anti-LIM Domain Binding 3 (LDB3) 抗体

LDB3 encodes a PDZ domain-containing protein. 再加上,我们可以发LIM Domain Binding 3 Protein 蛋白 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
LDB3 11155 O75112
LDB3 24131 Q9JKS4
LDB3 498587  
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antibodies-online.cn销售最多的anti-LIM Domain Binding 3 Protein 抗体

Showing 10 out of 72 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
山羊 非结合性 ELISA, WB ABIN185471 (0.01 ug/ml) staining of human muscle lysate (35 ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. 100 μg Log in to see 6至7个工作日
$358.02
详细
小鼠 非结合性 ELISA, WB LDB3 monoclonal antibody (M06A), clone 3C8 Western Blot analysis of LDB3 expression in A-431. Detection limit for recombinant GST tagged LDB3 is approximately 0.03 ng/mL as a capture antibody. 200 μL Log in to see 8至11个工作日
$461.00
详细
山羊 非结合性 IHC (p), IHC, ELISA, WB ABIN250866 (0.01?g/ml) staining of Human Muscle lysate (35?g protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Western Blot: LDB3 Antibody [ABIN250866] - (0.1ug/ml) staining of Human Skeletal Muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7至9个工作日
$485.88
详细
小鼠 非结合性 WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (56.87 KDa) . Dilution: 1:500~1000 100 μg Log in to see 8至11个工作日
$461.00
详细
Cow 非结合性 WB WB Suggested Anti-LDB3 Antibody Titration:  0.625ug/ml  Positive Control:  Human heart 100 μL Log in to see 2至3个工作日
$229.00
详细
非结合性 IHC, IHC (p), WB Western Blot: LDB3 Antibody [NBP2-19343] - Sample (30 ug of whole cell lysate) A: NT2D1 12% SDS PAGE gel, diluted at 1:1000. Immunohistochemistry-Paraffin: LDB3 Antibody [NBP2-19343] - Immunohistochemical analysis of paraffin-embedded Lung ADCA, using antibody at 1:500 dilution. 0.1 mL Log in to see 8至11个工作日
$514.63
详细
山羊 非结合性 ELISA, IHC, IHC (p), WB Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-LDB3 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml. 50 μg Log in to see 11至14个工作日
$484.00
详细
非结合性 IHC, IHC (p), WB Western Blot: LDB3 Antibody [NBP2-14190] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp Immunohistochemistry-Paraffin: LDB3 Antibody [NBP2-14190] - Staining of human heart muscle shows strong cytoplasmic positivity in myocytes. 0.1 mL Log in to see 10至13个工作日
$491.63
详细
Bat 非结合性 WB 100 μg Log in to see 7至9个工作日
$493.17
详细
小鼠 非结合性 IF, RNAi, ELISA, WB LDB3 monoclonal antibody (M06), clone 3C8 Western Blot analysis of LDB3 expression in A-431 . Western blot analysis of LDB3 over-expressed 293 cell line, cotransfected with LDB3 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with LDB3 monoclonal antibody (M06), clone 3C8. GAPDH ( 36.1 kDa ) used as specificity and loading control. 100 μg Log in to see 11至12个工作日
$440.00
详细

引用最多的anti-LIM Domain Binding 3 Protein 抗体

  1. Human Polyclonal LIM Domain Binding 3 Protein Primary Antibody for IHC (p), IHC - ABIN250866 : Huang, Zhou, Liang, Hollander, Sheikh, Li, Greaser, Shelton, Evans, Chen: Characterization and in vivo functional analysis of splice variants of cypher. in The Journal of biological chemistry 2003 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal LIM Domain Binding 3 Protein Primary Antibody for IF, RNAi - ABIN524582 : Arimura, Inagaki, Hayashi, Shichi, Sato, Hinohara, Vatta, Towbin, Chikamori, Yamashina, Kimura: Impaired binding of ZASP/Cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy. in Cardiovascular research 2009 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal LIM Domain Binding 3 Protein Primary Antibody for WB - ABIN4229314 : Methawasin, Hutchinson, Lee, Smith, Saripalli, Hidalgo, Ottenheijm, Granzier: Experimentally increasing titin compliance in a novel mouse model attenuates the Frank-Starling mechanism but has a beneficial effect on diastole. in Circulation 2014 (PubMed)

更多抗LIM Domain Binding 3 Protein的相互作用对抗体

Human LIM Domain Binding 3 (LDB3) interaction partners

  1. Interaction is demonstrated between ZASP and two new binding partners both of which have roles in signalling, regulation of gene expression and muscle differentiation; the mechanosensing protein Ankrd2 (显示 ANKRD2 抗体) and the tumour suppressor protein p53 (显示 TP53 抗体).

