NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 2, 8kDa 蛋白 (NDUFA2)

The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. 再加上,我们可以发NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 2, 8kDa 抗体 (29)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
大鼠 NDUFA2 NDUFA2 291660  
NDUFA2 17991 Q9CQ75
NDUFA2 4695 O43678
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大肠杆菌(E. Coli) His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
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大肠杆菌(E. Coli) 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
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酵母菌 Pongo pygmaeus His tag   1 mg Log in to see 60至71个工作日
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NDUFA2 蛋白 by Origin and Source

Origin 在表达 标记
Mouse (Murine)

Human , ,
, ,

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Mouse (Murine) NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 2, 8kDa (NDUFA2) interaction partners

  1. The authors use green fluorescent-tagged complex I subunits to determine the kinetics of assembly. Tagged human NDUFA2 may incorporate into the holo-complex I enzyme as an assembly intermediate or as free monomers. The authors conclude that nuclear-encoded subunits incorporate into the holo-enzyme in a subunit-specific manner.

  2. The authors determine the NMR structure of the oxidized human NDUFA2 protein, also known as B8, and report that its structure and redox potential is similar to that of thioredoxins. The highly conserved residues on the surface most likely form the protein-protein interaction site of this subunit with the large multimeric complex I.

  3. differentially expressed in the brains of four mice strains; expression pattern follows ethanol preference of the strains [(NADH-ubiquinone oxidoreductase B8 subunit]

Human NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 2, 8kDa (NDUFA2) interaction partners

  1. A novel mechanism of lipoteichoic acid (LTA)-induced cytokine induction in human peripheral blood cells involves uptake of LTA and subsequent intracellular recognition driven by Toll-like receptor (TLR)2, TLR6, and CD14.

  2. solution structure shows a thioredoxin fold with highest similarities to the human thioredoxin mutant C73S and thioredoxin 2 from Anabeana sp

Cow (Bovine) NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 2, 8kDa (NDUFA2) interaction partners

  1. Both the rate of the NADH-OH binding and its affinity to complex I are strongly decreased in the presence of succinate. The effect of succinate is completely reversed by rotenone, antimycin A, and uncoupler.

蛋白简介NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 2, 8kDa (NDUFA2)

蛋白简介

The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with NDUFA2

  • NADH:ubiquinone oxidoreductase subunit A2 (Ndufa2)
  • NADH:ubiquinone oxidoreductase subunit A2 (NDUFA2)
  • NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (Ndufa2)
  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa (Ndufa2)
  • NADH:ubiquinone oxidoreductase subunit A2 (ndufa2)
  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2 (Ndufa2)
  • AV000592 蛋白
  • B8 蛋白
  • C1-B8 蛋白
  • CD14 蛋白
  • CI-B8 蛋白
  • CIB8 蛋白
  • NDUFA2 蛋白

Protein level used designations for NDUFA2

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 , NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa , NADH-ubiquinone oxidoreductase B8 subunit , OXPHOS complex I B8 subunit , complex I-B8 , NADH-ubiquinone oxidoreductase subunit CI-B8 , complex I B8 subunit , NADH-ubiquinone oxidoreductase complex , CI-B8

GENE ID SPECIES
291660 Rattus norvegicus
462119 Pan troglodytes
478032 Canis lupus familiaris
693085 Bombyx mori
768860 Gallus gallus
100117608 Nasonia vitripennis
100124807 Xenopus (Silurana) tropicalis
17991 Mus musculus
4695 Homo sapiens
327698 Bos taurus
100173647 Pongo abelii
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