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IP6K1 encodes a member of the inositol phosphokinase family. 再加上，我们可以发IP6K1 蛋白 (7)和数多这个蛋白质的别的产品。
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Human Polyclonal IP6K1 Primary Antibody for ICC, IF - ABIN4327446
Jadav, Chanduri, Sengupta, Bhandari: Inositol pyrophosphate synthesis by inositol hexakisphosphate kinase 1 is required for homologous recombination repair. in The Journal of biological chemistry 2013
IP6K1 physiologically regulates neuronal migration by binding to alpha-actinin (显示 ACTN1 抗体) and influencing phosphorylation of both FAK (显示 PTK2 抗体) and alpha-actinin (显示 ACTN1 抗体) through its product 5-diphosphoinositol pentakisphosphate.
provides the first evidence for the involvement of IP6Ks in dynein function and proposes that inositol pyrophosphate-mediated pyrophosphorylation may act as a regulatory signal to enhance dynein-driven transport
IP6K1 is also involved in early cytoskeleton remodeling events during cancer progression.
IP6K1 is a novel CRL4 subunit that transduces UV signals to mediate disassembly of the CRL4-CSN complex, thereby regulating nucleotide excision repair and cell death.
we identified IP6Ks as novel nuclear and cytosolic InsP6- (and InsP5-) dephosphorylating enzymes whose activity is sensitively driven by a decrease in the cellular ATP/ADP ratio
FGF2 (显示 FGF2 抗体)-signaling involves the inositol polyphosphate cascade, including inositol hexakisphosphate kinase (IP6K), and demonstrate that IP6K1,2 regulates Runx2 (显示 RUNX2 抗体) and osteoblast gene expression.
IHPK1 gene is disrupted at the 3p21.31 breakpoint of t(3;9) in a family with type 2 diabetes mellitus
Results report the characterization of an inhibitor, N(2)-(m-(trifluoromethy)lbenzyl) N(6)-(p-nitrobenzyl)purine (TNP), selective for inositol hexakisphosphate kinases.
juvenile spermatids from Ip6k1(-/-) mice display premature expression of the transition protein TNP2 (显示 TNP2 抗体) and the protamine PRM2 (显示 PRM2 抗体) due to translational derepression.
these findings reveal an important role for IP6K1 in regulating Mesenchymal stem/stromal cell fitness and differentiation fate.
IP6K1 is a novel regulator of PLIN1 (显示 PLIN1 抗体) mediated lipolysis
IP6K1 regulates energy metabolism via a mechanism that could potentially be targeted in obesity.
IP6K1 preferentially bound to the phospholipid phosphatidic acid, and this binding was required for IP6K1 nuclear localization and the regulation of inositol-3-phosphate synthase transcription.
present study demonstrates that IP6K1 physiologically regulates GSK3 kinases.
This gene encodes a member of the inositol phosphokinase family. The encoded protein may be responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternatively spliced transcript variants have been described.
inositol hexaphosphate kinase 1
, inositol hexakisphosphate kinase 1
, inositol hexakisphosphate kinase 6
, insP6 kinase 1
, ATP:1D-myo-inositol-hexakisphosphate phosphotransferase
, Pi uptake stimulator