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Osteoactivin 抗体

(Osteoactivin (GPNMB))
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Osteoactivin 抗体  (AA 81-180) Osteoactivin 抗体  (AA 81-180) Osteoactivin 抗体 (AA 81-180) (ABIN749093)

GPNMB 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Osteoactivin 抗体  (AA 31-260) Osteoactivin 抗体  (AA 31-260) Osteoactivin 抗体 (AA 31-260) (ABIN1724859)

GPNMB 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 7C10E5 unconjugated

Osteoactivin 抗体  (AA 104-203) Osteoactivin 抗体  (AA 104-203) Osteoactivin 抗体 (AA 104-203) (ABIN523856)

GPNMB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A8 unconjugated

Osteoactivin 抗体 by 适用

Find Osteoactivin 抗体 for a variety of species such as anti-Human Osteoactivin, anti-Mouse Osteoactivin, anti-Rat Osteoactivin. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find Osteoactivin 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find Osteoactivin 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

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Find Osteoactivin 抗体 with a specific conjugate such as Biotin, FITC, PE. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Osteoactivin 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (6)
  • (2)
  • (1)
Cat. No. ABIN749093
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
  • (6)
Cat. No. ABIN1724859
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (2)
Cat. No. ABIN523856
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN2781893
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN5579013
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN564554
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN523857
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Hamster, Horse, Human, Mouse, Rabbit
Application WB, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN2621472
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN961423
Quantity 50 μg
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6738123
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7269117
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (2)
Cat. No. ABIN2781894
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat
Application WB
Validations
  • (2)
Cat. No. ABIN2781895
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ICC, IF, FACS
Validations
  • (2)
Cat. No. ABIN5566465
Quantity 150 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN3032103
Quantity 0.4 mL
Datasheet Datasheet

Latest Publications for our Osteoactivin 抗体

Neal, Boyle, Budge, Safadi, Richardson: "The glycoprotein GPNMB attenuates astrocyte inflammatory responses through the CD44 receptor." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 73, (2019) (PubMed).

Oyewumi, Manickavasagam, Novak, Wehrung, Paulic, Moussa, Sondag, Safadi: "Osteoactivin (GPNMB) ectodomain protein promotes growth and invasive behavior of human lung cancer cells." in: Oncotarget, Vol. 7, Issue 12, pp. 13932-44, (2017) (PubMed).

Arosarena, Dela Cadena, Denny, Bryant, Barr, Thorpe, Safadi: "Osteoactivin Promotes Migration of Oral Squamous Cell Carcinomas." in: Journal of cellular physiology, Vol. 231, Issue 8, pp. 1761-70, (2016) (PubMed).

Frara, Abdelmagid, Tytell, Amin, Popoff, Safadi, Barbe: "Growth and repair factors, osteoactivin, matrix metalloproteinase and heat shock protein 72, increase with resolution of inflammation in musculotendinous tissues in a rat model of repetitive grasping." in: BMC musculoskeletal disorders, Vol. 17, pp. 34, (2016) (PubMed).

Kramer, Wegdam, Donker-Koopman, Ottenhoff, Gaspar, Verhoek, Nelson, Gabriel, Kallemeijn, Boot, Laman, Vissers, Cox, Pavlova, Moran, Aerts, van Eijk: "Elevation of glycoprotein nonmetastatic melanoma protein B in type 1 Gaucher disease patients and mouse models." in: FEBS open bio, Vol. 6, Issue 9, pp. 902-13, (2016) (PubMed).

Ruan, Li, Nie, Zhou, Zou: "Differential expression of glycoprotein non-metastatic melanoma protein B (GPNMB) involved in trichostatin A-induced apoptosis in gastric cancer." in: International journal of clinical and experimental medicine, Vol. 7, Issue 12, pp. 4857-66, (2015) (PubMed).

Abdelmagid, Sondag, Moussa, Belcher, Yu, Stinnett, Novak, Mbimba, Khol, Hankenson, Malcuit, Safadi: "Mutation in Osteoactivin Promotes Receptor Activator of NF?B Ligand (RANKL)-mediated Osteoclast Differentiation and Survival but Inhibits Osteoclast Function." in: The Journal of biological chemistry, Vol. 290, Issue 33, pp. 20128-46, (2015) (PubMed).

Gutknecht, Geiger, Joas, Dörfel, Salih, Müller, Grünebach, Rittig: "The transcription factor MITF is a critical regulator of GPNMB expression in dendritic cells." in: Cell communication and signaling : CCS, Vol. 13, pp. 19, (2015) (PubMed).

Fiorentini, Bodei, Bedussi, Fragni, Bonini, Simeone, Zani, Berruti, Missale, Memo, Spano, Sigala: "GPNMB/OA protein increases the invasiveness of human metastatic prostate cancer cell lines DU145 and PC3 through MMP-2 and MMP-9 activity." in: Experimental cell research, Vol. 323, Issue 1, pp. 100-11, (2014) (PubMed).

Qin, Liu, Yuan, Zhang, Li, Zhang, Xu, Wang: "Glycoprotein non-metastatic melanoma protein B as a predictive prognostic factor in clear-cell renal cell carcinoma following radical nephrectomy." in: Molecular medicine reports, Vol. 9, Issue 3, pp. 851-6, (2014) (PubMed).

Aliases for Osteoactivin 抗体

glycoprotein nmb (Gpnmb) 抗体
glycoprotein nmb (GPNMB) 抗体
glycoprotein (transmembrane) nmb (Gpnmb) 抗体
glycoprotein nmb L homeolog (gpnmb.L) 抗体
DC-HIL 抗体
Dchil 抗体
HGFIN 抗体
ipd 抗体
NMB 抗体
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