anti-Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1) 抗体

Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation (By similarity).. 再加上,我们可以发Lrig1 蛋白 (11)Lrig1 试剂盒 (1)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
Lrig1 26018 Q96JA1
Lrig1 16206 P70193
Lrig1 312574  
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antibodies-online.cn销售最多的anti-Lrig1 抗体

Showing 10 out of 68 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
小鼠 山羊 非结合性 CyTOF, FACS, ICC, WB Detection of LRIG1 in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 mouse endothelioma cell line was stained with Goat Anti-Mouse LRIG1 Antigen Affinity-purified Polyclonal Antibody. Detection of Mouse LRIG1 by Western Blot. Western blot shows lysates of bEnd.3 mouse endothelioma cell line untreated (-), treated (+) or mock treated (m) with 30 pmol mouse LRIG1 or mouse ERK1 siRNA. PVDF membrane was probed with 2 ug/mL of Goat Anti-Mouse LRIG1 Antigen Affinity-purified Polyclonal Antibody  This experiment was conducted under reducing conditions. 100 μg Log in to see 8至9个工作日
$416.30
详细
绵羊 非结合性 CyTOF, FACS, IHC Detection of LRIG1 in LNCaP Human Cell Line by Flow Cytometry. LNCaP human prostate cancer cell line was stained with Sheep Anti-Human LRIG1 Antigen Affinity-purified Polyclonal Antibody. LRIG1 in Human Kidney. LRIG1 was detected in immersion fixed paraffin-embedded sections of human kidney using Sheep Anti-Human LRIG1 Antigen Affinity-purified Polyclonal Antibody. Tissue was stained using the Anti-Sheep HRP-DAB Cell & 100 μg Log in to see 8至9个工作日
$416.30
详细
小鼠 PE FACS Detection of LRIG1 in LNCaP Human Cell Line by Flow Cytometry. LNCaP human prostate cancer cell line was stained with Mouse Anti-Human LRIG1 PE-conjugated Monoclonal Antibody. 25 Tests Log in to see 8至9个工作日
$223.10
详细
小鼠 APC FACS Detection of LRIG1 in LNCaP Human Cell Line by Flow Cytometry. LNCaP human prostate cancer cell line was stained with Mouse Anti-Human LRIG1 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8至9个工作日
$387.55
详细
小鼠 非结合性 CyTOF, FACS, ICC, IHC Detection of LRIG1 in LNCaP Human Cell Line by Flow Cytometry. LNCaP human prostate cancer cell line was stained with Mouse Anti-Human LRIG1 Monoclonal Antibody. LRIG1 in Human Kidney. LRIG1 was detected in immersion fixed paraffin-embedded sections of human kidney using Mouse Anti-Human LRIG1 Monoclonal Antibody. Tissue was stained using the Anti-Mouse HRP-DAB Cell & 100 μg Log in to see 8至9个工作日
$299.00
详细
小鼠 山羊 PE FACS Detection of LRIG1 in D3 Mouse Cell Line by Flow Cytometry. D3 mouse embryonic stem cell line was stained with Goat Anti-Mouse LRIG1 PE-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Log in to see 8至9个工作日
$334.65
详细
绵羊 Alexa Fluor 488 FACS Detection of LRIG1 in LNCaP Hman Cell Line by Flow Cytometry. LNCaP human prostate cancer cell line was stained with Sheep Anti-Human LRIG1 Alexa Fluor 488-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Log in to see 8至9个工作日
$363.40
详细
非结合性 IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-LRIG1 Polyclonal Antibody, Unconjugated (ABIN735263) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Lane 1: mouse brain lysates Lane 2: mouse embryo lysates probed with Anti LRIG1 Polyclonal Antibody, Unconjugated (ABIN735263) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 120kD. Observed band size: 120kD. 100 μL Log in to see 3至7个工作日
$306.90
详细
小鼠 非结合性 WB Western blot analysis in mouse stomach tissue lysates (35ug/lane). 400 μL Log in to see 2至3个工作日
$515.63
详细
非结合性 WB Western blot analysis of extract of various cells, using LRIG1 antibody. 100 μL Log in to see 16 Days
$334.77
详细

引用最多的anti-Lrig1 抗体

  1. Mouse (Murine) Polyclonal Lrig1 Primary Antibody for CyTOF, FACS - ABIN4900308 : Jensen, Driskell, Watt: Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis. in Nature protocols 2010 (PubMed)
    Show all 14 Pubmed References

  2. Mouse (Murine) Polyclonal Lrig1 Primary Antibody for WB - ABIN1881506 : Ye, Gao, Xu, Zeng, Ou, Mao, Wang, He, Wang, Yang, Guo, Lei: Upregulation of LRIG1 suppresses malignant glioma cell growth by attenuating EGFR activity. in Journal of neuro-oncology 2009 (PubMed)
    Show all 2 Pubmed References

