anti-Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) 抗体

PHLDA1 encodes an evolutionarily conserved proline-histidine rich nuclear protein. 再加上,我们可以发PHLDA1 蛋白 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
PHLDA1 22822 Q8WV24
PHLDA1 21664 Q62392
PHLDA1 29380  
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antibodies-online.cn销售最多的anti-PHLDA1 抗体

Showing 10 out of 48 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-PHLDA1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Placenta 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB WB Suggested Anti-PHLDA1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human Placenta 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB 50 μg Log in to see 11至14个工作日
$551.83
详细
Cow 非结合性 WB 50 μg Log in to see 11至14个工作日
$551.83
详细
非结合性 ICC, IF, IHC, IHC (p) Western Blot: PHLDA1 Antibody [NBP1-84969] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells) Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells) Dilution: 1:100 - 1:500 Immunocytochemistry/Immunofluorescence: PHLDA1 Antibody [NBP1-84969] - Staining of human cell line U-251MG shows positivity in nucleus but not nucleoli. 0.1 mL Log in to see 10至13个工作日
$494.38
详细
非结合性 ELISA, WB 100 μL Log in to see 16 Days
$181.73
详细
非结合性 ELISA, WB 100 μL Log in to see 11至14个工作日
$493.17
详细
非结合性 WB PHLDA1 Antibody (N-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PHLDA1 antibody detected the PHLDA1 protein (arrow). 400 μL Log in to see 10至11个工作日
$385.00
详细
非结合性 ELISA, ICC, IF, WB Western blot analysis of extracts from rat brain, using PHLDA1 Antibody. Western blot analysis of PHLDA1 expression in HEK293 cells ,The lane on the left is treated with the antigen-specific peptide. 100 μL Log in to see 11至12个工作日
$390.77
详细
非结合性 WB Western Blot: PHLDA1 Antibody [NBP1-53066] - Human Placenta lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 8至11个工作日
$488.73
详细

引用最多的anti-PHLDA1 抗体

  1. Cow (Bovine) Polyclonal PHLDA1 Primary Antibody for WB - ABIN2785898 : Tsuda, Davis, Argani, Shukla, McGill, Nagai, Saito, Laé, Fisher, Ladanyi: TFE3 fusions activate MET signaling by transcriptional up-regulation, defining another class of tumors as candidates for therapeutic MET inhibition. in Cancer research 2007 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal PHLDA1 Primary Antibody for WB - ABIN2785897 : Nagai, Fregnani, Netto, Brentani, Soares: Down-regulation of PHLDA1 gene expression is associated with breast cancer progression. in Breast cancer research and treatment 2007 (PubMed)
    Show all 2 Pubmed References

更多抗PHLDA1的相互作用对抗体

Human Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) interaction partners

  1. suggest a unique regulatory feature of PHLDA1 to inhibit the ErbB receptor oligomerization process and thereby control the activity of receptor signaling network.

  2. Data identified PHLDA1 as a novel p53 target with an ability to repress Akt. PHLDA1 has a so-called split PH domain divided into an N-terminal and a C-terminal portions and seems to be responsible for its localization to the plasma membrane and binding to phosphatidylinositol. In addition, PHLDA1 expression analysis suggests that PHLDA1 has a tumor suppressive function in breast and ovarian cancers.

  3. Our study negatively correlates expression of PHLDA1 and Aurora A in IMR-32 cells and sheds new light on functions of PHLDA1 in the neuroblastoma tumor cells, suggesting its role as a pro-apoptotic protein

  4. Suggest decreased expression of PHLDA1 may play an important role in tumor progression, and may become a new adjunct biomarker in the prognosis in gastric adenocarcinoma.

  5. Data suggest that high PHLDA1 expression is controlled through an ER-NFkappaB-miR-181 regulatory axis and may contribute to a poor clinical outcome in patients with ER+ breast tumors by enhancing stem-like properties in these tumors.

  6. PHLDA1 expression is a useful addition in differentiating trichoblastoma and basal cell carcinoma.

  7. A role for PHLDA1 as an apoptosis suppressor in oral cancer cells.

  8. Data show that downregulation of aurora A kinase by the therapeutic antibody is associated with decreased levels of MYCN protein in cytoplasm, and induced expression of PHLDA1 and P53 proteins.

