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The product of MLX belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. 再加上，我们可以发MAX-Like Protein X 抗体 (95) 和 MAX-Like Protein X 蛋白 (6)和数多这个蛋白质的别的产品。
MLX promotes myogenesis not via an adjustment of glucose metabolism but rather by inducing the expression of several myokines, including insulin-like growth factor 2 (IGF2 (显示 IGF2 ELISA试剂盒))
Glucose is required at two additional steps to stimulate the transcription activation function of MondoA (显示 MLXIP ELISA试剂盒)-Mlx complexes.
Overexpression of dominant negative Mlx improves glucose intolerance by inhibiting expression not only of lipogenic enzymes but also other important genes such as Glucose-6-phosphatase (显示 G6PC ELISA试剂盒) and Elovl6 (显示 ELOVL6 ELISA试剂盒).
MYC (显示 MYC ELISA试剂盒) is part of a network of bHLHLZ proteins centered on the MYC (显示 MYC ELISA试剂盒) heterodimeric partner MAX and its counterpart, the MAX-like protein MLX.
Knockdown of MondoA (显示 MLXIP ELISA试剂盒), or its dimerization partner Mlx, blocks Myc (显示 MYC ELISA试剂盒)-induced reprogramming of multiple metabolic pathways, resulting in apoptosis
Data show that for both MondoA (显示 MLXIP ELISA试剂盒) and Mlx, the C-terminal domain CRM-1 (显示 XPO1 ELISA试剂盒) has cytoplasmic localization activity that is required by the protein monomers to accumulate in the cytoplasm.
Mlx is an obligatory partner of ChREBP (显示 MLXIPL ELISA试剂盒) in regulating lipogenic enzyme genes in liver.
Endogenous MondoA (显示 MLXIP ELISA试剂盒) and Mlx associate with mitochondria in primary skeletal muscle.
The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
MAX-like protein X
, transcription factor-like protein 4
, max-like protein X
, BigMax alpha
, MAX-like bHLHZIP protein
, protein BigMax
, transcription factor like 4
, transcription factor-like 4
, transcription factor max-like protein X
, BigMax protein
, class D basic helix-loop-helix protein 13
, max-like factor protein