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Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. 再加上，我们可以发KDM3B 蛋白 (3) 和 和数多这个蛋白质的别的产品。
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Human Polyclonal KDM3B Primary Antibody for ELISA, WB - ABIN543158
Lai, Godley, Joslin, Fernald, Liu, Espinosa, Zhao, Pamintuan, Till, Larson, Qian, Le Beau: Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q). in Genomics 2001
Show all 3 Pubmed References
findings indicate that Kdm3b is required for normal spermatogenesis and sexual behaviors in male mice
These results demonstrate that Kdm3b-mediated H3K9 demethylation plays essential roles in maintenance of the circulating IGF-1, postnatal somatic growth, circulating 17beta-estradiol, and female reproductive function.
we found that KDM3B exhibits potential tumor-suppressive activity and transcriptionally modulates HOXA1 expression via RARE in AML.
H3K9 demethylase KDM3B represses transcription of the angiogenesis regulatory gene, ANGPT1.
High expression of KDM3B and KDM5A is associated with a better prognosis (no recurrence after mastectomy p=0.005 and response to docetaxel p=0.005)in breast cancer patients.
evidence that the H3K9-me1/2 demethylase KDM3B might play a role in leukemogenesis via activation of lmo2 through interdependent actions with the histone acetyltransferase complex containing CBP
A novel nuclear protein, 5qNCA is a candidate for the myeloid leukemia tumor suppressor gene on chromosome 5 band q31.
Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
lysine (K)-specific demethylase 3B
, jumonji domain containing 1B
, lysine-specific demethylase 3B-like
, jmjC domain-containing histone demethylation protein 2B
, jumonji domain-containing protein 1B
, lysine-specific demethylase 3B
, nuclear protein 5qNCA