ORM1-Like 3 (S. Cerevisiae) (ORMDL3) ELISA试剂盒

Negative regulator of sphingolipid synthesis. 再加上,我们可以发ORMDL3 抗体 (24)ORMDL3 蛋白 (4)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
ORMDL3 94103 Q8N138
小鼠 ORMDL3 ORMDL3 66612 Q9CPZ6
大鼠 ORMDL3 ORMDL3 360618 Q6QI25
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产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 15至18个工作日

适于 ORMDL3 相互作用对的更多 ELISA 试剂盒

Human ORM1-Like 3 (S. Cerevisiae) (ORMDL3) interaction partners

  1. These associations with ORMDL3 are cell type specific, with the most significant 17q21 genotype effects on ORMDL3 expression and HSPA5 (显示 HSPA5 ELISA试剂盒) induction evident in B cells. Together, these findings have implications for how the interaction of increased ORMDL3 and rhinovirus may predispose to asthma.

  2. Chromosome 17q21 genes ORMDL3 and GSDMB (显示 GSDMB ELISA试剂盒) are linked to asthma and other immune diseases. (Review)

  3. The results confirmed that polymorphisms in NOD2 (显示 NOD2 ELISA试剂盒) (Leu1007insC) and IRGM (显示 IRGM ELISA试剂盒) genes are associated with increased risk of Crohn's disease; whereas the ORMDL3 variant is associated with susceptibility to ulcerative colitis in the Lithuanian early-onset inflammatory bowel disease population.

  4. IRF-3 (显示 IRF3 ELISA试剂盒) is an important regulator of ORMDL3 induction following RSV infection by binding directly to the promoter of ORMDL3

  5. MiR (显示 MLXIP ELISA试剂盒)-665 induced apoptosis by inhibiting XBP1 (显示 XBP1 ELISA试剂盒) and ORMDL3.

  6. These studies suggest that increased levels of ORMDL3 contribute to antiviral defense to rhinovirus infection in mice (hORMDL3(zp3 (显示 ZP3 ELISA试剂盒)-Cre) mice which have universal increased expression of human ORMDL3) through pathways that may include IFNs (IFN-alpha (显示 IFNA ELISA试剂盒), IFN-beta (显示 IFNB1 ELISA试剂盒), IFN-lambda), OAS (显示 SMOC1 ELISA试剂盒), and RNAse L (显示 RNASEL ELISA试剂盒).

  7. this study demonstrated the upregulation of (显示 ATF6 ELISA试剂盒) ORMDL3 (显示 BECN1 ELISA试剂盒)in patients with systemic lupus erythematosus

  8. ORMDL3 might influence de novo sphingolipid metabolism downstream of serine palmitoyltransferase

  9. modest changes (8-13%) in promoter methylation levels of ZPBP2 (显示 ZPBP2 ELISA试剂盒) and GSDMA may cause substantial changes in RNA levels and allelic expression of ZPBP2 (显示 ZPBP2 ELISA试剂盒) and ORMDL3 is mediated by DNA methylation (显示 HELLS ELISA试剂盒)

  10. Decreased ORMDL3 expression increased levels of free sphingoid bases and sphingoid base phosphates, and also caused increases in cellular levels of ceramides.

Mouse (Murine) ORM1-Like 3 (S. Cerevisiae) (ORMDL3) interaction partners

  1. Expression levels of ORMDL3, phosphorylated (p)ERK (显示 EPHB2 ELISA试剂盒) and MMP9 (显示 MMP9 ELISA试剂盒) were significantly greater in the asthmamodel group; however, in the group pretreated with budesonide their expression was reduced.

  2. ORMDL3 mediates the autophagy via the ATF 6 (显示 ATF6 ELISA试剂盒)-Beclin1 (显示 BECN1 ELISA试剂盒) autophagy pathway, and it facilitates the survival of splenic B cells via promoting autophagy and suppressing apoptosis

  3. ORMDL3 might influence de novo sphingolipid metabolism downstream of serine palmitoyltransferase

  4. inhibiting ORMDL3 in airway epithelial cells plays a significant role in induction of allergen-induced increases in airway hyperresponsiveness

  5. ORMDL3, an asthma susceptibility gene identified by genome-wide association studies, contributes to key pathways that promote changes in airway physiology during allergic immune responses.

  6. Mediated by GATA3 (显示 GATA3 ELISA试剂盒) through targeting promoter region of ORMDL3.

  7. Downregulation of ORMDL3 expression in mast cells enhances AKT (显示 AKT1 ELISA试剂盒) and NF-kappaB (显示 NFKB1 ELISA试剂盒)-directed signaling pathways and chemotaxis and contributes to the development of mast cell-mediated local inflammation in vivo.

  8. overexpression of ORMDL3 regulates ceramide homeostasis in cells in a complex manner and suggest that local FTY720 administration might be a useful therapeutic intervention for the control of allergic asthma.

  9. the contribution of ORMDL3 to asthma risk may involve changes in sphingolipid metabolism

  10. These studies provide evidence that ORMDL3 plays an important role in vivo in airway remodeling potentially through ATF6 (显示 ATF6 ELISA试剂盒) target genes.

ORMDL3 抗原简介

Antigen Summary

Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling (By similarity).

Gene names and symbols associated with ORMDL3

  • ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) 抗体
  • ORM1-like 3 (S. cerevisiae) (Ormdl3) 抗体
  • ORMDL sphingolipid biosynthesis regulator 3 (Ormdl3) 抗体
  • 2810011N17Rik 抗体
  • AI315223 抗体
  • LRRGT00183 抗体

Protein level used designations for ORMDL3

ORM1-like protein 3 , liver regeneration-related protein LRRGT00183

94103 Homo sapiens
66612 Mus musculus
360618 Rattus norvegicus
615368 Bos taurus
100479284 Ailuropoda melanoleuca
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