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ITPK1 抗体

(Inositol-Tetrakisphosphate 1-Kinase (ITPK1))
Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconverts the inositol tetrakisphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. Probably acts as the rate-limiting enzyme of the InsP6 pathway. Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain (By similarity). Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway.
ITPK1 抗体  (AA 1-314) ITPK1 抗体  (AA 1-314) ITPK1 抗体 (AA 1-314) (ABIN517270)

ITPK1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated

ITPK1 抗体  (AA 1-314) ITPK1 抗体  (AA 1-314) ITPK1 抗体 (AA 1-314) (ABIN561564)

ITPK1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2C8 unconjugated

ITPK1 抗体 ITPK1 抗体 ITPK1 抗体 (ABIN7267884)

ITPK1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

ITPK1 抗体 by 适用

Find ITPK1 抗体 for a variety of species such as anti-Human ITPK1, anti-Mouse ITPK1, anti-Rat ITPK1. The species listed below are among those available. Click on a link to go to the corresponding products.

ITPK1 抗体 by 应用范围

Find ITPK1 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

ITPK1 抗体 by 抗体来源

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ITPK1 抗体 by 抗原表位

Find ITPK1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

ITPK1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal ITPK1 抗体. Click on a link to go to the corresponding products.

ITPK1 抗体 by 克隆

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ITPK1 抗体 by 标记

Find ITPK1 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular ITPK1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (5)
Cat. No. ABIN517270
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (4)
Cat. No. ABIN561564
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN7267884
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC
Validations
  • (1)
  • (3)
Cat. No. ABIN2856549
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7156320
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (3)
Cat. No. ABIN517271
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN7264339
Quantity 200 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6741924
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6739033
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN2879401
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (p), IF (cc), ICC, IHC (p), IHC (fro)
Validations
Cat. No. ABIN6943845
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN6943846
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p), IF (cc)
Validations
Cat. No. ABIN6977513
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p), IF (cc)
Validations
Cat. No. ABIN6978374
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p), IF (cc)
Validations
Cat. No. ABIN6976652
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our ITPK1 抗体

Dovey, Diep, Clarke, Hale, McNamara, Guo, Brown, Cao, Grace, Gough, Bertin, Dixon, Fiedler, Mocarski, Kaiser, Moldoveanu, York, Carette: "MLKL Requires the Inositol Phosphate Code to Execute Necroptosis." in: Molecular cell, Vol. 70, Issue 5, pp. 936-948.e7, (2019) (PubMed).

Hollingsworth, Chen, Lee: "Integration of cell cycle control with transcriptional regulation by the retinoblastoma protein." in: Current opinion in cell biology, Vol. 5, Issue 2, pp. 194-200, (1993) (PubMed).

Lee, Shew, Hong, Sery, Donoso, Young, Bookstein, Lee: "The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity." in: Nature, Vol. 329, Issue 6140, pp. 642-5, (1987) (PubMed).

Aliases for ITPK1 抗体

inositol-tetrakisphosphate 1-kinase (ITPK1) 抗体
inositol 1,3,4-triphosphate 5/6 kinase (Itpk1) 抗体
inositol-tetrakisphosphate 1-kinase L homeolog (itpk1.L) 抗体
inositol-tetrakisphosphate 1-kinase a (itpk1a) 抗体
inositol-tetrakisphosphate 1-kinase (Itpk1) 抗体
BC031182 抗体
ITRPK1 抗体
wu:fj15d08 抗体
zgc:56075 抗体
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