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Plays a role in the regulation of cell morphology and cytoskeletal organization.. 再加上,我们可以发 和 和数多这个蛋白质的别的产品。
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The expression of circLARP4 was downregulated in GC tissues and represented an independent prognostic factor for overall survival of GC patients.
The results indicate that LARP4 is a posttranscriptional regulator of ribosomal protein production in mammalian cells and suggest that this activity can be controlled by tRNA levels.
A cytoplasmic isoform of La protein as well as LARPs 6, 4, and 1 function in mRNA metabolism and translation in distinct but similar ways, sometimes with the poly(A)-binding protein, and in some cases by direct binding to poly(A)-RNA.
LARP4 inhibits migration and invasion of cancer cells, and that some cancer-associated mutations stimulate these effects of LARP4.
Involvement of LARP4 as a target of TNF-alpha-TTP regulation provides a clue as to how its functional activity may be used in a physiologic pathway.
The results demonstrate that the La modules of the human LARP4 is also active in tRNA-mediated suppression, even in the absence of stable UUU-3'OH trailer protection.
LARP4 activity is integrated with other PAM2 protein activities by PABP as part of mRNA homeostasis.
The c-MPL protein altered expression provide an opportunity to diagnose and identify subpopulations of MPD patients.
FISH study showed no cytogenetic abnormalities in any of the analyzed cases.
Mouse LARP4 is regulated by TNF-alpha in a TTP-dependent manner.
Plays a role in the regulation of cell morphology and cytoskeletal organization.
La ribonucleoprotein domain family, member 4 , c-Mpl binding protein , la-related protein 4