Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1) ELISA试剂盒

MAN1B1 encodes an enzyme belonging to the glycosyl hydrolase 47 family. 再加上,我们可以发MAN1B1 抗体 (22)MAN1B1 蛋白 (9)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
 MAN1B1 MAN1B1 11253 Q9UKM7
小鼠 MAN1B1 MAN1B1 227619 A2AJ15
大鼠 MAN1B1 MAN1B1 499751 B2GUY0
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适于 MAN1B1 相互作用对的更多 ELISA 试剂盒

Human Mannosidase, Alpha, Class 1B, Member 1 (MAN1B1) interaction partners

  1. Data show that HIV-1 env protein interacts with alpha-mannosidases ERManI (MAN1B1) and initiates endoplasmic reticulum (ER)-associated protein degradation (ERAD) pathway degradation process.

  2. The properties of ERMAN1 enable rapid selection of endoplasmic reticulum-associated degradation substrates in the endoplasmic reticulum.ERMAN1 digests mono-, di- and tri (显示 VANGL2 ELISA试剂盒)-glucosylated N-glycans.

  3. we linked mutations in MAN1B1 to a Golgi glycosylation disorder. Additionally, our results support the recent findings on MAN1B1 localization

  4. MAN1B1 deficiency appeared to be a frequent cause in our cohort of patients with unsolved congenital disorder of glycosylation type II.

  5. A novel post-transcriptional regulatory mechanism for ERManI via miR (显示 MLXIP ELISA试剂盒)-125b and this molecule contributes to the regulation of carcinogenesis in hepatocellular carcinoma.

  6. ERManI and gamma-COP (显示 COPg1 ELISA试剂盒) contribute to a golgi-based quality control module that facilitates the retrieval of captured ERAD substrates back to the endoplasmic reticulum.

  7. A homozygous nonsense mutation in MAN1B1 segregated with nonsyndromic autosomal-recessive intellectual disability and additional dysmorphic features.

  8. ER processing alpha1,2-mannosidase (显示 MAN1A2 ELISA试剂盒) (ER ManI (显示 FAM168B ELISA试剂盒)) has a role in ER-associated degradation of misfolded proteins

  9. Modification by endoplasmic reticulum mannosidase I (ERManI) contributes to the preferential selection of the misfolded AAT monomer for proteasomal degradation.

  10. overexpression of Golgi alpha1,2-mannosidase IA, IB, and IC also accelerates ERAD of terminally misfolded human alpha1-antitrypsin variant null (Hong Kong) (NHK), and mannose trimming from the N-glycans on NHK in 293 cells

MAN1B1 抗原简介

Antigen Summary

This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11.

Gene names and symbols associated with MAN1B1

  • mannosidase alpha class 1B member 1 (MAN1B1) 抗体
  • mannosidase, alpha, class 1B, member 1 L homeolog (man1b1.L) 抗体
  • endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (LOC480667) 抗体
  • mannosidase, alpha, class 1B, member 1 (man1b1) 抗体
  • mannosidase, alpha, class 1B, member 1 (Man1b1) 抗体
  • E430019H13Rik 抗体
  • ERMan1 抗体
  • Gm108 抗体
  • MAN1B1 抗体
  • MANA-ER 抗体
  • MRT15 抗体
  • RGD1563595 抗体

Protein level used designations for MAN1B1

mannosidase, alpha, class 1B, member 1 , alpha 1,2-mannosidase , ER alpha 1,2-mannosidase , Man9GlcNAc2-specific processing alpha-mannosidase , endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase , endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 1 , ER alpha-1,2-mannosidase , ER mannosidase 1 , man9GlcNAc2-specific-processing alpha-mannosidase

417296 Gallus gallus
447291 Xenopus laevis
473099 Pan troglodytes
480667 Canis lupus familiaris
100145194 Xenopus (Silurana) tropicalis
11253 Homo sapiens
227619 Mus musculus
499751 Rattus norvegicus