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Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis.
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Cow (Bovine) Polyclonal OAZ2 Primary Antibody for WB - ABIN2786667
Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007
Gene expression studies have identified altered expression of ornithine decarboxylase antizyme 2 in suicide completers with a history of mood disorders.
This study demomistrated that H3K4me3 modification plays an important role in up regulation of OAZ2 in prefrontal cortex.
elevated ODC (显示 ODC1 抗体) and low OAZ2 mRNA expression levels correlate with several unfavorable genetic and clinical features in neuroblastoma (显示 ARHGEF16 抗体).
The level of AZ2 mRNA decreased during mammary gland development.
Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase but does not accelerate its degradation.
ornithine decarboxylase antizyme 2
, ODC-Az 2
, antizyme 2
, seizure-related protein 15
, ODC antizyme, long form