Leucine Rich Repeat (In FLII) Interacting Protein 2 蛋白 (LRRFIP2)

May function as an activator of the canonical Wnt signaling pathway upstream of ctnnb1/beta-catenin. 再加上,我们可以发LRRFIP2 抗体 (52)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
LRRFIP2 9209 Q9Y608
LRRFIP2 71268 Q91WK0
LRRFIP2 301035 Q4V7E8
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产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
大肠杆菌(E. Coli) 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
$4,744.22
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
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HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10至12个工作日
$860.20
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
$414.29
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酵母菌 Cow His tag   1 mg Log in to see 60至71个工作日
$3,107.50
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酵母菌 Xenopus tropicalis His tag   1 mg Log in to see 60至71个工作日
$3,120.33
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酵母菌 大鼠 His tag   1 mg Log in to see 60至71个工作日
$3,223.00
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LRRFIP2 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

更多Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2)互动伙伴

Human Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2) interaction partners

  1. FATylation of LRRFIP2 occurs on two distinct sites, each being modified by a single FAT10 (显示 UBD 蛋白) moiety.

  2. A novel exonic rearrangement affecting MLH1 (显示 MLH1 蛋白) and the contiguous LRRFIP2 is a founder mutation in Portuguese Lynch syndrome families

  3. Unambiguous characterization of site-specific phosphorylation of leucine-rich repeat Fli-I-interacting protein 2 (LRRFIP2) in Toll-like receptor 4 (TLR4 (显示 TLR4 蛋白))-mediated signaling.

  4. These data suggest that LRRFIP2 plays an important role in transducing Wnt (显示 WNT2 蛋白) signals.

  5. LRR-binding MyD88 (显示 MYD88 蛋白) interactor LRRFIP2 is a positive regulator of NF-kappa B (显示 NFKB1 蛋白) activity and is also a positive regulator of cytokine production in lipopolysaccharide-stimulated macrophages, suggesting a functional role in TLR4 (显示 TLR4 蛋白)-mediated inflammatory response.

Mouse (Murine) Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2) interaction partners

  1. LRRFIP2 inhibits NLRP3 (显示 NLRP3 蛋白) inflammasome activation by recruiting the caspase-1 (显示 CASP1 蛋白) inhibitor Flightless-I, thus outlining a new mechanism for negative regulation of NLRP3 (显示 NLRP3 蛋白) inflammasome.

  2. Unambiguous characterization of site-specific phosphorylation of leucine-rich repeat Fli-I-interacting protein 2 (LRRFIP2) in Toll-like receptor 4 (TLR4 (显示 TLR4 蛋白))-mediated signaling.

蛋白简介LRRFIP2

蛋白简介

May function as an activator of the canonical Wnt signaling pathway upstream of ctnnb1/beta-catenin. May be required for dorsal axis formation (By similarity).

Gene names and symbols associated with LRRFIP2

  • leucine rich repeat (in FLII) interacting protein 2 (lrrfip2)
  • LRR binding FLII interacting protein 2 (LRRFIP2)
  • LRR binding FLII interacting protein 1 (LRRFIP1)
  • LRR binding FLII interacting protein 2 (lrrfip2)
  • leucine rich repeat (in FLII) interacting protein 2 (Lrrfip2)
  • LRR binding FLII interacting protein 2 (Lrrfip2)
  • leucine rich repeat (in FLII) interacting protein 2 L homeolog (lrrfip2.L)
  • 5133400F20Rik 蛋白
  • AI850587 蛋白
  • HUFI-2 蛋白
  • LRRFIP2 蛋白
  • wu:fj34c02 蛋白
  • zgc:63771 蛋白
  • zgc:113956 蛋白

Protein level used designations for LRRFIP2

leucine-rich repeat flightless-interacting protein 2 , leucine rich repeat (in FLII) interacting protein 2 , similar to leucine rich repeat (in FLII) interacting protein 1 , LRR FLII-interacting protein 2 , leucine-rich repeat flightless-interacting protein 2-like , xLRRFIP2

GENE ID SPECIES
335838 Danio rerio
420759 Gallus gallus
470788 Pan troglodytes
485582 Canis lupus familiaris
698661 Macaca mulatta
704379 Macaca mulatta
100073400 Ornithorhynchus anatinus
100158569 Xenopus (Silurana) tropicalis
100338416 Oryctolagus cuniculus
100406422 Callithrix jacchus
100435736 Pongo abelii
100481318 Ailuropoda melanoleuca
100555804 Anolis carolinensis
100592598 Nomascus leucogenys
100626059 Sus scrofa
9209 Homo sapiens
100050285 Equus caballus
71268 Mus musculus
301035 Rattus norvegicus
510368 Bos taurus
444248 Xenopus laevis
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