anti-Killer Cell Lectin-Like Receptor, Subfamily A, Member 4 (Klra4) 抗体

Receptor on natural killer (NK) cells for class I MHC.. 再加上,我们可以发和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
Klra4 16635 Q60651
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Showing 5 out of 6 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
小鼠 大鼠 FITC FACS 50 μg Log in to see 10至12个工作日
小鼠 大鼠 PE FACS 100 μg Log in to see 10至12个工作日
小鼠 大鼠 Alexa Fluor 647 FACS 100 μg Log in to see 10至12个工作日
小鼠 大鼠 非结合性 FACS 500 μg Log in to see 10至12个工作日
小鼠 大鼠 非结合性 BR, FACS, IP   0.5 mg Log in to see 6至8个工作日

通过反应活性、应用领域、克隆类型和共轭标记 Klra4 抗体

特性 应用范围 宿主 克隆类型 标记
Mouse (Murine) ,

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引用最多的anti-Klra4 抗体

  1. Mouse (Murine) Monoclonal Klra4 Primary Antibody for BR, FACS - ABIN2689815 : Hanke, Takizawa, McMahon, Busch, Pamer, Miller, Altman, Liu, Cado, Lemonnier, Bjorkman, Raulet: Direct assessment of MHC class I binding by seven Ly49 inhibitory NK cell receptors. in Immunity 1999 (PubMed)


Mouse (Murine) Killer Cell Lectin-Like Receptor, Subfamily A, Member 4 (Klra4) interaction partners

  1. this study shows that after mouse cytomegalovirus infection, Ly49D augmented IFN-gamma (显示 IFNG 抗体) production by virus-specific Ly49H (显示 KLRA8 抗体)(+) NK cells and preferentially promoted the generation of memory Ly49H (显示 KLRA8 抗体)(+) NK cells

  2. The repertoire of inhibitory Ly49 receptors may be formed under the influenced of Fyn-dependent NK cell activation as well as the respective MHC class I environment.

  3. The Ly49D activation receptor on mouse NK cells specifically recognizes the Chinese hamster histocompatibility class I molecule associated with Chinese hamster beta 2-microglobulin (显示 B2M 抗体) (beta 2m) and is not tolerized in murine beta 2m deficiency.

  4. Activating Ly49D NK cell receptors are provided a mechanism for release from inhibitory receptor blockade that enables them to become important initiators of microbial, antiviral, and antitumor immunity.

  5. Coexpression of a Ly49A transgene partially rescued NKT (显示 CTSL1 抗体) cell development in Ly49D/H2-Dd transgenics.

  6. Glycosylation of Ly-49D at amino acid residues NTT221-23 reduces receptor binding to H-2Dd (显示 DHDH 抗体) tetramers and may represent a mechanism by which natural killer cells regulate affinity for host class I ligands.

  7. The MHC class I receptor Ly49D expressed on immature B cells recognizes MHC class I on peripheral tissues, inducing secretion of low levels of IFN-gamma (显示 IFNG 抗体) and thereby down-regulating immature B cell homing to the lymph nodes or to sites of inflammation.

  8. Ly49D stimulation triggers cellular activation of CD4 (显示 CD4 抗体) and CD8 (显示 CD8A 抗体) populations; Ly49D recognizes the classical hamster class I molecule Hm1-C4 on CHO (显示 COL11A1 抗体) cells, as demonstrated by the killing of Hm1-C4-transfected thymoma cells by Ly49D cytotoxic T cells.

  9. these data demonstrate that DAP10 (显示 HCST 抗体) does associate with Ly49H (显示 KLRA8 抗体) and Ly49D in primary NK cells.

Klra4 抗原简介


Receptor on natural killer (NK) cells for class I MHC.

Gene names and symbols associated with Klra4

  • killer cell lectin-like receptor, subfamily A, member 4 (Klra4) 抗体
  • Chok 抗体
  • Klra32 抗体
  • Ly-49d 抗体
  • Ly49d 抗体
  • ly49r<129> 抗体

Protein level used designations for Klra4

T-cell surface glycoprotein Ly-49D , killer cell lectin-like receptor 4 , killer cell lectin-like receptor subfamily A member 32 , lymphocyte antigen 49d

16635 Mus musculus
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