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LMO7 encodes a protein containing a calponin homology (CH) domain, a PDZ domain, and a LIM domain, and may be involved in protein-protein interactions. 再加上，我们可以发LMO7 试剂盒 (6) 和 和数多这个蛋白质的别的产品。
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Human Polyclonal LMO7 Primary Antibody for ICC, IF - ABIN4331253
Wozniak, Baker, Chen, Wilson: The emerin-binding transcription factor Lmo7 is regulated by association with p130Cas at focal adhesions. in PeerJ 2013
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Human Polyclonal LMO7 Primary Antibody for ELISA, WB - ABIN561687
Hu, Guo, Li, Aronow, Zhang: LMO7 mediates cell-specific activation of the Rho-myocardin-related transcription factor-serum response factor pathway and plays an important role in breast cancer cell migration. in Molecular and cellular biology 2011
Human Polyclonal LMO7 Primary Antibody for ELISA, WB - ABIN250115
Putilina, Jaworski, Gentleman, McDonald, Kadiri, Wong: Analysis of a human cDNA containing a tissue-specific alternatively spliced LIM domain. in Biochemical and biophysical research communications 1998
lmo7(-/-) mice had no abnormalities in skeletal muscle morphology, physiological function, or regeneration. Lmo7 is dispensable for skeletal muscle and cardiac physiology and pathophysiology.
This study demonstrated that loss of Lmo7 in mice causes myopathic phenotypes similar to those seen in other EDMD mouse models.
Expressed in both B-cell lines and primary B-lymphocytes.
Increased susceptibility to spontaneous lung cancer in mice lacking LIM-domain only 7 is reported.
reveal the temporal and spatial expression patterns of this important gene during mouse, chicken and fish development and our findings suggest essential functions for LMO7 during vertebrate heart development
Data suggest that LMO7 interacts with MAD1 during spindle assembly phase of mitosis; LMO7 plays role in control of mitosis progression and exerts effect on spindle assembly checkpoint; LMO7 colocalizes with actin filaments; LMO7 does not colocalize with MAD1 at kinetochores in prometaphase nor at spindle poles in metaphase. (LMO7 = LIM domain only protein-7; MAD1 = mitotic spindle assembly checkpoint protein MAD1)
The miR-96-LMO7 axis may be a therapeutic target for lung cancer patients, and new diagnostic or therapeutic strategies could be developed by targeting the miR-96-LMO7 axis.
study suggested that the LMO7 gene may play an important role in the pathogenesis of DCM in the Han Chinese population.
Data suggest that Lmo7 is localized at the perinuclear region and in fibril-like structures along subsarcolemma of human skeletal myoblasts whereas in human myotubes Lmo7 is found diffuse throughout the cytoplasm.
show that LMO7 is upregulated in the stroma of invasive breast carcinoma in a manner that correlates with the increased expression of serum response factor target genes
functional interaction between emerin and Lmo7 is crucial for temporally regulating the expression of key myogenic differentiation genes.
Lmo7 positively regulates many EDMD-relevant genes (including emerin), and is feedback-regulated by binding to emerin.
This gene encodes a protein containing a calponin homology (CH) domain, a PDZ domain, and a LIM domain, and may be involved in protein-protein interactions. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, however, the full-length nature of some variants is not known.
LIM domain only 7
, LIM domain only protein 7
, TGF-beta induced protein
, LIM domain 7
, F-box only protein 20
, F-box protein Fbx20
, LIM domain only 7 protein
, zinc-finger domain-containing protein