  3. Mouse (Murine) Polyclonal Lrig1 Primary Antibody for FACS - ABIN4897517 : Wong, Stange, Page, Buczacki, Wabik, Itami, van de Wetering, Poulsom, Wright, Trotter, Watt, Winton, Clevers, Jensen: Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling. in Nature cell biology 2012 (PubMed)

  4. Human Polyclonal Lrig1 Primary Antibody for CyTOF, FACS - ABIN4900286 : Oh, Lee, Choi, Suh, Shim, Song, Kim, Lee, Oh, Jeong, Cheong, Song, Kim: USP8 modulates ubiquitination of LRIG1 for Met degradation. in Scientific reports 2014 (PubMed)

更多抗Lrig1的相互作用对抗体

Human Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1) interaction partners

  1. MiR (显示 MLXIP 抗体)-183 overexpression promoted radioresistance of glioblastoma via down-regulating LRIG1 and increasing the activity of EFGR (显示 EGFR 抗体)/Akt (显示 AKT1 抗体).

  2. LRIG1 is a negative regulator of RET2A and RET2B and is also downregulated in papillary and medullary thyroid carcinoma

  3. LRIG1 expression in human GC tissues is inversely correlated with miR (显示 MLXIP 抗体)-20a and EGFR (显示 EGFR 抗体).

  4. Role of LRIG1 in cancer [review]

  5. LRIG1 expression may represent a barrier to EMT (显示 ITK 抗体)

  6. LRIG1 role in the atrophic epidermis

  7. Downregulation of LRIG1 expression in oral verrucous carcinoma tissue is reported.

  8. LRIG1, as a negative mediated gene of tumor, can inhibit biological function of PAs (显示 PASK 抗体) via inhibiting PI3K (显示 PIK3CA 抗体)/AKT (显示 AKT1 抗体) and Ras/Raf (显示 RAF1 抗体)/ERK (显示 EPHB2 抗体) pathways, and it might be a new target for gene therapy ofPituitary adenomas

  9. LRIG1 and Fascin-1 (显示 FSCN1 抗体) were differently expressed in cancer and normal lung tissue in patients with NSCLC, which could be a biomarker for mediastinal lymph node metastasis in NSCLC patients.

  10. Results suggest that the LRIG1could negatively control MRP-1 (显示 MDM4 抗体) and the apoptosis to improve the sensitivity of VP16-related chemotherapy.

Mouse (Murine) Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1) interaction partners

  1. Lrig1 marks gastric corpus epithelial progenitor cells capable of repopulating the damaged oxyntic mucosa by differentiating into normal gastric lineage cells in mouse stomach.

  2. findings reveal a novel and essential role of Lrig1 in regulating morphogenic events that shape the hippocampal circuits and establish that the assembly of TrkB (显示 NTRK2 抗体) with Lrig1 represents a key mechanism for understanding how specific neuronal populations expand the repertoire of responses to BDNF (显示 BDNF 抗体) during brain development

  3. LRIG1 role in the atrophic epidermis

  4. LRIG1+ cells were found to re-populate the neo-epidermis on day 14, suggesting an important homeostatic role of LRIG1 in skin

  5. a subset of human duodenal tumors exhibited features of LRIG1(-/-) adenomas, including loss of LRIG1, gastric metaplasia (MUCIN5AC and MUCIN6), and increased amphiregulin (显示 AREG 抗体) and Egfr (显示 EGFR 抗体) activity.

  6. LRIG1 regulates the postnatal development of ICC-DMP and ICC-SMP from smooth muscle progenitors in mice.

  7. Loss of one Apc (显示 APC 抗体) allele in Lrig1(+) cells results in inducible stem cell-driven model that recapitulates features of familial adenomatous polyposis.

  8. At later stages, Lrig1 expression is sustained in non-sensory tissues, whereas Lrig2 levels are enhanced in neurons and sensory epithelia.

  9. LRIG1 orchestrates corneal-tissue transparency and cell fate during repair via STAT3 (显示 STAT3 抗体).

  10. A review summarizes the data that LRIG1 is a ERBB (显示 EGFR 抗体) negative regulator and tumour suppressor.

Lrig1 抗原简介

蛋白简介

Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation (By similarity).

Gene names and symbols associated with Lrig1

  • leucine rich repeats and immunoglobulin like domains 1 (LRIG1) 抗体
  • leucine-rich repeats and immunoglobulin-like domains 1 (Lrig1) 抗体
  • D6Bwg0781e 抗体
  • Img 抗体
  • LIG-1 抗体
  • LIG1 抗体

Protein level used designations for Lrig1

leucine-rich repeat protein LRIG1 , leucine-rich repeats and immunoglobulin-like domains protein 1 , ortholog of mouse integral membrane glycoprotein LIG-1 , integral membrane glycoprotein

GENE ID SPECIES
26018 Homo sapiens
16206 Mus musculus
312574 Rattus norvegicus
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