Myelin Protein Zero-Like 2 (MPZL2) ELISA试剂盒

Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. 再加上,我们可以发MPZL2 抗体 (64)MPZL2 蛋白 (10)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
 MPZL2 MPZL2 10205 O60487
小鼠 MPZL2 MPZL2 14012  
大鼠 MPZL2 MPZL2 300679  
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适于 MPZL2 相互作用对的更多 ELISA 试剂盒

Human Myelin Protein Zero-Like 2 (MPZL2) interaction partners

  1. CLCA2 (显示 CLCA2 ELISA试剂盒) links junctional adhesion molecule (显示 AMICA1 ELISA试剂盒) EVA1, to cytosolic signaling proteins that modulate proliferation and differentiation.

  2. Findings highlight Eva1 as a novel regulator of GIC function and also provide new mechanistic insight into the role of noncanonical NF-kappaB (显示 NFKB1 ELISA试剂盒) activation in GIC.

  3. EVA (显示 SLC26A4 ELISA试剂盒) is expressed in human choroid plexus epithelial cells and CD4 (显示 CD4 ELISA试剂盒) T lymphocytes and regulates CD4 (显示 CD4 ELISA试剂盒)+ T lymphocyte adhesion to human choroid plexus epithelial cells in vitro. These data suggest a novel mechanism to regulate CNS immune surveillance.

Mouse (Murine) Myelin Protein Zero-Like 2 (MPZL2) interaction partners

  1. EVA deficiency results in increased experimental autoimmune encephalomyelitis disease severity. EVA-knockout Mice have normal immune system development and choroid plexus morphology.

  2. modulation of Eva1 expression in thymocytes is crucial for lymphocyte physiological developmental progression and stromal differentiation

  3. These results suggest that EVA expressed in choroid plexus cells may regulate the permeability of the blood-CSF (显示 CSF2 ELISA试剂盒) barrier.

MPZL2 抗原简介

Antigen Summary

Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain\; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with MPZL2

  • myelin protein zero-like 2b (mpzl2b) 抗体
  • myelin protein zero like 2 (MPZL2) 抗体
  • myelin protein zero-like 2 (Mpzl2) 抗体
  • cb837 抗体
  • Eva 抗体
  • Eva1 抗体
  • mpzl2 抗体
  • wu:fb07b02 抗体

Protein level used designations for MPZL2

epithelial V-like antigen 1 , myelin protein zero-like 2 , myelin protein zero-like protein 2

336830 Danio rerio
419779 Gallus gallus
699330 Macaca mulatta
10205 Homo sapiens
14012 Mus musculus
300679 Rattus norvegicus
540423 Bos taurus
489384 Canis lupus familiaris
100172793 Pongo abelii