Interleukin 1 Receptor-Like 1 蛋白 (IL1RL1)

The protein encoded by IL1RL1 is a member of the interleukin 1 receptor family. 再加上,我们可以发IL1RL1 抗体 (127)IL1RL1 试剂盒 (31)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
IL1RL1 17082 P14719
IL1RL1 9173 Q01638
大鼠 IL1RL1 IL1RL1 25556 Q62611
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Showing 10 out of 23 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells 小鼠 rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50至55个工作日
大肠杆菌(E. Coli) His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
大肠杆菌(E. Coli) 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
HEK-293 Cells 非结合性   25 μg Log in to see 10至12个工作日
人细胞 Fc Tag 100 μg Log in to see 20至21个工作日
HEK-293 Cells Fc Tag Human IL-1RL1, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%. Immobilized Human IL-33, Tag Free  with a linear range of 1.95-7.8 ng/mL. 200 μg Log in to see 21至31个工作日
人细胞 小鼠 Fc Tag 100 μg Log in to see 20至21个工作日
人细胞 非结合性 100 μg Log in to see 20至21个工作日
CHO Cells DYKDDDDK Tag Validation with Western Blot 50 μg Log in to see 6至10个工作日

IL1RL1 蛋白 by Origin and Source

Origin 在表达 标记
Mouse (Murine) , , ,
, ,
Human , , , , ,
, , , ,

更多Interleukin 1 Receptor-Like 1 (IL1RL1)互动伙伴

Mouse (Murine) Interleukin 1 Receptor-Like 1 (IL1RL1) interaction partners

  1. an increased prevalence in neonatal mortality was observed in litters from dams lacking ST2

  2. Taken together, the data demonstrate a critical role of MyD88 (显示 MYD88 蛋白) in DCs and of IL-33 (显示 IL33 蛋白) signaling via ST2 (显示 SULT2A1 蛋白) in MC903-induced Atopic dermatitis (AD). These data suggest that IL-33 (显示 IL33 蛋白)/IL-33R may be a therapeutic target of AD.

  3. Heligmosomoides polygyrus Alarmin Release Inhibitor (HpARI) prevents binding of active interleukin-33 (IL-33 (显示 IL33 蛋白)) to the IL-33 (显示 IL33 蛋白) receptor.

  4. this study shows that ST2 (显示 SULT2A1 蛋白) regulates early IL-13 (显示 IL13 蛋白) production in fungus-induced allergic airway inflammation

  5. mice deficient in the receptor for IL-33 (显示 IL33 蛋白) (Il1rl1-/-) demonstrated enhanced lung clearance of Aspergillus fumigatus

  6. This stuidy shown that the mRNA expression of IL-33 and ST2 receptors is increased in the CNS of Rocio virus-infected WT mice and that ST2(-/-) mice showed increased susceptibility to infection.

  7. Liver Treg cells show a high expression of ST2 (显示 SULT2A1 蛋白), a cellular receptor for tissue alarmin IL-33 (显示 IL33 蛋白), which is strongly upregulated in the liver of infected mice. These results illustrate the importance of IL-33 (显示 IL33 蛋白) in the suppressive function of liver Treg cells during Cytomegaloviruses (CMVs) infection.

  8. these studies establish a basal defect in eosinophilopoiesis in IL-33 (显示 IL33 蛋白)- and ST2 (显示 SULT2A1 蛋白)-deficient mice and a mechanism whereby IL-33 (显示 IL33 蛋白) supports eosinophils by driving both systemic IL-5 (显示 IL5 蛋白) production and the expansion of IL-5Ralpha-expressing precursor cells

  9. These results shed light on endogenous IL-33/ST2 signaling as a potential immune regulatory mechanism that serves to promote beneficial microglial responses and mitigate ischemic brain injury after stroke.

  10. Plasmodium berghei infection triggered a dramatic increase of IL-33 expression by oligodendrocytes, through ST2 pathway.

Human Interleukin 1 Receptor-Like 1 (IL1RL1) interaction partners

  1. present study highlights significant associations between ST2 and inflammatory bowel disease.

  2. Data show that interleukin-2 receptor alpha (显示 IL2RA 蛋白), tumor necrosis factor receptor 1 (显示 TNFRSF1A 蛋白), serum STimulation-2 (IL1RL1 gene product), and regenerating islet-derived 3-alpha (显示 REG3A 蛋白) were significantly associated with non-relapse mortality.

  3. Serum IL-33 (显示 IL33 蛋白) and sST2 (显示 SSTR2 蛋白) levels, and CD4 (显示 CD4 蛋白)+ST2L+ expression in peripheral blood mononuclear cells are closely associated with HIV-1 infection and immune reconstitution in patients received highly-active antiretroviral therapy.

  4. Elevated levels of sST2 (显示 SSTR2 蛋白) concentration in stable coronary heart disease patients may independently predict short- and long-term risk for fatal CVD events and total mortality but not non-fatal CVD events.

  5. Patients with severe aortic valve stenosis present elevated sST2 (显示 SSTR2 蛋白) levels. Left ventricular global longitudinal strain resulted the only independent predictor of sST2 (显示 SSTR2 蛋白) levels.

  6. The Il1RL1 rs950880 AA homozygote is an independent predictor of all-cause mortality in coronary artery disease and peripheral arterial disease patients.

  7. In a cohort of hypertensive heart failure subjects, soluble ST2 correlates significantly with indicators of right ventricular function.

  8. Data provide evidence that increased IL-33/ST2 levels in patients with chronic kidney disease are an indicator of increased inflammation, impaired endothelial functions, and cardiovascular events.

  9. Serum levels of IL33R were positively correlated with cognitive performance in patients with schizophrenia.

  10. Interleukin 1 receptor-like 1 (ST2/IL1RL1) is a biomarker for cardiac stress and heart failure, which can be associated with cocaine use. Data suggest that serum ST2/IL1RL1 levels are up-regulated by cocaine use; cocaine use appears to be associated with subclinical cardiac stress and damage outside of acute cardiac events; elevated serum ST2/IL1RL1 levels may serve as biomarkers for cocaine-induced cardiac complications.



The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants.

Gene names and symbols associated with IL1RL1

  • interleukin 1 receptor-like 1 (Il1rl1)
  • interleukin 1 receptor like 1 (IL1RL1)
  • DER4 蛋白
  • FIT-1 蛋白
  • FIT1 蛋白
  • IL33R 蛋白
  • Ly84 蛋白
  • ST2 蛋白
  • St2-rs1 蛋白
  • ST2L 蛋白
  • ST2V 蛋白
  • T1 蛋白
  • T1/ST2 蛋白

Protein level used designations for IL1RL1

T1 , interleukin-1 receptor-like 1 , lymphocyte antigen 84 , protein T1 , growth stimulation-expressed , homolog of mouse growth stimulation-expressed , interleukin 1 receptor-related protein , fos-responsive gene 1 protein

17082 Mus musculus
9173 Homo sapiens
611442 Canis lupus familiaris
374136 Gallus gallus
25556 Rattus norvegicus
IL1RL1 蛋白 (IL1RL1) 精选生产商