anti-NOP2/Sun Domain Family, Member 2 (NSUN2) 抗体

NSUN2 encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. 再加上,我们可以发NSUN2 蛋白 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
NSUN2 28114 Q1HFZ0
NSUN2 54888 Q08J23
NSUN2 361191  
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antibodies-online.cn销售最多的anti-NSUN2 抗体

Showing 10 out of 41 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-NSUN2 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Hela cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 WB NSUN2 Antibody (Center) (ABIN654767) western blot analysis in mouse spleen tissue lysates (35 µg/lane). This demonstrates the NSUN2 antibody detected the NSUN2 protein (arrow). 400 μL Log in to see 10至11个工作日
$324.50
详细
非结合性 ICC, IF, IHC, IHC (p), WB Western Blot: NSUN2 Antibody [NBP1-86878] - Lane 1: Marker [kDa] 207, 110, 79, 49, 32, 25, 17.Lane 2: Human cell line RT-4.Lane 3: Human cell line EFO-21.Lane 4: Human cell line A-431 Immunohistochemistry-Paraffin: NSUN2 Antibody [NBP1-86878] - Staining of human heart muscle shows strong nuclear membrane positivity in myocytes. 0.1 mL Log in to see 10至13个工作日
$491.63
详细
非结合性 EIA, WB <span>NSUN2 Antibody (Center) western blot analysis in mouse spleen tissue lysates (35µg/lane).This demonstrates the NSUN2 antibody detected the NSUN2 protein (arrow).</span> 0.4 mL Log in to see 6至8个工作日
$390.50
详细
Cow 非结合性 WB 50 μg Log in to see 7至9个工作日
$551.83
详细
非结合性 WB Western Blot at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: Jurkat whole cell lysate Lysates/proteins at 20 ug per lane. Western blot analysis in mouse spleen tissue lysates (35ug/lane). 400 μL Log in to see 2至3个工作日
$515.63
详细
非结合性 IF, IHC, WB 100 μL Log in to see 16 Days
$476.15
详细
Cow 非结合性 WB   100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 ELISA, WB 50 μg Log in to see 2至3个工作日
$446.88
详细
非结合性 WB Western Blot: NSUN2 Antibody [NBP1-53052] - Hela cell lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 8至11个工作日
$485.88
详细

通过反应活性、应用领域、克隆类型和共轭标记 NSUN2 抗体

特性 应用范围 宿主 克隆类型 标记
Mouse (Murine)


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Human ,


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Rat (Rattus)


引用最多的anti-NSUN2 抗体

  1. Human Polyclonal NSUN2 Primary Antibody for ICC, IF - ABIN4340777 : Horn, Kim, Wright, Wong, Stewart, Burke, Roux: A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton. in The Journal of cell biology 2013 (PubMed)
    Show all 6 Pubmed References

  2. Cow (Bovine) Polyclonal NSUN2 Primary Antibody for WB - ABIN2783512 : Sakita-Suto, Kanda, Suzuki, Sato, Takata, Tatsuka: Aurora-B regulates RNA methyltransferase NSUN2. in Molecular biology of the cell 2007 (PubMed)
    Show all 2 Pubmed References

更多抗NSUN2的相互作用对抗体

Mouse (Murine) NOP2/Sun Domain Family, Member 2 (NSUN2) interaction partners

  1. study identified NSun2 as a novel component of the chromatoid body and show that NSun2 is essential for germ cell differentiation in the testis

  2. Steady-state levels of unmethylated tRNAs were substantially reduced, and loss of Dnmt2 (显示 TRDMT1 抗体) and NSun2 was further associated with reduced rates of overall protein synthesis.

  3. NSUN2 localizes to the nucleolus of Purkinje cells in the cerebellum. Mutation to arginine at residue 679 causes NSUN2 to fail to localize within the nucleolus.

  4. we identify that an RNA methyltransferase (Misu/Nsun2) is required to balance stem cell self-renewal and differentiation in skin

  5. Misu is a novel downstream Myc (显示 MYC 抗体) target that methylates RNA polymerase III transcripts. Misu mediates Myc (显示 MYC 抗体)-induced cell proliferation and growth and is a potential target for cancer therapies.