  2. p.(D117N) variant in Cypher/ZASP is not a causative mutation for dilated cardiomyopathy and ventricular arrhythmias.

  3. A novel heterozygous missense mutation (p.N155H) in a highly conserved PDZ (显示 INADL 抗体)-like motif of ZASP was identified. The results indicate that typical ZASP-MFM presenting with late-onset distal myopathy is commonly associated with mutations in PDZ (显示 INADL 抗体)-like motif of ZASP.

  4. The molecular basis for high-affinity binding of ZASP to G-Actin (显示 ACTB 抗体) has been described.

  5. this is the first family with Arrhythmogenic right ventricular cardiomyopathy where a mutation in LDB3 is associated with Arrhythmogenic right ventricular cardiomyopathy

  6. Study identified abnormal inclusion of LDB3 exon 11 specific to myotonic dystrophy type at the RNA and protein level; inclusion changed the affinity of LDB3 for PKC, indicating that exon 11 may contribute to the activation of PKC in DM1

  7. results show that MFM-associated ZASP mutations in the actin-binding domain have deleterious effects on the core structure of the Z-discs in skeletal muscle.

  8. Z-band alternatively spliced PDZ motif protein (ZASP) is the major O-linked beta-N-acetylglucosamine-substituted protein in human heart myofibrils

  9. This results of this indicted that One patient harbored the missense mutation c.1719G>A (p.V566M) in the ZASP gene.

  10. ZASP1 can form protein complex with telethonin/T-Cap (显示 TCAP 抗体) and Na(v)1.5. The left ventricular noncompaction-specific ZASP1 mutation can cause loss of function of Na(v)1.5, without significant alteration of the cytoskeletal protein (显示 ACTN1 抗体) complex.

Mouse (Murine) LIM Domain Binding 3 (LDB3) interaction partners

  1. Cypher and ENH (显示 PDLIM5 抗体) redundantly play an essential role in sustaining Z-line structure from the earliest stages of cardiac function, and are redundantly required to maintain normal embryonic heart function and embryonic viability.

  2. results show that MFM-associated ZASP mutations in the actin-binding domain have deleterious effects on the core structure of the Z-discs in skeletal muscle.

  3. Results indicte that Cypher/ZASP interacted with the regulatory subunit RIIalpha of PKA.

  4. Data demonstrated that the Z-disk proteins, ZASP, titin (显示 TTN 抗体) and vinculin (显示 VCL 抗体) preferentially bind to alpha-actinin-2 (显示 ACTN2 抗体).

  5. Deletion of long but not short Cypher isoforms leads to late-onset dilated cardiomyopathy.

  6. mutations of a structural/cytoskeletal protein (显示 ADD3 抗体), such as ZASP, lead to cardiac functional and electric abnormalities.

  7. Cypher isoforms are developmentally regulated in both skeletal and cardiac muscle

  8. Cypher plays a pivotal role in adult cardiac structure and function through protein-protein interactions with other Z-line proteins.

LIM Domain Binding 3 Protein (LDB3) 抗原简介

蛋白简介

This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified\; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains.

Gene names and symbols associated with anti-LIM Domain Binding 3 (LDB3) 抗体

  • LIM domain binding 3b (ldb3b) 抗体
  • LIM domain binding 3 S homeolog (ldb3.S) 抗体
  • LIM domain binding 3 (ldb3) 抗体
  • LIM domain binding 3 (LDB3) 抗体
  • LIM domain binding 3 (Ldb3) 抗体
  • AW742271 抗体
  • CMD1C 抗体
  • CYPHER 抗体
  • LDB3 抗体
  • ldb3l 抗体
  • LDB3Z1 抗体
  • LDB3Z4 抗体
  • LVNC3 抗体
  • MFM4 抗体
  • MGC52706 抗体
  • MGC75668 抗体
  • ORACLE 抗体
  • PDLIM6 抗体
  • RGD1564875 抗体
  • wu:fi31d08 抗体
  • ZASP 抗体
  • zgc:55814 抗体

Protein level used designations for anti-LIM Domain Binding 3 (LDB3) 抗体

LIM domain binding 3 , LIM domain binding 3 like , LIM domain-binding protein 3 , PDZ and LIM domain 6 , Z-band alternatively spliced PDZ-motif protein , protein cypher , PDZ-LIM domain protein , cypher , oracle protein , protein oracle

GENE ID SPECIES
334100 Danio rerio
379929 Xenopus laevis
394699 Xenopus (Silurana) tropicalis
697140 Macaca mulatta
100348927 Oryctolagus cuniculus
100582910 Nomascus leucogenys
11155 Homo sapiens
536781 Bos taurus
24131 Mus musculus
498587 Rattus norvegicus
479269 Canis lupus familiaris
100151883 Sus scrofa
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