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Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. 再加上，我们可以发KDM3B 蛋白 (3) 和 和数多这个蛋白质的别的产品。
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findings indicate that Kdm3b is required for normal spermatogenesis and sexual behaviors in male mice
These results demonstrate that Kdm3b-mediated H3K9 demethylation plays essential roles in maintenance of the circulating IGF-1 (显示 IGF1 抗体), postnatal somatic growth, circulating 17beta-estradiol, and female reproductive function.
we found that KDM3B exhibits potential tumor-suppressive activity and transcriptionally modulates HOXA1 (显示 HOXA1 抗体) expression via RARE in AML (显示 RUNX1 抗体).
H3K9 demethylase (显示 MBD2 抗体) KDM3B represses transcription of the angiogenesis regulatory gene, ANGPT1 (显示 ANGPT1 抗体).
High expression of KDM3B and KDM5A (显示 KDM5A 抗体) is associated with a better prognosis (no recurrence after mastectomy p=0.005 and response to docetaxel p=0.005)in breast cancer patients.
evidence that the H3K9-me1 (显示 ME1 抗体)/2 demethylase (显示 MBD2 抗体) KDM3B might play a role in leukemogenesis via activation of lmo2 (显示 LMO2 抗体) through interdependent actions with the histone acetyltransferase (显示 HAT 抗体) complex containing CBP (显示 CREBBP 抗体)
A novel nuclear protein (显示 RDBP 抗体), 5qNCA is a candidate for the myeloid leukemia (显示 BCL11A 抗体) tumor suppressor gene on chromosome 5 band q31.
Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
lysine (K)-specific demethylase 3B
, jumonji domain containing 1B
, lysine-specific demethylase 3B-like
, jmjC domain-containing histone demethylation protein 2B
, jumonji domain-containing protein 1B
, lysine-specific demethylase 3B
, nuclear protein 5qNCA