  6. These results suggest a novel mechanism by which c-Myc promotes proliferation by stabilizing the mitotic spindle in fast-dividing cells via Misu and NuSAP.

Human NOP2/Sun Domain Family, Member 2 (NSUN2) interaction partners

  1. Dysregulation of ALYREF (显示 THOC4 抗体)-mediated mRNA export upon NSUN2 depletion could be restored by reconstitution of wild-type but not methyltransferase-defective NSUN2.

  2. methylation at m6A (显示 GPM6A 抗体) by METTL3 (显示 METTL3 抗体)/METTL14 (显示 METTL14 抗体) facilitates the methylation of m5C by NSUN2, and vice versa. NSUN2-mediated m5C and METTL3 (显示 METTL3 抗体)/METTL14 (显示 METTL14 抗体)-mediated m6A (显示 GPM6A 抗体) methylation synergistically enhance p21 (显示 CDKN1A 抗体) expression at the translational level

  3. Findings indicate the critical impact of RNA methyltransferase NSUN2-mediated mRNA methylation in promoting premature senescence.

  4. Our findings provide a unique insight into the roles and effects of NSUN2 overexpression in breast cancer cells

  5. findings point to YB-1 (显示 YBX1 抗体) and NSUN2 as possible mediators of the process of transfer of specific mRNAs into exosomes, allowing us to speculate on an involvement of these proteins in the mRNA sorting via the recognition of the above motifs

  6. These findings indicate that NSun2-mediated mRNA methylation regulates p27 (显示 PAK2 抗体) and CDK1 (显示 CDK1 抗体) levels during replicative senescence.

  7. A novel homozygous variant c.1020delA in NSUN2 gene segregated in an autosomal recessive mode in the family of a child with intellectual disability. It causes a frameshift and premature stop codon, decreasing mRNA levels.

  8. By methylating the CDK1 (显示 CDK1 抗体) mRNA at the 3'UTR (显示 UTS2R 抗体), NSun2 enhances the translation of CDK1 (显示 CDK1 抗体), thereby influencing entry into and the progression of the cell division cycle.

  9. tRNA modifying enzymes, NSUN2 and METTL1 (显示 METTL1 抗体), determine sensitivity to 5-fluorouracil in HeLa cells

  10. Report frequencies of short tandem repeat markers linked to TUSC3 (MRT7 (显示 TUSC3 抗体)) or NSUN2 (MRT5) genes used for homozygosity mapping of recessive intellectual disability.

NSUN2 抗原简介

蛋白简介

This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene names and symbols associated with NSUN2

  • NOL1/NOP2/Sun domain family member 2 (Nsun2) 抗体
  • NOP2/Sun RNA methyltransferase family member 2 (NSUN2) 抗体
  • NOP2/Sun RNA methyltransferase family, member 2 (Nsun2) 抗体
  • NOP2/Sun RNA methyltransferase family member 2 S homeolog (nsun2.S) 抗体
  • D13Wsu123e 抗体
  • MISU 抗体
  • MRT5 抗体
  • RGD1311954 抗体
  • SAKI 抗体
  • TRM4 抗体

Protein level used designations for NSUN2

Myc-induced SUN domain containing protein , NOL1/NOP2/Sun domain family 2 , myc-induced SUN domain-containing protein , tRNA (cytosine(34)-C(5))-methyltransferase , tRNA (cytosine-5-)-methyltransferase NSUN2 , NOL1/NOP2/Sun domain family, member 2 , NOP2/Sun domain family, member 2 , 5-methycytoisine methyltransferase , Myc-induced SUN-domain-containing protein , NOL1/NOP2/Sun domain family member 2 , hTrm4 , substrate of AIM1/Aurora kinase B , tRNA methyltransferase 4 homolog

GENE ID SPECIES
28114 Mus musculus
420938 Gallus gallus
54888 Homo sapiens
516044 Bos taurus
361191 Rattus norvegicus
414460 Xenopus laevis
anti-NSUN2 (NSUN2) 抗体 精选生产商
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