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The protein encoded by IL1RL1 is a member of the interleukin 1 receptor family. 再加上，我们可以发IL1RL1 抗体 (127) 和 IL1RL1 试剂盒 (31)和数多这个蛋白质的别的产品。
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an increased prevalence in neonatal mortality was observed in litters from dams lacking ST2
Taken together, the data demonstrate a critical role of MyD88 (显示 MYD88 蛋白) in DCs and of IL-33 (显示 IL33 蛋白) signaling via ST2 (显示 SULT2A1 蛋白) in MC903-induced Atopic dermatitis (AD). These data suggest that IL-33 (显示 IL33 蛋白)/IL-33R may be a therapeutic target of AD.
Heligmosomoides polygyrus Alarmin Release Inhibitor (HpARI) prevents binding of active interleukin-33 (IL-33 (显示 IL33 蛋白)) to the IL-33 (显示 IL33 蛋白) receptor.
this study shows that ST2 (显示 SULT2A1 蛋白) regulates early IL-13 (显示 IL13 蛋白) production in fungus-induced allergic airway inflammation
mice deficient in the receptor for IL-33 (显示 IL33 蛋白) (Il1rl1-/-) demonstrated enhanced lung clearance of Aspergillus fumigatus
This stuidy shown that the mRNA expression of IL-33 and ST2 receptors is increased in the CNS of Rocio virus-infected WT mice and that ST2(-/-) mice showed increased susceptibility to infection.
Liver Treg cells show a high expression of ST2 (显示 SULT2A1 蛋白), a cellular receptor for tissue alarmin IL-33 (显示 IL33 蛋白), which is strongly upregulated in the liver of infected mice. These results illustrate the importance of IL-33 (显示 IL33 蛋白) in the suppressive function of liver Treg cells during Cytomegaloviruses (CMVs) infection.
these studies establish a basal defect in eosinophilopoiesis in IL-33 (显示 IL33 蛋白)- and ST2 (显示 SULT2A1 蛋白)-deficient mice and a mechanism whereby IL-33 (显示 IL33 蛋白) supports eosinophils by driving both systemic IL-5 (显示 IL5 蛋白) production and the expansion of IL-5Ralpha-expressing precursor cells
These results shed light on endogenous IL-33/ST2 signaling as a potential immune regulatory mechanism that serves to promote beneficial microglial responses and mitigate ischemic brain injury after stroke.
Plasmodium berghei infection triggered a dramatic increase of IL-33 expression by oligodendrocytes, through ST2 pathway.
present study highlights significant associations between ST2 and inflammatory bowel disease.
Data show that interleukin-2 receptor alpha (显示 IL2RA 蛋白), tumor necrosis factor receptor 1 (显示 TNFRSF1A 蛋白), serum STimulation-2 (IL1RL1 gene product), and regenerating islet-derived 3-alpha (显示 REG3A 蛋白) were significantly associated with non-relapse mortality.
Serum IL-33 (显示 IL33 蛋白) and sST2 (显示 SSTR2 蛋白) levels, and CD4 (显示 CD4 蛋白)+ST2L+ expression in peripheral blood mononuclear cells are closely associated with HIV-1 infection and immune reconstitution in patients received highly-active antiretroviral therapy.
Elevated levels of sST2 (显示 SSTR2 蛋白) concentration in stable coronary heart disease patients may independently predict short- and long-term risk for fatal CVD events and total mortality but not non-fatal CVD events.
Patients with severe aortic valve stenosis present elevated sST2 (显示 SSTR2 蛋白) levels. Left ventricular global longitudinal strain resulted the only independent predictor of sST2 (显示 SSTR2 蛋白) levels.
The Il1RL1 rs950880 AA homozygote is an independent predictor of all-cause mortality in coronary artery disease and peripheral arterial disease patients.
In a cohort of hypertensive heart failure subjects, soluble ST2 correlates significantly with indicators of right ventricular function.
Data provide evidence that increased IL-33/ST2 levels in patients with chronic kidney disease are an indicator of increased inflammation, impaired endothelial functions, and cardiovascular events.
Serum levels of IL33R were positively correlated with cognitive performance in patients with schizophrenia.
Interleukin 1 receptor-like 1 (ST2/IL1RL1) is a biomarker for cardiac stress and heart failure, which can be associated with cocaine use. Data suggest that serum ST2/IL1RL1 levels are up-regulated by cocaine use; cocaine use appears to be associated with subclinical cardiac stress and damage outside of acute cardiac events; elevated serum ST2/IL1RL1 levels may serve as biomarkers for cocaine-induced cardiac complications.
The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants.
, interleukin-1 receptor-like 1
, lymphocyte antigen 84
, protein T1
, growth stimulation-expressed
, homolog of mouse growth stimulation-expressed
, interleukin 1 receptor-related protein
, fos-responsive gene 1 protein