Mannosyl (Alpha-1,3-)-Glycoprotein beta-1,4-N-Acetylglucosaminyltransferase, Isozyme A 蛋白 (MGAT4A)

MGAT4A encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. 再加上,我们可以发Mannosyl (Alpha-1,3-)-Glycoprotein beta-1,4-N-Acetylglucosaminyltransferase, Isozyme A 抗体 (17)Mannosyl (Alpha-1,3-)-Glycoprotein beta-1,4-N-Acetylglucosaminyltransferase, Isozyme A 试剂盒 (13)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
MGAT4A 11320 Q9UM21
MGAT4A 269181 Q812G0
MGAT4A 367252 Q5M854
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大肠杆菌(E. Coli) His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
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Insect Cells rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50至55个工作日
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Insect Cells 小鼠 rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50至55个工作日
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大肠杆菌(E. Coli) 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
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酵母菌 大鼠 His tag   1 mg Log in to see 60至71个工作日
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MGAT4A 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, ,
Mouse (Murine) ,
,
Rat (Rattus)

更多Mannosyl (Alpha-1,3-)-Glycoprotein beta-1,4-N-Acetylglucosaminyltransferase, Isozyme A (MGAT4A)互动伙伴

Human Mannosyl (Alpha-1,3-)-Glycoprotein beta-1,4-N-Acetylglucosaminyltransferase, Isozyme A (MGAT4A) interaction partners

  1. GnT-IVa may contribute to the malignancy of choriocarcinoma by promoting cell adhesion, migration and invasion through glycosylation of integrin beta1 and LAMP-2.

  2. Data suggest microRNA-424 regulates expression of MGAT4A (mannoside beta-1,4-N-acetylglucosaminyltransferase A), OGT (O-linked N-acetylglucosamine transferase), and GALNT13 (polypeptide N-acetylgalactosaminyltransferase 13) in mammary epithelium.

  3. Findings suggest that GnT-IVa is involved in regulating invasion of choriocarcinoma through modifications of the oligosaccharide chains of beta1 integrin.

  4. upregulation of mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetyl-glucosaminyl-transferase is associated with metastatic colorectal carcinoma

  5. analysis of expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer

  6. GnT-IVa is more active than GnT-IVb under physiological conditions and it primarily contributes to the biosynthesis of N-glycans.

  7. We investigated mRNA levels of glycosyltransferases, namely, N-acetylglucosaminyltransferase a (GnT)-IVa, and found that (GnT)-IVa expression was decreased in HLE-cells Epirubicin resistant.

  8. The results of this work suggest that in T2D subjects, high levels of glucose and triglycerides are accompanied by an increase on MGAT4A mRNA levels and WBC count; condition that suggests a pro-inflammatory state due to a chronic metabolic stress.

  9. GNT-IV genetic variation is not associated with gastric cancer.

Mouse (Murine) Mannosyl (Alpha-1,3-)-Glycoprotein beta-1,4-N-Acetylglucosaminyltransferase, Isozyme A (MGAT4A) interaction partners

  1. our results suggest that let-7c may inhibit the metastatic ability of Hca-F cells, at least partially, via repressing Mgat4a activity.

  2. Mutagenesis of this gene encoding GnT-4a glycosyltransferase is studied and its association with Diabetes type 2.

蛋白简介Mannosyl (Alpha-1,3-)-Glycoprotein beta-1,4-N-Acetylglucosaminyltransferase, Isozyme A (MGAT4A)

蛋白简介

This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme B, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1, 4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation.

Gene names and symbols associated with MGAT4A

  • mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A (MGAT4A)
  • mannoside acetylglucosaminyltransferase 4, isoenzyme A (Mgat4a)
  • mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A (Mgat4a)
  • 9530018I07Rik 蛋白
  • glcNAc-T-IVa 蛋白
  • GnT-4a 蛋白
  • GNT-IV 蛋白
  • GnT-IVa 蛋白

Protein level used designations for MGAT4A

N-acetylglucosaminyltransferase IVa , N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa , UDP-GlcNAc:a-1,3-D-mannoside b-1,4-acetylglucosaminyltransferase IV , UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa , UDP-N-acetylglucosamine:alpha1,3-d-mannoside beta1,4-N-acetylglucosaminyltransferase , alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A , alpha-1,3-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase , glcNAc-T IVa , mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isoenzyme A , gnT-IVa , mannoside acetylglucosaminyltransferase 4, isoenzyme A , UDP-N-acetylglucosamine: alpha1,3-d-mannoside beta1,4-N-acetylglucosaminyltransferase

GENE ID SPECIES
11320 Homo sapiens
269181 Mus musculus
367252 Rattus norvegicus
418692 Gallus gallus
282276 Bos taurus
100338722 Oryctolagus cuniculus
101108820 Ovis aries
100524079 Sus scrofa
474562 Canis lupus familiaris
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