Use your antibodies-online credentials, if available.
PITX3 encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. 再加上，我们可以发Pituitary Homeobox 3 抗体 (42) 和 Pituitary Homeobox 3 蛋白 (6)和数多这个蛋白质的别的产品。
Study showed that PITX3 methylation was significantly methylated in head and neck squamous cell carcinoma (HNSCC) tumor compared to normal adjacent tissue and correlated with lymph node status. These results provide evidence that PITX3 DNA methylation (显示 HELLS ELISA试剂盒) is an independent prognostic biomarker for overall survival in patients with HNSCC and might aid in the process of risk stratification for individualized treatment.
Study showed that PITX3 and PITX2 (显示 PITX2 ELISA试剂盒) were hypermethylated in prostate carcinomas (PCa (显示 FLVCR1 ELISA试剂盒)) and significantly associated with established clinicopathologic parameters characteristic of PCa (显示 FLVCR1 ELISA试剂盒).
These findings suggest that p.A203fs in PITX3 is the cause of cataracts in the recruited family.
PITX3 variants rs3758549 and rs4919621 are not associated with ET in Chinese Han population.
novel PITX3 mutation c.573del, p.(Ser192Alafs*117), was identified in heterozygous state in a Belgo-Romanian family with a similar phenotype
our data demonstrate that key midbrain dopamine regulators (Nurr1 (显示 NR4A2 ELISA试剂盒), Pitx3, and Lmx1a (显示 LMX1A ELISA试剂盒)) play overlapping as well as distinct roles during neurogenesis and neurotransmitter phenotype determination of mDA neurons
Mutations in PITX3 are not a common cause or a risk factor for multisystem atrophy and progressive supranuclear palsy in the Polish population.
Presence of the rs4919621 allele A in PITX3 significantly increases the risk of Parkinson's disease (PD) patients in a Caucasian population, while rs2281983 allele C and rs4919621 allele A were both risk factors in early onset PD.
This study provided that NURR1 (显示 NR4A2 ELISA试剂盒) and PITX3 gene expression is decreased in the peripheral blood lymphocytes of Chinese patients with Parkinson's disease patients.
novel synonymous SNP in PITX3 gene may contribute to PD risk in the Chinese population.
In Xenopus, pitx3 appears to inhibit the rotation of presomitic cell cohorts and to be necessary to the bilaterally symmetric expression of pitx2 (显示 PITX2 ELISA试剂盒) in somites.
Microarray-based identification of Pitx3 targets during Xenopus embryogenesis.
expression of Pitx3 in the presumptive lens ectoderm is critical for retina development
in absence of En1 (显示 EN1 ELISA试剂盒) and Pitx3, only a limited number of Mesodiencephalic dopaminergic neurons are present in mouse embryo.
Pitx3 is specifically required for DA-related function and, if impaired, Pitx3 could contribute during the pathogenesis of Parkinson's disease.
the sonic hedgehog (显示 SHH ELISA试剂盒) signaling pathway is both necessary and sufficient for the induction of ectopic PITX3 expression in chick mesencephalon downstream of WNT9A (显示 WNT9A ELISA试剂盒)-induced LMX1a (显示 LMX1A ELISA试剂盒) transcription.
microphthalmos/aphakia inPITX3 nonsense mutant is caused by the expression of truncated PITX3, resulting in the abnormal expression of downstream targets and lens fiber proteins.
Pitx3 binds to an evolutionary conserved bicoid-binding site on the 5'-upstream region of Foxe3 (显示 FOXE3 ELISA试剂盒). Pitx3 binding to 5'-upstream region of Foxe3 (显示 FOXE3 ELISA试剂盒) increased transcriptional activity significantly in a cell-based reporter assay.
During fetal myogenesis, Pitx2 (显示 PITX2 ELISA试剂盒)/3 control this redox state through the regulation of Nrf1 (显示 NRF1 ELISA试剂盒) and of antioxidant pathways.
Pitx3 overexpressing mouse significantly affects the gene expression of midbrain dopamine neurons. Motor coordination and locomotion activities are significantly affected in mice overexpressing Pitx3 mice.
Primary fetal neurobehavioral deficit of the Pitx3 mutation is akinesia related to nigrostriatal damage.
Two crucial mediators of mesodiencephalic dopaminergic neuronal development, En1 (显示 EN1 ELISA试剂盒) and Pitx3, interact in dopaminergic subset specification.
a novel link between Pitx3 function and the selective pattern of midbrain dopaminergic neurons cell loss observed in Parkinson's disease.
pitx3 expression in the primordia of the pituitary, lens, olfactory mucosa, and cranial ganglia is modulated by hedgehog (显示 SHH ELISA试剂盒) and nodal proteins' signaling.
results demonstrate zebrafish pitx3 represents a true ortholog of the human PITX3 gene and the general function of the Pitx3 protein in lens development is conserved between mammals and the teleost fish
Data demonstrate that Foxe3 (显示 FOXE3 ELISA试剂盒) is necessary for lens development in zebrafish and that foxe3 (显示 FOXE3 ELISA试剂盒) lies genetically downstream of pitx3 in a zebrafish lens development pathway.
while lmx1b (显示 LMX1B ELISA试剂盒) paralogues may contribute to the generation of diencephalic dopaminergic precursors. Conversely, knock-down of pitx3 does not specifically affect any diencephalic dopamine cluster
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. This protein is involved in lens formation during eye development. Mutations of this gene have been associated with anterior segment mesenchymal dysgenesis and congenital cataracts.
pituitary homeobox 3
, homeobox protein PITX3
, paired-like homeodomain transcription factor 3
, homeobox protein PTX3
, homeodomain transcription factor Pitx-3
, Pituitary homeobox 3 (Homeobox protein PITX3)
, bicoid-like homeodomain transcription factor 3
, bicoid-like homeodomain transcription factor Pitx3