Interferon, gamma-Inducible Protein 30 蛋白 (IFI30)

The protein encoded by IFI30 is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. 再加上,我们可以发IFI30 抗体 (51)IFI30 试剂盒 (16)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
IFI30 65972 Q9ESY9
IFI30 290644 Q499T2
IFI30 10437 P13284
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Showing 10 out of 11 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
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Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
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人细胞 His tag 100 μg Log in to see 20至21个工作日
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
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大肠杆菌(E. Coli) His tag 50 μg Log in to see 15至19个工作日
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HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 2至3个工作日
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酵母菌 野猪 His tag   1 mg Log in to see 60至71个工作日
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酵母菌 大鼠 His tag   1 mg Log in to see 60至71个工作日
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酵母菌 Cow His tag   1 mg Log in to see 60至71个工作日
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大肠杆菌(E. Coli) T7 tag,His tag 100 μg Log in to see 15至18个工作日
$704.00
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IFI30 蛋白 by Origin and Source

Origin 在表达 标记
Mouse (Murine)

Rat (Rattus)

Human , , , ,
, , ,

更多Interferon, gamma-Inducible Protein 30 (IFI30)互动伙伴

Zebrafish Interferon, gamma-Inducible Protein 30 (IFI30) interaction partners

  1. GILT expression is up-regulated in spleen and kidney after immunization with LPS (显示 IRF6 蛋白) although it also is constitutively expressed in heart, liver, muscle and intestine, suggesting that GILT may be involved in the immune response to bacterial challenge.

Mouse (Murine) Interferon, gamma-Inducible Protein 30 (IFI30) interaction partners

  1. GILT has a role in maintaining cysteine cathepsin proteolytic efficiency in phagosomes

  2. These results show that wild-type mouse fibroblasts are relatively resistant and GILT(-/-)mouse fibroblasts are susceptible to Dengue virus 2 entry and replication.

  3. Data indicate that in the absence of Gamma-interferon-inducible lysosomal thiol reductase (GIL (显示 AQP3 蛋白), CD4 (显示 CD4 蛋白)-positive T cell responses to major house dust mite allergen Der (显示 GDF3 蛋白) p 1 are significantly reduced.

  4. GILT has a critical role in regulating CD4 (显示 CD4 蛋白)(+) T-cell tolerance to an endogenous skin-restricted antigen relevant to controlling autoimmunity and generating effective immunotherapy for melanoma.

  5. We showed that STAT1 (显示 STAT1 蛋白) interacts with the GILT promoter, even in the absence of IFN-gamma (显示 IFNG 蛋白), and that STAT1 (显示 STAT1 蛋白) represses GILT expression.

  6. GILT has limited yet unexpected effect on self-peptide species presented by major histocompatibility complex class II antigens.

  7. study shows GILT facilitates MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8 (显示 CD8A 蛋白)+ T cells or cross-presentation;initiation of gB-specific CD8 (显示 CD8A 蛋白)+ T cell response during HSV-1 infection or cross-priming is GILT-dependent

  8. the thiol reductase activity of GILT is its essential function in MHC class II-restricted Ag processing

  9. GILT appears to have a fundamental role in cellular proliferation mediated through its influence on SOD2 (显示 SOD2 蛋白) protein activity and expression.

  10. findings show that endogenously produced peptide-IgG is processed by transduced splenic B cells in the lysosomes/endosomes in a GILT-dependent manner, and this endocytic processing pathway is essential for generating tolerogenic B cells

Human Interferon, gamma-Inducible Protein 30 (IFI30) interaction partners

  1. GILT functions as a host restriction factor against the retroviruses.

  2. GILT expression is anticipated to result in improved presentation of melanoma antigens and more effective antimelanoma T-cell responses.

  3. The lysosomal thiol reductase GILT expressed by antigen-presenting cells has diverse cellular and organismal functions. (Review)

  4. this review discusses recent studies that have advanced our understanding of the role of GILT in antigen processing and revealed surprising new functions for the enzyme.[review]

  5. Single nucleotide polymorphism of the interferon-gamma-inducible protein 30 gene is associated with hyperglycemia in severely obese individuals.

  6. GILT is required for efficient histocompatiblity class II-restricted processing of melanoma antigen tyrosinase-related protein 1 epitope in vitro and accelerates the onset of vitiligo in TRP1-specific T-cell receptor transgenic mice.

  7. Absence of gamma-interferon-inducible lysosomal thiol reductase in melanomas disrupts T cell recognition of select immunodominant epitopes.

  8. Role of the C-terminal propeptide in the activity and maturation of gamma -interferon-inducible lysosomal thiol reductase (GILT).

  9. GILT-expressing melanoma cells could prove to be very promising for direct antigen presentation and CD4 (显示 CD4 蛋白)+ T cell recognition

  10. studied gene expression profile of brain lesions of a patient with Neuromyelitis optica by using DNA microarray; found marked up-regulation of interferon gamma-inducible protein 30 (IFI30), CD163 (显示 CD163 蛋白), and secreted phosphoprotein 1 (SPP1 (显示 SPP1 蛋白), osteopontin (显示 SPP1 蛋白))

Pig (Porcine) Interferon, gamma-Inducible Protein 30 (IFI30) interaction partners

  1. The cloning and characterization of porcine gamma-interferon-inducible lysosomal thiol reductase (GILT) are reported.

蛋白简介IFI30

蛋白简介

The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing.

Gene names and symbols associated with IFI30

  • interferon, gamma-inducible protein 30 (ifi30)
  • IFI30, lysosomal thiol reductase (IFI30)
  • interferon gamma inducible protein 30 (LOC100304719)
  • interferon gamma inducible protein 30 (Ifi30)
  • IFI30, lysosomal thiol reductase (Ifi30)
  • GILT 蛋白
  • IFI-30 蛋白
  • IP30 蛋白
  • wu:fb12b04 蛋白
  • zgc:101752 蛋白

Protein level used designations for IFI30

LycGILT , gamma-interferon-inducible lysosomal thiol reductase , interferon, gamma-inducible protein 30 , interferon gamma inducible protein 30 , gamma-interferon-inducible protein IP-30 , lysosomal thio reductase IP30 , lysosomal thiol reductase IP30 , interferon gamma-inducible protein 30 preproprotein , legumaturain , gamma-inducible protein 30 , gamma-interferon-inducible-lysosomal thiol reductase

GENE ID SPECIES
336503 Danio rerio
420129 Gallus gallus
549950 Xenopus (Silurana) tropicalis
100304719 Ictalurus punctatus
65972 Mus musculus
290644 Rattus norvegicus
10437 Homo sapiens
615930 Bos taurus
100174943 Sus scrofa
IFI30 蛋白 (IFI30) 精选生产商
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