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The protein encoded by PGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). 再加上，我们可以发PGD Synthetase 试剂盒 (22) 和 PGD Synthetase 抗体 (13)和数多这个蛋白质的别的产品。
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These observations suggest that tumor cell-derived inflammatory cytokines increase L-PGDS (显示 PTGDS 蛋白) expression and subsequent PGD2 (显示 PTGDS 蛋白) production in the tumor endothelial cells (ECs). This PGD2 (显示 PTGDS 蛋白) acts as a negative regulator of the tumorigenic changes in tumor ECs.
Exposure of macrophages to cyclooxygenase (COX-2) inhibitors RhoA (显示 RHOA 蛋白) and LA-4 cells to antagonists of prostaglandin E2 (PGE2) receptor , PGD2 (显示 PTGDS 蛋白) receptors or the hepatocyte growth factor (HGF (显示 HGF 蛋白)) receptor c-Met (PHA (显示 LBR 蛋白)-665752), reversed EMT (显示 ITK 蛋白) inhibition by the conditioned medium
Ptgds (显示 PTGDS 蛋白) is targeted and repressed by the CUL4B (显示 CUL4B 蛋白)/PRC2 complex.
Thermodynamic and nuclear magnetic resonance analyses demonstrated that L-PGDS binds to nicotinamide coenzymes, including NADPH, NADP(+), and NADH.
Prostaglandin D2 synthase is a novel MR target (显示 PTGDS 蛋白) gene in adipocytes.
When prostaglandin D2 synthase (显示 PTGDS 蛋白) is upregulated it participates in the regulation of peripheral nervous system myelination.
expression of L-PGDS (显示 PTGDS 蛋白) in mouse lungs decreased neutrophilic infiltration, ameliorating lung inflammation in mice.
Silencing of PTGDS (显示 PTGDS 蛋白) also alleviated H-rev107 (显示 HRASLS 蛋白)-mediated suppression of cell migration and invasion
In this report, we show for the first time that alteration of the P (显示 PTGDS 蛋白)TGDS-governed PGD2 pathway disturbs testicular migration in mice.
Data indicate a PLA2G3 (显示 PLA2G3 蛋白)-lipocalin (显示 APOD 蛋白)-type PGD2 synthase (L-PGDS)-PGD2 (显示 PTGDS 蛋白) receptor DP1 (显示 PTGDR 蛋白) loop that drives mast cell maturation.
Serum levels of beta trace protein and beta 2 microglobulin (显示 B2M 蛋白) can be used to predict residual kidney function in hemodialysis patients.
BTP and B2M (显示 B2M 蛋白) levels are less affected than serum by amputation, and should be considered for future study of GFR (显示 RAPGEF5 蛋白) estimation
Hematopoietic prostaglandin D synthase (显示 HPGDS 蛋白) defines a proeosinophilic pathogenic effector human T(H)2 cell subpopulation with enhanced function
levels of L-PGDS (显示 PTGDS 蛋白) in cervicovaginal secretions of pregnant women at different stages of parturition correlate with preterm birth.
PTGDS (显示 PTGDS 蛋白) mRNA expression was down-regulated in rapid-cycling bipolar disorder patients in a euthymic, depressive, and manic/hypomanic state compared with healthy control subjects.
Expression of MR and prostaglandin D2 synthase (显示 PTGDS 蛋白) is strongly correlated in adipose tissues from obese patients.
These data indicate that scalp is spatially programmed via mast cell prostaglandin D-synthase (显示 PTGDS 蛋白) distribution in a manner reminiscent of the pattern seen in androgenetic alopecia.
These results suggest that L-PGDS (显示 PTGDS 蛋白) acted as a scavenger of biliverdin, which is a molecule not found in normal CSF (显示 CSF2 蛋白).
Lipocalin (显示 APOD 蛋白)-type prostaglandin D2 (PGD2) synthase (L-PGDS) interacts intracellularly with the G protein-coupled receptor (显示 ADRA1A 蛋白) DP1 (显示 PTGDR 蛋白) in an agonist-independent manner.
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.
, glutathione-independent PGD synthase
, glutathione-independent PGD synthetase
, lipocalin-type prostaglandin-D synthase
, prostaglandin D2 synthase (21 kDa, brain)
, prostaglandin-D2 synthase
, prostaglandin-H2 D-isomerase
, Prostaglandin D synthase
, beta-trace protein
, lipocalin-type prostaglandin D synthase
, prostaglandin D synthase