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Protease which may deconjugate SUMO from some substrate proteins (By similarity). 再加上，我们可以发PPPDE Peptidase Domain Containing 1 抗体 (30) 和 PPPDE Peptidase Domain Containing 1 蛋白 (5)和数多这个蛋白质的别的产品。
The PPPDE1 could mediate the ubiquitin chain editing of RPS7 (显示 RPS7 ELISA试剂盒), deubiquitinating Lys (显示 LYZ ELISA试剂盒) 48-linked ubiquitination, and finally stabilize RPS7 (显示 RPS7 ELISA试剂盒) proteins.
DESI2 (显示 PPPDE2 ELISA试剂盒) may influence the AKT (显示 AKT1 ELISA试剂盒)/mTOR (显示 FRAP1 ELISA试剂盒) signal in pancreatic cancer.
findings suggest a novel mechanism by which elevated PNAS-4 first causes DNA-dependent protein kinase (显示 CDK7 ELISA试剂盒)-mediated Chk1 (显示 CHEK1 ELISA试剂盒)/2 activation and then results in inhibition of the Cdc25A (显示 CDC25A ELISA试剂盒)-CDK2 (显示 CDK2 ELISA试剂盒)-cyclin E (显示 CCNE1 ELISA试剂盒)/A pathway
hPNAS-4 inhibits proliferation of ovarian cancer cells by inducing S phase arrest and apoptosis via activation of Cdc25A (显示 CDC25A ELISA试剂盒)-Cdk2 (显示 CDK2 ELISA试剂盒)-Cyclin E (显示 CCNE1 ELISA试剂盒)/Cyclin A (显示 CCNA2 ELISA试剂盒) axis and mitochondrial dysfunction-mediated caspase (显示 CASP3 ELISA试剂盒)-dependent and -independent apoptotic pathways.
PNAS-4 is not a p53 (显示 TP53 ELISA试剂盒) target, but overexpression of PNAS-4 is correlated to p53 (显示 TP53 ELISA试剂盒) inactivity in colorectal cancer.
overexpression of human PNAS4 induced apoptosis and arrested cell cycle in S phase in A549 human lung adenocarcinoma cells.
expression regulation and biological functions of PPPDE1 in development and carcinogenesis.
PNAS4 was not involved in mice brain development and apoptosis.
overexpression of mouse PNAS4 significantly suppressed Lewis lung carcinoma growth and prolonged survival time through induction of tumor cell apoptosis
PNAS-4 gene maps to pig chromosome 10, q11-16, and is upregulated after weaning. Homozygous pigs have a higher fat content.
Protease which may deconjugate SUMO from some substrate proteins (By similarity).
PPPDE peptidase domain-containing protein 1
, UPF0326 protein FAM152A
, family with sequence similarity 152, member A
, PPPDE peptidase domain containing 1
, desumoylating isopeptidase 1