and TP53 (显示 TP53 抗体) during genotoxic stress responses.

  10. Transgenic mice with systemic overexpression of human PDCD5 were protected from cardiac remodeling.

Mouse (Murine) Programmed Cell Death 5 (PDCD5) interaction partners

  1. These data demonstrate an association between level of PDCD5 and asthma severity and indicate that PDCD5 may play a role in allergic asthma.

  2. PDCD5 gene knockout mice presented obvious improved brain blood flow, improved neurological behavior and decreased cerebral infarction compared with wild type mice. mice lacking PDCD5 had no changes in the expression of VHL (显示 VHL 抗体) and have slighter increases in the expression of HIF-1alpha (显示 HIF1A 抗体) and BNIP3 (显示 BNIP3 抗体), suggesting that PDCD5 may regulate apoptosis and autophagy through VHL (显示 VHL 抗体)-HIF-1alpha (显示 HIF1A 抗体)-BNIP3 (显示 BNIP3 抗体) pathway.

  3. PDCD5 selectively mediates HDAC3 (显示 HDAC3 抗体) dissociation from p53 (显示 TP53 抗体), which induces HDAC3 (显示 HDAC3 抗体) cleavage and ubiquitin-dependent proteasomal degradation. This is a a mechanism for p53 (显示 TP53 抗体) activation via PDCD5-dependent HDAC3 (显示 HDAC3 抗体) decay under genotoxic stress conditions.

  4. These findings uncovered an apoptotic signaling cascade linking YAF2 (显示 YAF2 抗体), PDCD5, and TP53 (显示 TP53 抗体) during genotoxic stress responses.

  5. Transgenic mice with systemic overexpression of human PDCD5 were protected from cardiac remodeling.

  6. It is implied that overexpression of PDCD5 causes the increase in caspase-3 (显示 CASP3 抗体) activity and the subsequent increase of apoptosis in cochlear hair cells and SGNs, and thereby plays a role in the pathogenesis of presbycusis.

  7. PDCD5 activity in T cells suppresses autoimmunity by modulating regulatory T-cells.

  8. The expression levels of PDCD5 and caspase 3 (显示 CASP3 抗体) in the cochlea of C57 mice increase with age.

  9. Suppresses the pathogenicity of transplanted mouse erythroleukemia (MEL (显示 RAB8A 抗体)) cells in mice.

PDCD5 抗原简介

蛋白简介

This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12

Gene names and symbols associated with PDCD5

  • programmed cell death 5 (pdcd5) 抗体
  • programmed cell death 5 (PDCD5) 抗体
  • programmed cell death 5 S homeolog (pdcd5.S) 抗体
  • DNA-binding protein (SSO_RS01750) 抗体
  • programmed cell death 5 (Pdcd5) 抗体
  • 2200003D22Rik 抗体
  • AA408513 抗体
  • DKFZp468P187 抗体
  • Tfar19 抗体
  • zgc:56315 抗体

Protein level used designations for PDCD5

programmed cell death protein 5 , programmed cell death 5 , hypothetical protein , TF-1 cell apoptosis-related protein 19 , TF1 cell apoptosis-related gene 19 , TFAR19 novel apoptosis-related , TF-1 cell apoptosis related gene-19 protein

GENE ID SPECIES
394152 Danio rerio
415765 Gallus gallus
455920 Pan troglodytes
476499 Canis lupus familiaris
495300 Xenopus laevis
549765 Xenopus (Silurana) tropicalis
702277 Macaca mulatta
1455494 Sulfolobus solfataricus P2
100167298 Acyrthosiphon pisum
100172347 Pongo abelii
100196200 Salmo salar
100528677 Ictalurus punctatus
9141 Homo sapiens
56330 Mus musculus
292814 Rattus norvegicus
509123 Bos taurus
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