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Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. 再加上，我们可以发KCNJ15 蛋白 (6) 和 和数多这个蛋白质的别的产品。
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Human Polyclonal KCNJ15 Primary Antibody for IHC, IHC (p) - ABIN4328478
He, Liu, Chew, Baker, Baker, Forte, Zhu: Acid secretion-associated translocation of KCNJ15 in gastric parietal cells. in American journal of physiology. Gastrointestinal and liver physiology 2011
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KCNJ15 couples with polyamines in sensing weak electric fields.
RNA-seq evidence of biallelic expression of KCNJ15 and 10 neighboring genes in at least one primary human tissue tested indicates that the expression of KCNJ15 is uncoupled from the control of the maternally inherited 5mCpG imprints at the WRB (显示 WRB 抗体) differentially methylated region (DMR (显示 WDR20 抗体)) in disomic controls or trisomy (Down syndrome) individuals.
KCNJ15 has a major role in histamine-stimulated gastric acid secretion.
We had performed a replication study using an independent larger Japanese population for the association of rs3746876 within KCNJ15, and observed a significant association of rs3746876 with type 2 diabetes, but this study failed to find original finding.
It was shown that downregulation of Kcnj15 leads to increased insulin (显示 INS 抗体) secretion in vitro and in vivo. The mechanism for regulating insulin (显示 INS 抗体) secretion inolved a calcium-sensiong receptor.
KCNJ15 is a previously unreported susceptibility gene for T2DM among Asians
The potential synergy and consequences of the overexpression of KIR4.2 and KIR3.2 (显示 KCNJ6 抗体) in Down's syndrome brain development are discussed.
Calcium-sensing receptor (显示 CASR 抗体) interacts directly with Kir4.1 (显示 KCNJ10 抗体) and Kir4.2 and can decrease their currents.
MUPP1 (显示 MPDZ 抗体) and Kir4.2 may participate in a protein complex in the nephron that could regulate transport of K(+) as well as other ions.
Data show that KCNJ15 inward rectifier potassium channel and hyperpolarization-activated cyclic nucleotide-gated (HCN) channel currents are changed in Trisomic neuron.
in nonsecreting parietal cells, KCNJ15 is stored in vesicles distinct from the H(+)-K(+)-ATPase (显示 ATP4b 抗体)-enriched tubulovesicles. Furthermore, upon stimulation, KCNJ15 and H(+)-K(+)-ATPase (显示 ATP4b 抗体) both translocate to the apical membrane for active acid secretion.
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Eight transcript variants encoding the same protein have been found for this gene.
ATP-sensitive inward rectifier potassium channel 15
, inward rectifier K(+) channel Kir1.3
, inward rectifier K(+) channel Kir4.2
, inward rectifier K+ channel KIR4.2
, potassium channel, inwardly rectifying subfamily J member 15
, potassium inwardly-rectifying channel, subfamily J, member 15
, potassium inwardly-rectifying channel, subfamily J, member 1
, inward rectifier K+ channel Kir4.2
, potassium inwardly-rectifying channel J15
, Potassium channel, inwardly rectifying subfamily J member 15