  9. The follicular stem cell marker PHLDA1 (TDAG51) indicates that most basaloid tumors in nevus sebaceus are basal cell carcinomas and not trichoblastomas.

  10. PHLDA1 differentiates between desmoplastic trichoepithelioma and morpheaform basal cell carcinoma but shows variable staining in microcystic adnexal carcinoma.

  11. the release of Ca(2+) from endoplasmic reticulum stores mediates epithelial-to-mesenchymal transition in human proximal tubular epithelium via the induction of TDAG51

  12. crucial negative regulator and effector of Aurora A kinase in breast cancer

  13. PHLDA1 expression marks the putative epithelial stem cells, downregulates ITGA2 and ITGA6, and contributes to intestinal tumorigenesis

  14. The progressive loss of PHLDA1 expression in melanomas may play a role in deregulated cell growth and apoptosis resistance in these tumors.

  15. expression of TDAG51 in human T-cells does not correlate with activation-induced cell death

  16. TDAG51 plays an important role in the anti-apoptotic effects of IGF-I.

  17. TDAG51 locus shows an operon-like organization of two head-to-head oriented transcripts that are inversely regulated in T lymphocytes by a CpG-rich bidirectional promoter.

  18. Reduced PHLDA1 expression is important in breast cancer progression and could serve as useful prognostic marker of disease outcome.

  19. TDAG51 in patients with intractable epilepsy was significantly higher when compared with levels in the controls.

  20. The anti-estrogen ICI 182,780 (1 microM) inhibited PHLDA1 mRNA expression and completely abolished the effect of 10 nM 17beta-estradiol on PHLDA1 expression (P < 0.05), suggesting that PHLDA1 is regulated by estrogen via ER.

Mouse (Murine) Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) interaction partners

  1. The data presented herein demonstrate TDAG51 expression to be upregulated in damaged skeletal muscle and its absence attenuates the early phases of muscle regeneration.

  2. PHLDA1 plays a critical role in the development of progressive lung contusion and subsequent inflammation.

  3. These findings suggested that TDAG51 up-regulation is a dependent event during LPS-mediated proliferation and cell cycle progression, and which increase our understanding of the interaction mechanism between LPS and macrophages.

  4. The JAK2-ERK1/2-STAT3 pathway is an important signaling pathway for regulation of PHLDA1 expression.

  5. TDAG51 has a protective role in oxidative stress-induced cell death in mouse embryonic fibroblasts.

  6. Our results suggest that the balance between the cell survival and death signals mediated by HSP70 and TDAG51, respectively, may be disturbed by the altered expression of HSF1 during the progression of disease in this amyotropic lateral sclerosis model.

  7. TDAG51 is involved in energy homeostasis at least in part by regulating lipogenesis in liver and white adipose tissue.

  8. PHLDA1 expression marks the putative epithelial stem cells, downregulates ITGA2 and ITGA6, and contributes to intestinal tumorigenesis

  9. TDAG51 is induced by homocysteine, promotes detachment-mediated PCD, and contributes to the development of atherosclerosis observed in hyperhomocysteinemia

PHLDA1 抗原简介

蛋白简介

This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1.

Gene names and symbols associated with PHLDA1

  • pleckstrin homology like domain family A member 1 (PHLDA1) 抗体
  • pleckstrin homology like domain, family A, member 1 (Phlda1) 抗体
  • pleckstrin homology-like domain, family A, member 1 (Phlda1) 抗体
  • pleckstrin homology-like domain, family A, member 1 L homeolog (phlda1.L) 抗体
  • DT1P1B11 抗体
  • PHRIP 抗体
  • Tdag 抗体
  • TDAG51 抗体

Protein level used designations for PHLDA1

PQ-rich protein , PQR protein , T-cell death-associated gene 51 protein , apoptosis-associated nuclear protein , pleckstrin homology-like domain family A member 1 , proline- and glutamine-rich protein , proline- and histidine-rich protein , proline-histidine rich protein , T-cell death associated

GENE ID SPECIES
22822 Homo sapiens
21664 Mus musculus
29380 Rattus norvegicus
540135 Bos taurus
100036927 Xenopus laevis
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