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Histone demethylase required for brain development. 再加上，我们可以发和数多这个蛋白质的别的产品。
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increased JHDM1D expression suppresses tumor growth by down-regulating angiogenesis under nutrient starvation
The KIAA1718, a PHF2/PHF8 (显示 PHF2 抗体) subfamily member, possesses histone demethylase (显示 MBD2 抗体) activity specific for H3K9 and H3K27, transcriptionally repressive histone marks.
KDM7A mediates TNF-alpha (显示 TNF 抗体)-induced ICAM1 (显示 ICAM1 抗体) protein upregulation.
G9a (显示 EHMT2 抗体) promotes H3K27 methylation of the E-cadherin (显示 CDH1 抗体) promoter by upregulating PCL3 (显示 PHF19 抗体) to increase PRC2 promoter recruitment and by downregulating the H3K27 demethylase (显示 MBD2 抗体) KDM7A to silence E-cadherin (显示 CDH1 抗体) gene
Histone modifier genes (JMJD1C (显示 JMJD1C 抗体), RREB1 (显示 RREB1 抗体), MINA (显示 MINA 抗体), KDM7A) alter conotruncal heart phenotypes in 22q11.2 deletion syndrome.
KIAA1718 is a dual-specificity histone demethylase (显示 MBD2 抗体) that regulates neural differentiation through FGF4 (显示 FGF4 抗体).
Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate (By similarity).
jmjC domain-containing histone demethylation protein 1D
, lysine-specific demethylase 7
, histone lysine demethylase JHDM1D
, jumonji C domain-containing histone demethylase 1 homolog D
, JmjC domain-containing histone demethylation protein 1D-B
, lysine-specific demethylase 7B
, jumonji C domain containing histone demethylase 1 homolog D
, lysine-specific demethylase 7A
, jumonji C domain containing histone demethylase 1
, lysine (K)-specific demethylase 7A
, lysine (K)-specific demethylase 7A L homeolog