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NUAK1 抗体

(NUAK Family, SNF1-Like Kinase, 1 (NUAK1))
Serine/threonine-protein kinase involved in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progression. Phosphorylates ATM, CASP6, LATS1, PPP1R12A and p53/TP53. Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability. Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex. Acts by mediating PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1. May be involved in 392' and is recruited to the CDKN1A/WAF1 promoter to participate to transcription activation by p53/TP53. May also act as a tumor malignancy-associated factor by promoting tumor invasion and metastasis under regulation and phosphorylation by AKT1. Suppresses Fas-induced apoptosis by mediating phosphorylation of CASP6, thereby suppressing the activation of the caspase and the subsequent cleavage of CFLAR.
NUAK1 抗体  (AA 451-550) NUAK1 抗体  (AA 451-550) NUAK1 抗体 (AA 451-550) (ABIN716396)

NUAK1 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

NUAK1 抗体  (AA 1-661) NUAK1 抗体  (AA 1-661) NUAK1 抗体 (AA 1-661) (ABIN523287)

NUAK1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

NUAK1 抗体  (C-Term) NUAK1 抗体  (C-Term) NUAK1 抗体 (C-Term) (ABIN392640)

NUAK1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3521 unconjugated

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NUAK1 抗体 by 适用

Find NUAK1 抗体 for a variety of species such as anti-Human NUAK1, anti-Mouse NUAK1, anti-Hamster NUAK1. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular NUAK1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN716396
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN523287
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN392640
Quantity 200 μL
Datasheet Datasheet
Reactivity Hamster, Human, Mouse
Application WB, IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN392639
Quantity 400 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN5014025
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7238549
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN7259682
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN6263759
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, FACS
Validations
  • (1)
Cat. No. ABIN570930
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7268966
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN5014026
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN716398
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN883458
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN883459
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF (cc), IF (p)
Validations
Cat. No. ABIN2809925
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our NUAK1 抗体

Humbert, Navaratnam, Augert, Da Costa, Martien, Wang, Martinez, Abbadie, Carling, de Launoit, Gil, Bernard: "Regulation of ploidy and senescence by the AMPK-related kinase NUAK1." in: The EMBO journal, Vol. 29, Issue 2, pp. 376-86, (2010) (PubMed).

Niesler, Myburgh, Moore: "The changing AMPK expression profile in differentiating mouse skeletal muscle myoblast cells helps confer increasing resistance to apoptosis." in: Experimental physiology, Vol. 92, Issue 1, pp. 207-17, (2007) (PubMed).

Suzuki, Lu, Kusakai, Kishimoto, Ogura, Esumi: "ARK5 is a tumor invasion-associated factor downstream of Akt signaling." in: Molecular and cellular biology, Vol. 24, Issue 8, pp. 3526-35, (2004) (PubMed).

Kusakai, Suzuki, Ogura, Kaminishi, Esumi: "Strong association of ARK5 with tumor invasion and metastasis." in: Journal of experimental & clinical cancer research : CR, Vol. 23, Issue 2, pp. 263-8, (2004) (PubMed).

Suzuki, Kusakai, Kishimoto, Lu, Ogura, Esumi: "ARK5 suppresses the cell death induced by nutrient starvation and death receptors via inhibition of caspase 8 activation, but not by chemotherapeutic agents or UV irradiation." in: Oncogene, Vol. 22, Issue 40, pp. 6177-82, (2003) (PubMed).

Suzuki, Kusakai, Kishimoto, Lu, Ogura, Lavin, Esumi: "Identification of a novel protein kinase mediating Akt survival signaling to the ATM protein." in: The Journal of biological chemistry, Vol. 278, Issue 1, pp. 48-53, (2002) (PubMed).

Aliases for NUAK1 抗体

NUAK family kinase 1 (NUAK1) 抗体
NUAK family, SNF1-like kinase, 1 (Nuak1) 抗体
ARK5 抗体
AU014801 抗体
AW494241 抗体
B230104P22Rik 抗体
Omphk1 抗体
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